Generic Name : Altretamine Pronunciation : ahl-TRETT-uh-meen
Therapeutic Classification : Chemotherapy Trade Name(s):
International- Hexalen. Why it is prescribed (Indications) :
This medication is an antineoplastic alkylating agent, prescribed for certain types of cancer such as ovarian cancer. It slows the cancer cells growth. When it is not to be taken (Contraindications):
Contraindicated in patients with preexisting severe bone marrow depression, and hypersensitivity.
Dosage & When it is to be taken :
Adult- PO- It may be administered either for 14 or 21 consecutive days in a 28 day cycle at a dose of 260 mg/m²/day. How it should be taken :
It comes as a capsule to take by mouth, with food and at bedtime. Warnings and Precautions :
* Caution should be exercised in patients with history of bone marrow cancer, bone marrow depression, decrease in white blood cells, liver problem, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.
* It may reduce platelet counts; avoid injury or bruising. Side Effects :
Central Nervous System - Mood disorders, loss of consciousness, incoordination, dizziness and fainting.
Gastrointestinal - Nausea and vomiting.
Blood - Bone marrow depression.
Genitourinary - BUN- Blood urea nitrogen.
* Avoid excess dosage. Storage Conditions :
Store it at room temperature (25°C).
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