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Belladonna Alkaloid Combinations and Phenobarbital

Latest prescription information about Belladonna Alkaloid Combinations and Phenobarbital. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Belladonna Alkaloid Combinations and Phenobarbital
Pronunciation : bell a don' a- fee noe bar' bi tal
Therapeutic Classification : Antispasmodics / Gi Motility
ICD Code : Y55.1
Trade Name(s): 
International- Donnatal and Hyosophen.
Why it is prescribed (Indications) : 
This medication is an anticholinergic and barbiturate combination, prescribed for Irritable Bowel Syndrome and intestinal inflammation. 
When it is not to be taken (Contraindications): 
Contraindicated in patients with increased eye pressure, gastrointestinal obstruction, urinary obstruction, heart problem with severe bleeding, muscle problem, alcohol abuse, history of excitement after taking phenobarbital drugs and hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : 
Dose is based on patient’s condition.
The recommended dose is one tablet every twelve (12) hours.
How it should be taken : 
It comes as a tablet to take by mouth, 30 minutes before meals and at bedtime.
Warnings and Precautions : 
* Caution should be exercised in patients with history of nerve problems, prostate problems, heart problems, hernia, diarrhea, fever, kidney or liver problems, gallbladder problems, breathing problems, overactive thyroid, high blood pressure, difficulty in urinating, ulcer, depression, suicidal thoughts, shock, alcohol addiction, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.
* It may cause dizziness, drowsiness, blurred vision or lightheadedness, do not drive a car or operate machinery while taking this medication.
* Avoid alcohol consumption.
Side Effects : 
Gastrointestinal - Dry mouth, nausea, vomiting, constipation and abdominal bloating.
Heart - Fast heart rate and palpitations.
Central Nervous System - Headache, dizziness, sleeplessness, excitement, agitation, drowsiness, nervousness and weakness.
Eye and ENT - Increased eye pressure, blurred vision, dilation of the pupils and loss of taste.
Genitourinary - Impotence, suppression of lactation, urinary hesitancy and retention.
Miscellaneous Musculoskeletal pain, severe allergic reactions including anaphylaxis, hives and other skin manifestations and decreased sweating.
Other Precautions : 
* Avoid becoming over heated; otherwise it may lead to heatstroke.
* It may cause photosensitivity; wear sunglasses.
Storage Conditions : 
Store it at 20-25°C.


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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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