Medindia » Medication Manual » Altretamine

Altretamine

Latest prescription information about Altretamine. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
Email Email print Print Save this page Save Syndicate Syndicate
Generic Name : Altretamine
Pronunciation : ahl-TRETT-uh-meen
Therapeutic Classification : Chemotherapy
Trade Name(s): 
India- Cantret.
International- Hexalen.
Why it is prescribed (Indications) : 
This medication is an antineoplastic alkylating agent, prescribed for certain types of cancer such as ovarian cancer. It slows the cancer cells growth.
When it is not to be taken (Contraindications): 
Contraindicated in patients with preexisting severe bone marrow depression, and hypersensitivity.

Pregnancy Category :

A B C D X
Category D : There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : 
Adult- PO- It may be administered either for 14 or 21 consecutive days in a 28 day cycle at a dose of 260 mg/m²/day.
How it should be taken : 
It comes as a capsule to take by mouth, with food and at bedtime.
Warnings and Precautions : 
* Caution should be exercised in patients with history of bone marrow cancer, bone marrow depression, decrease in white blood cells, liver problem, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.
* It may reduce platelet counts; avoid injury or bruising.
Side Effects : 
Central Nervous System - Mood disorders, loss of consciousness, incoordination, dizziness and fainting.
Gastrointestinal - Nausea and vomiting.
Blood - Bone marrow depression.
Genitourinary - BUN- Blood urea nitrogen.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it at room temperature (25°C).

Comment & Contribute
Comments should be on the topic and should not be abusive. Comments are normally moderated and are reviewed after they are posted.
* Your comment can be maximum of 2500 characters
I agree to the terms and conditions
If you have a question about health related issues, you can now post it in our Ask An Expert section on our community website Medwonders.com and get answers from our panel of experts.

Browse the Drugs alphabetically

Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
Drugs Index
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z