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Biperiden

Latest prescription information about Biperiden. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Biperiden
Pronunciation : bye PEAR i den
Therapeutic Classification : Antiparkinson Agents
ICD Code : Y46.7
Trade Name(s): 
International- Akineton.
Why it is prescribed (Indications) : 
This medication is an anticholinergic agent, prescribed for Parkinson disease and involuntary muscle movement due to neuroleptic drug therapy. 
When it is not to be taken (Contraindications): 
Contraindicated in patients with increased eye pressure, bowel obstruction and abnormal dilation of the colon; known hypersensitivity to biperiden.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : 
Parkinson's disease: Oral: The usual beginning dose is one tablet three or four times daily. The dosage should be individualized with the dose titrated upward to a maximum of 8 tablets (16 mg) per 24 hours.
Drug-induced Extra pyramidal symptoms- Oral: One tablet one to three times daily.
How it should be taken : 
It comes as a tablet to take by mouth, with food.
Warnings and Precautions : 
* Caution should be exercised in patients with history of prostate enlargement, allergies, urinating problem, epilepsy, heart disease, depression, kidney or liver disease, children, during pregnancy and breastfeeding.
* It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.
* Avoid alcohol consumption.
Side Effects : 
Most Common- Drowsiness, dizziness, headache, loss of appetite, blurred vision, agitation, postural hypotension, stomach upset, vision changes, sleeplessness, trembling of the hands and dry mouth.
Gastrointestinal - Gastric irritation, nausea, vomiting and increased salivation.
Central Nervous System - Disorientation, confusion and disturbed behavior.
Genitourinary - Urinary retention.
Heart - Decreased heart rate.
Other Precautions : 
* Heatstroke may occur, avoid strong sunlight.
Storage Conditions : 
Store it at room temperature (25°C), and in an airtight container.

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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