Generic Name : Boceprevir Therapeutic Classification : Antivirals ICD Code : Y41.5♦ Safety Labeling Changes Approved By FDA
International- Victrelis. Why it is prescribed (Indications) :
This medication is a protease inhibitor, prescribed for chronic hepatitis C. It decreases the amount of hepatitis C virus (HCV) in the body. When it is not to be taken (Contraindications):
Contraindicated in pregnant women, co-administration with drugs highly dependent on CYP3A4/5, Adrenoreceptor antagonist, Anticonvulsants, Ergot derivatives, HMG-CoA reductase inhibitors, PDE5 enzyme Inhibitor, Sedative/Hypnotics, St. John's Wort, rifampin, cisapride, and in people with known hypersensitivity.
Dosage & When it is to be taken :
Adult- PO- The recommended dose is 800 mg (four 200-mg capsules) three times daily (every 7-9 hours) with food. How it should be taken :
It comes as a capsule to take by mouth, with food. Warnings and Precautions :
* Caution should be exercised in patients with history of HIV/AIDS, liver or kidney impairment, Hepatitis B, cirrhosis, organ transplantation, anemia, children, during pregnancy and breastfeeding. Side Effects :
Most Common - Fatigue, anemia, nausea/vomiting, headache, and sensory loss.
♦ Blood - Decrease in white blood cells and anemia.
Gastrointestinal - Taste disorders, diarrhea and dry mouth.
General - Fatigue, chills and weakness.
Metabolic - Decreased appetite.
Musculoskeletal - Joint pain.
Central Nervous System - Dizziness, sleeplessness and irritability.
Respiratory - Difficulty in breathing.
♦ Skin - Hair loss, dry skin, rash, angioedema, and urticaria.
* Avoid excess dosage. Storage Conditions :
Store it in refrigerator (2-8°C). Do not freeze it.
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