Trade Names/Brand Names :
Why it is prescribed :
This medication is an HMG-CoA reductase inhibitor, also known as "statin”, prescribed for hyperlipidemia.
When it is not to be taken (Contraindications):
Contraindicated in patients with severe liver problems, who are taking HIV protease inhibitors, during pregnancy and breastfeeding, and hypersensitivity.
Category X :
Animal and/or human studies have demonstrated fetal injury and potential risks outweigh the benefits of the drug in pregnancy. These drugs are found to be harmful when taken during pregnancy, and should not be used.
Dosage & When it is to be taken (Indications):
Adult PO- Initial- The recommended dose is 10 mg daily. Maximum: 80 mg/day.
How it should be taken :
It comes as a tablet to take by mouth, with or without food.
Warnings and Precautions :
• Caution should be exercised in patients with history of low blood pressure, serious infection, seizures, electrolyte problems, liver problems, alcohol abuse, any allergy, during pregnancy and breastfeeding.
It may cause dizziness, do not drive a car or operate machinery while taking this medication.
Avoid alcohol consumption.
Follow the diet and exercise program as directed by your physician.
Monitor blood cholesterol level and liver functions regularly while taking this medication.
Side Effects :
• Most Common
Nose inflammation, joint pain, diarrhea, pain in extremity, urinary tract infection, indigestion, nausea, muscle and bone pain, muscle spasms, sleeplessness and throat pain.
• Body as a whole
Uneasiness and fever.
Abdominal discomfort, eructation, flatulence, liver inflammation and bile obstruction.
Muscle fatigue, neck pain and joint swelling.
Increase in liver enzymes level, abnormal liver function tests and increased sugar level.
• Central Nervous system
Dizziness, depression, fatigue, peripheral neuropathy
and abnormal dreams.
• Eye and ENT
Blurred vision and ringing in the ear.
Urinary tract infection.
Immune-mediated necrotizing myopathy (IMNM).
Other Precautions :
Avoid excess dosage.
Storage Conditions :
Store it at room temperature (25°C).
♦ Safety Labeling Changes Approved By FDA