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Medindia » Medication Manual » Amoxicillin and Clavulanate Potassium

Amoxicillin and Clavulanate Potassium

Updated on : January - 2013

Latest prescription information about Amoxicillin and Clavulanate Potassium. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.

Generic Name : Amoxicillin and Clavulanate Potassium

Pronunciation : (a mox i sill' in) (klav' yoo la nate)

Therapeutic Classification : Antibiotics

ICD Code : Y40.0

Trade Name(s):
India- Clavunate.

Why it is prescribed (Indications) :
This combination medication contains semisynthetic antibiotic amoxicillin and β-lactamase inhibitor, prescribed for lower respiratory infections, otitis media, sinusitis, urinary tract infections, and skin and skin Structure infections.

When it is not to be taken (Contraindications):
Contraindicated in patients with previous history of cholestatic jaundice/liver dysfunction, and hypersensitivity.

♦ Pregnancy Category :

A B C D X

Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Dosage & When it is to be taken :
Adults- The usual adult dose is one amoxicillin and clavulanate potassium tablet, 500 mg/125 mg every 12 hours or one amoxicillin and clavulanate potassium tablet, 250 mg/125 mg every 8 hours.

How it should be taken :
It comes as a tablet and capsule to take by mouth, with or without food.

Warnings and Precautions :
*Caution should be exercised in patients with history of liver or kidney disease, elderly, children, during pregnancy and breastfeeding.
*Avoid long-term use of this medication; otherwise it may cause secondary infection.
♦ It may increase prothrombin time; monitor it regularly while taking this medication.

Side Effects :
Gastrointestinal- Diarrhea, nausea, vomiting, indigestion, stomach inflammation, mouth ulcer and intestinal bleeding.
Hypersensitivity- Skin rashes, itching, hives, angioedema and serum sickness-like reactions.
Liver- Elevated liver enzyme levels.
Genitourinary- Kidney inflammation, and blood in urine.
Central Nervous System- Agitation, anxiety, behavioral changes, confusion, convulsion, dizziness, sleeplessness and reversible hyperactivity.

Other Precautions :
*Avoid excess dosage.

Storage Conditions :
Store it at room temperature and in an airtight container.

♦ Safety Labeling Changes Approved By FDA

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Posted by: Bhashyam, India Posted on: 2/9/2013 My father has been consuming this clavam 625 past 15 dayz...is it for water or fluid filled in lungs....as the x-ray report which we tuk showed a blurred ribs on right or left hand syd....is it dangerous...how to treat it KINDLY HELP
Posted by: datta70, India Posted on: 1/30/2013 I have been prescribed Clavam 625mg 3 times a day for 5 days to treat pharyngitis. Doctor has warned about possible stomach complications and has advised becousules with the drug. While stomach problem is yet to develop (I am in 2nd day), I have developed dry cough (don't know if it is linked to Clavam).
Posted by: polu_prasad, India Posted on: 10/6/2012 My nephew who had ab·scess over left gluteal region was prescribed Amoxicillin and Clavulanate Potassium (625 mg three tablets a a day) tab. after taking tablets for a day he developed complication which included nausea, high Fever (for the next three day), headache, backache, multiple motion in a day etc. I think, doctors should be extra cautious in prescribing this medicine to patients.
Posted by: skylarkmak, India Posted on: 10/6/2012 PLESASE LET ME KNOW THE USES OF aMOXYCILLIN & POTASSIUM CLAVULANATE tABLETS ip 250 MG. pLEASE MAIL ME AT SKYLARKMAK@YAHOO.COM
Posted by: pkumar1965, India Posted on: 6/1/2012 I was down with mild fever and went to a hospital for treatment, where a doctor prescribed me clavidur 625 tab 3 times a day for five days + dolapar (paracetamol 500) + a vitamin c tab + Rabeprazole Sodium tab. Is it a recommended way of prescribing medicine to a patient with mild fever? After consuming this I am affected with many of the side effect mentioned above.Besides, I have developed problems like dry cough,headache and other such problems. I am still continuing this medicine as need to finish two more tablets as per doctor's advice. Please advise. Pramod,
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