This medication is an anticoagulant (thrombin inhibitor), prescribed for preventing blood clots in patients with unstable angina undergoing percutaneous transluminal coronary angioplasty ((PTCA) procedure to open blocked arteries).
Contraindicated in patients with major bleeding and hypersensitivity.
IV- The recommended bolus dose is 0.75 mg/kg, followed by an infusion of 1.75 mg/kg/h for the duration of the PCI/PTCA procedure.
It comes as a solution to be administered by a healthcare provider into the vein. After 5 minutes of administration, activated clotting time (ACT) test should be performed.
• Caution should be exercised in patients with history of heart disease, kidney disease or a bleeding or blood clotting disorder, any allergy, elderly, children, during pregnancy and breastfeeding.
• It may cause bleeding or bruising, avoid injury.
• Avoid alcohol consumption.
Low/high blood pressure and slow heart rate.
• Gastrointestinal : Nausea, vomiting and indigestion.
• Genitourinary: Urinary retention.
• Miscellaneous: Back pain, headache, injection site pain, sleeplessness, pelvic pain, anxiety, abdominal pain, fever and nervousness.
Avoid excess dosage.
Store it at controlled room temperature (20-25°C).
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