Generic Name : Bicalutamide Pronunciation : bye ka LOO ta mide
India- Biprosta Tab, Caludec Tab, Caluran Tab, Calutide-50 Film-Coated Tab, Casodex Tab, Cosalon Tab, Utamide Tab.
International- Casodex. Why it is prescribed (Indications) :
This medication is a non-steroidal anti-androgen, prescribed for prostate cancer. It blocks testosterone action. When it is not to be taken (Contraindications):
Contraindicated in women, lactation, pregnancy; hypersensitivity.
Dosage & When it is to be taken :
Adult: PO- 50 mg (1 tablet) once daily at the same time of day with or without food. How it should be taken :
It comes as a tablet to take by mouth, with or without food. Warnings and Precautions :
* Monitor liver function regularly.
* Monitor serum level of prostate specific antigen (PSA) regularly, to evaluate patient's clinical progress.
* It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.
Side Effects :
Body as a Whole- Pain (general), back pain, weakness, pelvic pain, infection, abdominal pain, chest pain headache, flu like syndrome, fever and chills.
Heart- Hot flashes, high blood pressure, chest pain and congestive heart failure.
Gastrointestinal- Constipation, nausea, diarrhea, increased liver enzyme, indigestion, flatulence, loss of appetite, vomiting, blood in stool, dry mouth, difficulty in swallowing and gastrointestinal disorder.
Metabolic- Swelling in the extremities, weight loss, increased blood sugar level, weight gain, blood urea nitrogen and dehydration.
Musculoskeletal - Muscle/joint pain, leg cramps and fractures.
Central Nervous System- Dizziness, drowsiness, tingling, sleeplessness, anxiety, confusion, decreased libido, nervousness and depression.
Respiratory - Difficulty in breathing, increased cough, inflammation of pharynx/bronchus/nose/sinus, asthma and nosebleed.
Skin - Rash, sweating, dry skin, hair loss, itching and skin cancer.
Genitourinary- Blood in urine, urinary tract infection, breast enlargement in male, impotence, painful urination, breast pain, increased urinary frequency, urinary retention and urinary incontinence.
* Limit the intake of alcoholic beverages.
Storage Conditions :
Oral: Store it at controlled room temperature (30°C).
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