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Asenapine

Latest prescription information about Asenapine. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Asenapine
Pronunciation : a-SEN-a-peen
Trade Name(s): 
International- Saphris.
Why it is prescribed (Indications) : This medication is an atypical antipsychotic agent, prescribed for schizophrenia and acute mania with bipolar disorder.

When it is not to be taken (Contraindications): 

Contraindicated in patients with severe liver problems, heart diseases, who are taking antiarrhythmic, antipsychotic, phenothiazine, quinolone drugs and hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


When it is to be taken : Sublingual- The recommended starting and target dose is 5 mg given twice daily.
How it should be taken : It comes as a tablet to be placed under the tongue, with or without food.
Special Instruction : 
* Caution should be exercised in patients with history of high blood pressure, cancer, Alzheimer disease, dementia, Parkinson disease, or esophagus problems, low blood volume, alcoholism, heart, liver, and kidney diseases, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.
* It may cause drowsiness, dizziness, or lightheadedness, do not drive a car or operate machinery and get up slowly from bed while taking this medication.
* Avoid alcohol consumption.
* Avoid abrupt withdrawal; withdraw gradually.
* Monitor complete blood cell counts, electrolyte levels, or fasting blood sugar levels regularly while taking this medication.
* Patient may develop with increased risk of neuroleptic malignant syndrome (NMS) with the following symptoms: fever; stiff muscles; confusion; abnormal thinking; fast or irregular heartbeat; and sweating. If it is so consult with your doctor.
* Avoid contact with people who have infections.
* Drink adequate fluid; otherwise it may lead to dehydration.
Side Effects : 
Most Common - Brain disorder, movement disorder, weight increased and drowsiness.
Gastrointestinal - Constipation, dry mouth, motionless, increased saliva, stomach discomfort and vomiting.
General - Fatigue and irritability.
Metabolic - Increased appetite.
Central Nervous system - Weakness, dizziness and sleeplessness.
Heart - High blood pressure.
Other Precautions : 
* Avoid excess dosage.
* It may affect blood sugar level; monitor sugar level regularly while taking this medication.
Storage Conditions : 
Store it at room temperature (25°C).

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