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Buprenorphine

Latest prescription information about Buprenorphine. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Buprenorphine
Pronunciation : byoo-pre-NOR-feen
Therapeutic Classification : opioid dependance agents
Trade Name(s): 
India- Addnok, Bunogesic, Buprigesic, Buprinor, Pentorel, Tidigesic.
International- Subutex.
Why it is prescribed (Indications) : 
This medication is a narcotic analgesic, prescribed for moderate to severe pain.

When it is not to be taken (Contraindications): 


Contraindicated during labor, and in people with known hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


When it is to be taken : 
Adult- IM/SC/IV- The recommended dose is 0.3 to 0.6mg.
Sublingual- The recommended dose is 0.2 to 0.4mg, tree or four times per day.
How it should be taken : 
It comes as a solution for injection to be administered by a healthcare provider into the large muscle or into the vein.
It also comes as a tablet to be placed under the tongue.
Special Instruction : 
* Caution should be exercised in patients with history of slow breathing, drowsiness, stomach problems, diarrhea, head injury, stroke, mental illness, suicidal thoughts, lung or other breathing problem (chronic obstructive pulmonary disease [COPD]), underactive thyroid, changes in blood electrolytes level, enlarged prostate, urinary obstruction, seizures, liver or kidney disease, any allergy, who are taking other medications, elderly, children especially less than 2 years old, during pregnancy and breastfeeding.
* It may cause drowsiness or dizziness, do not drive a car or operate machinery and get up slowly from bed while taking this medication.
* Avoid alcohol consumption.
Side Effects : 
Most Common - Nausea, vomiting, dizziness, increased sweating, headache, low blood pressure and shortness of breath.
Central Nervous System - Confusion, blurred vision, emotion, weakness/fatigue, dry mouth, nervousness, depression, slurred speech and tingling.
Heart - High blood pressure and fast or slow heart rate.
Gastrointestinal - Constipation.
Respiratory - Difficulty in breathing and bluish.
Skin - Itching.
Eye and ENT - Double vision and visual abnormalities.
Miscellaneous - Injection site reaction, urinary retention, dreaming, flushing/warmth, and chills/cold, ringing in the ear, eye inflammation and mental illness.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it at room temperature (25°C) and away from excess heat and moisture.

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