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Bleomycin

Latest prescription information about Bleomycin. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Bleomycin
Pronunciation : blee oh mye' sin
Therapeutic Classification : Chemotherapy
Trade Name(s): 
India- Bledmax Inj, Bleochem Vial, Bleocin Inj, Bleocip Vial, Bleolem Vial, Bleonco Vial, Bleostar-S Vial, Bleotex Vial, Naprobleo Vial, Oil Bleo Vial, Oncobleo Inj.
International-Blenoxane.
Why it is prescribed (Indications) : 
This medication is an anti – cancer agent, used for the treatment of skin, oral cavity, head and neck cancer. It is also used for lymphomas, cancer of the testis and fluid accumulation in the chest caused by cancer.

When it is not to be taken (Contraindications): 


Contraindicated in patients with hypersensitivity, severe lung disease, during pregnancy and lactation.

Pregnancy Category :

A B C D X
Category D : There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


When it is to be taken : 
The recommended dose is 0.25 to 0.5units/kg (10 to 20 units/m²) once in a week, or twice.
How it should be taken : 
It comes as a solution for injection, administered into the large muscle, vein or under the skin.
Special Instruction : 
*Caution needed for patients with history of lung infection, pre-existing lung function impairment, kidney impairment, patients who received radiotherapy, particularly to the thorax.
*Regular chest x-rays should be done. Discontinue treatment if chest x-rays show infiltrates.
Side Effects : 
Respiratory- Difficulty in breathing, lung disease and cracking sound.
Heart- Low blood pressure, cerebral arteritis, stroke, heart attack, Raynaud phenomenon(condition where there is spasm of blood vessels mainly in fingers and toes) and thrombotic microangiopathy, (clot formation in small blood vessels) (with combination chemotherapy).
Central Nervous System- Uneasiness.
Skin- Hair loss, redness, thickening of the skin, darkening of skin, nail changes, itching, rash, skin tenderness, mouth ulcer, stretch marks, blistering and scleroderma-like skin changes.
Gastrointestinal- Loss of appetite and vomiting.
Local- Pain, pain at tumor site and inflammation of veins.
Metabolic- Weight loss.
Miscellaneous- Allergic reactions.
Other Precautions : 
*Avoid excess dosage.
* Use a reliable birth control method to prevent pregnancy.
Storage Conditions : 
Injection: Refrigerate at 2-8°C. Do not freeze it.

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