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Generic Name : Amoxicillin and Clavulanate Potassium
Pronunciation : (a mox i sill' in) (klav' yoo la nate)
Trade Name(s):
India- Clavunate.
Why it is prescribed (Indications) :
This combination medication contains semisynthetic antibiotic amoxicillin and β-lactamase inhibitor, prescribed for lower respiratory infections, otitis media, sinusitis, urinary tract infections, and skin and skin Structure infections.
When it is not to be taken (Contraindications):
Contraindicated in patients with previous history of cholestatic jaundice/liver dysfunction, and hypersensitivity.
When it is to be taken :
Adults-
The usual adult dose is one amoxicillin and clavulanate potassium tablet, 500 mg/125 mg every 12 hours or one amoxicillin and clavulanate potassium tablet, 250 mg/125 mg every 8 hours.
How it should be taken :
It comes as a tablet and capsule to take by mouth, with or without food.
Special Instruction :
*Caution should be exercised in patients with history of liver or kidney disease, elderly, children, during pregnancy and breastfeeding.
*Avoid long-term use of this medication; otherwise it may cause secondary infection.
Side Effects :
Gastrointestinal-
Diarrhea, nausea, vomiting, indigestion, stomach inflammation, mouth ulcer and intestinal bleeding.
Hypersensitivity-
Skin rashes, itching, hives, angioedema and serum sickness-like reactions.
Liver-
Elevated liver enzyme levels.
Genitourinary-
Kidney inflammation, and blood in urine.
Central Nervous System-
Agitation, anxiety, behavioral changes, confusion, convulsion, dizziness, sleeplessness and reversible hyperactivity.
Other Precautions :
*Avoid excess dosage.
Storage Conditions :
Store it at room temperature and in an airtight container.
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