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Generic Name : Buprenorphine
Pronunciation : byoo-pre-NOR-feen
Therapeutic Classification : opioid dependance agents
Trade Name(s):
India- Addnok, Bunogesic, Buprigesic, Buprinor, Pentorel, Tidigesic. International- Subutex. This medication is a narcotic analgesic, prescribed for moderate to severe pain. When it is not to be taken (Contraindications):
When it is to be taken : Adult- IM/SC/IV- The recommended dose is 0.3 to 0.6mg. Sublingual- The recommended dose is 0.2 to 0.4mg, tree or four times per day. How it should be taken : It comes as a solution for injection to be administered by a healthcare provider into the large muscle or into the vein. It also comes as a tablet to be placed under the tongue. Special Instruction : * Caution should be exercised in patients with history of slow breathing, drowsiness, stomach problems, diarrhea, head injury, stroke, mental illness, suicidal thoughts, lung or other breathing problem (chronic obstructive pulmonary disease [COPD]), underactive thyroid, changes in blood electrolytes level, enlarged prostate, urinary obstruction, seizures, liver or kidney disease, any allergy, who are taking other medications, elderly, children especially less than 2 years old, during pregnancy and breastfeeding. * It may cause drowsiness or dizziness, do not drive a car or operate machinery and get up slowly from bed while taking this medication. * Avoid alcohol consumption. Side Effects : Most Common - Nausea, vomiting, dizziness, increased sweating, headache, low blood pressure and shortness of breath. Central Nervous System - Confusion, blurred vision, emotion, weakness/fatigue, dry mouth, nervousness, depression, slurred speech and tingling. Heart - High blood pressure and fast or slow heart rate. Gastrointestinal - Constipation. Respiratory - Difficulty in breathing and bluish. Skin - Itching. Eye and ENT - Double vision and visual abnormalities. Miscellaneous - Injection site reaction, urinary retention, dreaming, flushing/warmth, and chills/cold, ringing in the ear, eye inflammation and mental illness. * Avoid excess dosage. Storage Conditions : Store it at room temperature (25°C) and away from excess heat and moisture. |
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