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Benserazide

Latest prescription information about Benserazide. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Benserazide
Pronunciation : ben-SAIR-uh-zide
Trade Name(s): 
India- Manopar, Madopar, Benspar.
International- Prolopa- Levodopa+Benserazide.
Why it is prescribed (Indications) : 
This medication is a peripherally-acting aromatic L-amino acid decarboxylase (AAAD) or DOPA decarboxylase inhibitor, prescribed for Parkinson's syndrome. 
When it is not to be taken (Contraindications): 
Hypersensitivity.

Pregnancy Category :

A B C D X
Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Dosage & When it is to be taken : 
PO- Per cap contains levodopa 100 mg and benserazide 25 mg: Initial: 1 cap 1-2 times/day. May increase if needed. Max: 12 caps/day.
How it should be taken : 
It comes as a capsule to take by mouth, with food.
Warnings and Precautions : 
* Caution should be exercised in patients with history of unexplained skin spots, kidney disease, liver disease, heart disease, ulcers, stomach problems, increased eye pressure, psychiatric illness, depression, any allergy, during pregnancy and breastfeeding.
Side Effects : 
Flushing, headache, hand tremor, stomach upset, dry mouth, hiccups, blurred vision, change in sexual desire, weight changes, sweating and moodiness.
Other Precautions : 
*Avoid excess dosage.
Storage Conditions : 
Store it at room temperature.

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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