Generic Name : Belatacept Pronunciation : bel-AT-a-sept Therapeutic Classification : Immunological Agents
International- Nulojix. Why it is prescribed (Indications) :
This medication is a fusion protein, prescribed for preventing organ rejection in kidney transplantation along with other medications. When it is not to be taken (Contraindications): Contraindicated in patients who are Epstein-Barr Virus (EBV) seronegative or with unknown EBV serostatus and hypersensitivity.
Dosage & When it is to be taken :
IV- Initial phase dosing: 10 mg/kg on day of transplant (prior to implantation); repeat this dose on Day 5 and at end of Weeks 2, 4, 8, and 12 after transplantation. How it should be taken :
It comes as a powder for injection (diluted with fluid), to be administered by a healthcare provider into the vein. Warnings and Precautions :
* Caution should be exercised in patients with history of blood cell problems, blood electrolyte problems, diabetes, high blood pressure, cancer, recent vaccination, tuberculosis, who are taking other medications, any allergy, children, during pregnancy and breastfeeding.
* It may cause dizziness, do not drive a car or operate machinery while taking this medication.
* Avoid contact with people who have any infection, which may spread to others.
* Patient may develop with increased risk of skin cancer; so avoid exposure to sunlight, use of sunscreen lotion. Side Effects :
Infections Urinary tract infection, upper respiratory infection, lung infection.
Gastrointestinal - Diarrhea, constipation, nausea, vomiting, abdominal pain.
Metabolic - Decrease or increase in blood minerals.
General - Fever, swelling in the extremities. Blood - Anemia, decrease in white blood cells.
Genitourinary - Blood in urine, painful urination, and kidney tubule cells damage.
Heart - High blood pressure, low blood pressure.
Respiratory - Cough, difficulty in breathing.
Investigations - Increased blood creatinine.
Musculoskeletal - Joint pain, back pain.
* Avoid excess dosage. Storage Conditions :
Store the medication as directed by your physician.
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