Amobarbital - Drug Information

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General Information on Amobarbital

Generic Name : Amobarbital

Pronunciation : am- oh- bar'- bi- tal

Latest prescription information about Amobarbital. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y47.5 | Therapeutic Classification : ANXIOLYTICS, SEDATIVES AND HYPNOTICS

Trade Names/Brand Names of Amobarbital

International- Amytal.

Why is Amobarbital Prescribed? (Indications)

This medication is a barbiturate derivative, prescribed for anxiety, insomnia and induction of preanesthetic sedation.  It alters cerebellar function and produces drowsiness, sedation and hypnosis

When should Amobarbital not to be taken? (Contraindications)

Contraindicated in patients with history of acute or chronic pain, respiratory disease, severe liver impairment, porphyria and hypersensitivity.

Pregnancy Category

A B C D X

Category D :

There is an evidence of fetal risk based on adverse reaction data, but potential benefits may allow the drug to be used in pregnant women despite risks.

What is the dosage of Amobarbital?

Insomnia- Adults - PO/IM/IV 65 to 200 mg at bedtime.
Sedation- Adults - PO/IM/IV 30 to 50 mg twice daily or 3 times daily.
Children - PO/IM 2 to 6 mg/kg/dose.

How should Amobarbital be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein or large muscle.

What are the warnings and precautions for Amobarbital?

Caution should be exercised in patients with history of liver or kidney disease, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.
Avoid long-term use of this medication; otherwise patient may get addicted to this drug.
Avoid rapid administration; otherwise it may lead to breathing problem.
Avoid alcohol consumption.

What are the side effects of Amobarbital?

   Heart : Slow heart rate, low blood pressure and fainting.
   Central Nervous System : Drowsiness, agitation, confusion, headache, in coordination, CNS depression, excitement, abnormal dreams, mental disturbances, hallucinations, sleeplessness and dizziness.
   Gastrointestinal : Nausea, vomiting and constipation.
   Blood : Blood disorders.
   Liver : Liver damage.
   Respiratory : Shortness of breath, difficulty in breathing and asthma.
   Miscellaneous : Hypersensitivity reactions (eg, swelling, rashes, exfoliative dermatitis), fever and injection site reactions (eg, local pain, thrombophlebitis).

What are the other precautions for Amobarbital?

Avoid excess dosage.

What are the storage conditions of Amobarbital?

Store it at controlled room temperature (15 to 30C), and in an airtight container. Keep away from children.


Schedule : X

Narcotic and Psychotropic drugs which cannot be sold without the prescription of a Registered Medical Practitioner.

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