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Generic Name : Bevacizumab
Pronunciation : be va siz' yoo mab
Trade Name(s):
International- Avastin. This medication is used to cure certain types of advanced lung cancer. It is also used to treat certain types of brain, breast, kidney, colon, or rectal cancer along with other cancer medicines. When it is not to be taken (Contraindications):
When it is to be taken : Metastatic Carcinoma of the Colon or Rectum - Adults IV infusion 5 or 10 mg/kg every 14 days in combination with IV 5-fluorouracil�based chemotherapy. The recommended dosage is 5 mg/kg every 14 days when administered with irinotecan/5-fluorouracil/leucovorin, and 10 mg/kg every 14 days when administered with 5-fluorouracil/leucovorin/oxaliplatin. How it should be taken : This medication available in the form of injection, administered by health care provider, intravenously. It is usually given once every 14 days to treat breast cancer or cancer of the colon or rectum and once every 3 weeks to treat lung cancer Special Instruction : *It may reduce the number of clot-forming cells (platelets) in your blood. Avoid injuries. *Caution should be exercised in patients with history of cancer and heart disease, during pregnancy and lactation. Side Effects : Gastrointestinal- Changes in taste, constipation, diarrhea, increased thirst, indigestion, loss of appetite, mouth pain or sores, nausea, vomiting, black, tarry stools and dry mouth. Central Nervous System- Dizziness, tiredness and headache. Skin- Dry skin, hair loss, swelling, or redness at the injection site, rash, hives, itching and swelling of the mouth, face, lips, or tongue. Eye and ENT- Nosebleed, stuffy or runny nose and voice changes. Heart- Difficulty breathing, tightness in the chest, calf pain or tenderness and chest pain. Miscellaneous- Muscle pain, sluggishness, weakness and weight loss. * Do not administer or mix bevacizumab with dextrose solutions. Storage Conditions : It is normally handled and stored by healthcare providers. |
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