Generic Name : Anakinra Pronunciation : an-ah-KIN-rah Therapeutic Classification : Antirheumatics ICD Code : Y45.4
International- Kineret. Why it is prescribed (Indications) :
This medication is a recombinant human interleukin 1 antagonist, prescribed for reducing the pain and swelling associated with moderate to severe rheumatoid arthritis either alone or in combination with methotrexate. It inhibits the binding of the interleukin 1 to its receptor. When it is not to be taken (Contraindications):
Hypersensitivity to Escherichia coli -derived proteins, anakinra, or any component of product.
Dosage & When it is to be taken :
SC- The recommended dose is 100 mg/day. How it should be taken :
It comes as a solution for injection, administered subcutaneously by a healthcare provider once a day, at the same time every day. Warnings and Precautions :
*Avoid vaccination while taking this medication.
*Swelling or bruising at the injection site occurs; apply a cold pack on the injection site immediately after injection.
*It should not be used in children.
*Caution needed for patients with history of infection, asthma, HIV infection or AIDS, or kidney disease, during pregnancy and breast feeding.
*Do not reuse needles, syringes, or other materials. Side Effects :
Most Common- Injection site reactions such as redness, bruising, swelling, and pain, chest infection, worsening of condition, urinary tract infection, headache, nausea, diarrhea, sinusitis, joint pain, flu like-symptoms, and abdominal pain.
*Patient may experience a decrease in neutrophil counts, monitor complete blood count regularly. Storage Conditions :
Store it in refrigerator (2 to 8°C). Do not freeze it. Keep away from children.
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