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Amsacrine

Latest prescription information about Amsacrine. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Amsacrine
Therapeutic Classification : Chemotherapy
Trade Name(s): 
International- Amsidine, m-AMSA.
Why it is prescribed (Indications) : 
This medication is an antineoplastic agent, prescribed for certain types of lymphoma and acute adult leukemia. It is usually given in combination with other chemotherapy drugs.
When it is not to be taken (Contraindications): 
Hypersensitivity.

Dosage & When it is to be taken : 
IV- Adult: Induction: 90 mg/m2/day for 5-8 days, may increase to 120 mg/m2/day.
How it should be taken : 
It comes as a solution for injection to be administered by a healthcare provider into the vein.
Warnings and Precautions : 
* Caution should be exercised in patients with liver or kidney diseases, during pregnany and breastfeeding.
* Monitor complete blood counts, electrolyte for each treatment, heart, liver, kidney and CNS function regularly.
Side Effects : 
Most Common - Fatigue (tiredness), sore mouth and throat, loss of fertility, absence of menstrual period.
Miscellaneous - Hair loss, pain and swelling, inflammation at injection site, diarrhea.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store the medication as directed by your physician.

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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