Bleomycin - Drug Information

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General Information on Bleomycin

Generic Name : Bleomycin

Pronunciation : blee oh mye' sin

Latest prescription information about Bleomycin. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.

Why is Bleomycin Prescribed? (Indications)

This medication is an anti – cancer agent, used for the treatment of skin, oral cavity, head and neck cancer. It is also used for lymphomas, cancer of the testis and fluid accumulation in the chest caused by cancer. 

When should Bleomycin not to be taken? (Contraindications)

Contraindicated in patients with hypersensitivity, severe lung disease, during pregnancy and lactation.

Pregnancy Category

A B C D X

Category D :

There is an evidence of fetal risk based on adverse reaction data, but potential benefits may allow the drug to be used in pregnant women despite risks.

What is the dosage of Bleomycin?

The recommended dose is 0.25 to 0.5units/kg (10 to 20 units/mē) once in a week, or twice.

How should Bleomycin be taken?

It comes as a solution for injection, administered into the large muscle, vein or under the skin.

What are the warnings and precautions for Bleomycin?

• Caution needed for patients with history of lung infection, pre-existing lung function impairment, kidney impairment, patients who received radiotherapy, particularly to the thorax.
• Regular chest x-rays should be done. Discontinue treatment if chest x-rays show infiltrates.

What are the side effects of Bleomycin?

•  Respiratory: Difficulty in breathing, lung disease and cracking sound.
•  Heart: Low blood pressure, cerebral arteritis, stroke, heart attack, Raynaud phenomenon(condition where there is spasm of blood vessels mainly in fingers and toes) and thrombotic microangiopathy, (clot formation in small blood vessels) (with combination chemotherapy).
•  Central Nervous System: Uneasiness.
•  Skin: Hair loss, redness, thickening of the skin, darkening of skin, nail changes, itching, rash, skin tenderness, mouth ulcer, stretch marks, blistering and scleroderma-like skin changes.
•  Gastrointestinal: Loss of appetite and vomiting.
•  Local: Pain, pain at tumor site and inflammation of veins.
•  Metabolic: Weight loss.
•  Miscellaneous: Allergic reactions.

What are the other precautions for Bleomycin?

Avoid excess dosage.
Use a reliable birth control method to prevent pregnancy.

What are the storage conditions of Bleomycin?

Injection: Refrigerate at 2-8°C. Do not freeze it.


Schedule : G

Drugs that are to be used only under medical supervision.

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