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Generic Name : Aprepitant
Pronunciation : ap-RE-pi-tant
Therapeutic Classification : antiemetics
Trade Name(s):
India- Aprecap, Aprelief, Apretero, Empov. International- Emend. This medication is an antiemetic, prescribed for prevention of acute and delayed chemotherapy-induced nausea and vomiting (CINV) and for prevention of postoperative nausea and vomiting. When it is not to be taken (Contraindications):
When it is to be taken : PO- The recommended dose is 125 mg, 1 hour prior to chemotherapy treatment (Day 1) and 80 mg orally once daily in the morning on Days 2 and 3. How it should be taken : It comes as a capsule to take by mouth, with or without food. Special Instruction : * Caution should be exercised in patients with history of nausea or vomiting, liver disease, any allergy, who are taking other medications, during pregnancy and breastfeeding. * It may cause dizziness, do not drive a car or operate machinery while taking this medication. * Avoid alcohol consumption. Side Effects : Body as a Whole - Weakness/fatigue, dizziness, dehydration, abdominal pain and fever. Gastrointestinal - Nausea, constipation, diarrhea, vomiting, heartburn and stomach discomfort. ENT - Ringing in the ear. Blood - Decrease in white blood cells. Metabolic - Loss of appetite. Central Nervous System - Headache and sleeplessness. Respiratory - Hiccups. * Avoid excess dosage. Storage Conditions : Store it at room temperature (20-25°C). |
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