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Generic Name : Boceprevir
Therapeutic Classification : Antivirals
ICD Code : Y41.5
♦ Safety Labeling Changes Approved By FDA
Trade Name(s): International- Victrelis. Why it is prescribed (Indications) : This medication is a protease inhibitor, prescribed for chronic hepatitis C. It decreases the amount of hepatitis C virus (HCV) in the body. When it is not to be taken (Contraindications): Contraindicated in pregnant women, co-administration with drugs highly dependent on CYP3A4/5, Adrenoreceptor antagonist, Anticonvulsants, Ergot derivatives, HMG-CoA reductase inhibitors, PDE5 enzyme Inhibitor, Sedative/Hypnotics, St. John's Wort, rifampin, cisapride, and in people with known hypersensitivity.
Dosage & When it is to be taken : Adult- PO- The recommended dose is 800 mg (four 200-mg capsules) three times daily (every 7-9 hours) with food. How it should be taken : It comes as a capsule to take by mouth, with food. Warnings and Precautions : * Caution should be exercised in patients with history of HIV/AIDS, liver or kidney impairment, Hepatitis B, cirrhosis, organ transplantation, anemia, children, during pregnancy and breastfeeding. Side Effects : Most Common - Fatigue, anemia, nausea/vomiting, headache, and sensory loss. ♦ Blood - Decrease in white blood cells and anemia. Gastrointestinal - Taste disorders, diarrhea and dry mouth. General - Fatigue, chills and weakness. Metabolic - Decreased appetite. Musculoskeletal - Joint pain. Central Nervous System - Dizziness, sleeplessness and irritability. Respiratory - Difficulty in breathing. ♦ Skin - Hair loss, dry skin, rash, angioedema, and urticaria. * Avoid excess dosage. Storage Conditions : Store it in refrigerator (2-8°C). Do not freeze it. |
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