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Atovaquone

Latest prescription information about Atovaquone. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Atovaquone
Pronunciation : a toe' va kwone
Therapeutic Classification : Miscellaneous Anti- Infectives
ICD Code : Y41
Trade Name(s): 
International- Mepron.
Why it is prescribed (Indications) : 
This medication is an antibiotic, prescribed for Pneumocystis pneumonia (PCP), Toxoplasmosis and also for malaria treatment in combination with proguanil. The medication inhibits the reproduction of the protozoan that causes the disease.  
When it is not to be taken (Contraindications): 
Hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : 
Adult: The recommended oral dose is 1,500 mg (10 ml) once daily, administered with a meal.
How it should be taken : 
It comes as a suspension to take by mouth with food.
Warnings and Precautions : 
* Caution should be exercised in patients with history of stomach, intestinal problem, lung disease, liver impairment, allergy, elderly, children, during pregnancy and breastfeeding.
Side Effects : 
Most Common- Allergic reactions like rash, fever, sore throat, nausea, vomiting, increased cough and anemia.
Central Nervous System- Headache, weakness, dizziness, depression, anxiety and sleeplessness.
Gastrointestinal- Abdominal pain.
Respiratory- Difficulty in breathing and inflammation of nose.
Miscellaneous- Flu-like syndrome, itching and muscle pain.
Other Precautions : 
*Take full course of treatment.
Storage Conditions : 
Store it at room temperature, and in an airtight container. Keep away from children.


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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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