Generic Name : Bretylium Tosylate Injection Pronunciation : breh-TILL-ee-uhm TAH-sill-ate Therapeutic Classification : Antiarrhythmics ICD Code : Y52.2
International- Bretylium. Why it is prescribed (Indications) :
This medication is an antiarrhythmic agent, prescribed for ventricular fibrillation and life-threatening ventricular arrhythmia. It blocks the release of noradrenaline from nerve system. When it is not to be taken (Contraindications):
Dosage & When it is to be taken :
Life-Threatening Ventricular Arrhythmias- Adults- IV- The recommended dose is 5 to 10 mg/kg.
Children- IV- 50mg/kg/dose followed by 10mg/kg at 10 to 30 min intervals. How it should be taken :
It comes as a solution for injection to be administered by a healthcare provider. Warnings and Precautions :
* Caution should be exercised in patients with history of low or high blood pressure, severe heart disease, blocked blood vessels, lung, liver or kidney disease, children, during pregnancy and breastfeeding.
* It may cause dizziness and lightheadedness, get up slowly from bed. Side Effects :
Heart - Low blood pressure, slow heart rate, increased premature ventricular contractions and abnormal heart rhythm, high blood pressure, chest pain and sensation of substernal pressure.
Central Nervous System - Dizziness, lightheadedness, fainting, anxiety and vertigo.
Gastrointestinal - Nausea and vomiting after rapid IV injection, diarrhea and abdominal pain.
* Avoid excess dosage. Storage Conditions :
Store it at room temperature (25°C).
Comment & Contribute
Ask an Expert