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Autologous Cultured Chondrocytes

Latest prescription information about Autologous Cultured Chondrocytes. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Autologous Cultured Chondrocytes
Pronunciation : KON-droe-sites, aw-TALL-oh-gus KUL-cherd
Therapeutic Classification : Musculoskeletal Agents
Trade Name(s): 
International- Carticel.
Why it is prescribed (Indications) : 
This medication is an autologous (using the patient's own cells) cellular product, prescribed for the repair of symptomatic cartilage defects of the femoral condyle. 
When it is not to be taken (Contraindications): 
Contraindicated in patients with known hypersensitivity to gentamicin.

Dosage & When it is to be taken : 
Cell doses per cm² of defect- 0.64 million to 3.3 million cells/cm
How it should be taken : 
It comes as a vial, which contains approximately 12 million cells, should be inserted into the affected area.
Warnings and Precautions : 
* Caution should be exercised in people who are at risk of infections, children, pregnant and breastfeeding women.
Side Effects : 
Interventions during subsequent surgical procedures- Surgical removal of cartilage lesion, scars, surgical removal of joint tissue, surgery of the cartilage, removal of a torn meniscus (common knee joint injury), microfracture, scar tissue removal, hardware removal, joint surgeries.
Most Serious - Injury complications, graft overgrowth, knee pain, cartilage injury, graft complication, meniscal lesion, graft failure, joint inflammation.
Other Precautions : 
Storage Conditions : 
Store it at room temperature. Do not freeze.

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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