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Brentuximab Vedotin
Latest prescription information about Brentuximab Vedotin. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Brentuximab Vedotin
Pronunciation : bren-TUX-i-mab
Therapeutic Classification : Chemotherapy
ICD Code : Y43.3
Trade Name(s): International- Adcetris. Why it is prescribed (Indications) : This medication is a monoclonal antibody, prescribed for certain types of lymphoma (Hodgkin lymphoma, systemic anaplastic large cell lymphoma [sALCL]). It works by killing cancer cells. When it is not to be taken (Contraindications): Hypersensitivity.
Dosage & When it is to be taken : IV- The recommended dose is 1.8 mg/kg, over 30 minutes infusion every 3 weeks. How it should be taken : It comes as a solution for injection, to be administered by a healthcare provider into the vein. Warnings and Precautions : * Caution should be exercised in patients with history of nerve problem, any allergy, who are taking other medications, during pregnancy and breastfeeding. * It may cause dizziness, do not drive a car or operate machinery while taking this medication. * It may decrease platelet counts; avoid injury or bruising. * Avoid contact with people who have infections that may spread to others. * Patient may develop with increased risk of tumor lysis syndrome (TLS), and viral brain infection (fatal conditions) with the following symptoms: irregular heartbeat, fainting, decreased urination, muscle weakness or cramps, dizziness, difficulty in talking, poor eyesight, nausea, vomiting, diarrhea, or loss of appetite; if it is so consult with your healthcare provider. Side Effects : Most Common - Decrease in white blood cells, anemia, peripheral sensory neuropathy, fatigue, nausea, fever, rash, diarrhea and pain. Blood - Swelling of lymph nodes and decrease in platelet counts. Central Nervous system - Headache, sleeplessness, anxiety and dizziness. General - Chills and swelling in the extremities. Infections - Upper respiratory tract infection. Gastrointestinal - Abdominal pain, vomiting and constipation. Skin - Itching, hair loss, night sweats and dry skin. Respiratory - Cough, difficulty in breathing and throat pain. Musculoskeletal - Joint pain, muscle pain, back pain and muscle spasms. Metabolic - Decreased appetite and weight. * Avoid excess dosage. Storage Conditions : Store vial at 2-8°C. |
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Reference
- Food and Drug Administration (FDA)
- National Institutes of Health (NIH)
- PubMed
- CIMS
- Indian Pharma Reference Guide 2012
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