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Generic Name : Azathioprine
Therapeutic Classification : antirheumatics
Trade Name(s):
India- Azap Tab, Azathioprine Tab, Azimune Tab, Azoprine Tab, Azoran Tab, Imuran Tab, Imuzat Tab, Transimune Tab, Zymurine Tab. International- Azasan and Imuran. This medication is an immunosuppressant, prescribed for prevention of rejection kidney transplantation. It is also used for rheumatoid arthritis and autoimmune diseases. When it is not to be taken (Contraindications):
When it is to be taken : Adult: PO- Rheumatoid arthritis Initial: 1 mg/kg/day for 6-8 wk. May adjust dose gradually to 2.5 mg/kg/day if needed. Prevention of rejection in organ and tissue transplantation -1-5 mg/kg/day. Auto-immune diseases -1-3 mg/kg/day. IV -Renal homotransplantation- Usual initial: 3-5 mg/kg/day beginning at the time of transplantation. Maintenance: 1-3 mg/kg/day. How it should be taken : It comes as a tablet to take by mouth, with food. Special Instruction : * Caution should be exercised in patients with history of kidney or liver problems, gout, any infection, anemia, bone marrow depression, any allergy, who are taking other medications and children. * Avoid contact with people with infections. * It may reduce platelet counts; avoid injury or bruising. * Patient may experience severe nausea and vomiting; if it so consult with your doctor. * Patient may develop with increased risk of cancer; if you notice any unusual growth or tumor consult with your doctor immediately. Side Effects : Blood - Decreased white blood cells and platelets. Gastrointestinal - Nausea, vomiting, diarrhea and abdominal pain. Miscellaneous - Rash, hair loss, fever, joint pain, diarrhea, negative nitrogen balance and reversible interstitial lung inflammation. * Monitor complete blood counts, liver function, and TPMT enzyme activity, while taking this medication. * Avoid excess dosage. Storage Conditions : Store it at room temperature and in an airtight container, keep away from children. |
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