Why it is prescribed :
This medication is an anticoagulant (thrombin inhibitor), prescribed for preventing blood clots in patients with unstable angina undergoing percutaneous transluminal coronary angioplasty ((PTCA) procedure to open blocked arteries).
When it is not to be taken (Contraindications):
Contraindicated in patients with major bleeding and hypersensitivity.
Category B :
Animal studies have failed to demonstrate a risk to the fetus and appropriate studies on pregnant women are lacking.
Dosage & When it is to be taken (Indications):
IV- The recommended bolus dose is 0.75 mg/kg, followed by an infusion of 1.75 mg/kg/h for the duration of the PCI/PTCA procedure.
How it should be taken :
It comes as a solution to be administered by a healthcare provider into the vein. After 5 minutes of administration, activated clotting time (ACT) test should be performed.
Warnings and Precautions :
Caution should be exercised in patients with history of heart disease, kidney disease or a bleeding or blood clotting disorder, any allergy, elderly, children, during pregnancy and breastfeeding.
It may cause bleeding or bruising, avoid injury.
Avoid alcohol consumption.
Side Effects :
Low/high blood pressure and slow heart rate.
Nausea, vomiting and indigestion.
Back pain, headache, injection site pain, sleeplessness, pelvic pain, anxiety, abdominal pain, fever and nervousness.
Other Precautions :
Avoid excess dosage.
Storage Conditions :
Store it at controlled room temperature (20-25°C).