Why it is prescribed :
This combination medication contains thiazolidinedione antidiabetic and DPP-4 inhibitor antidiabetic, prescribed for type 2 diabetes mellitus.
When it is not to be taken (Contraindications):
Contraindicated in patients who have severe heart failure, and known hypersensitivity.
Category C :
Animal studies have shown adverse effects on the fetus and there are no appropriate studies in pregnant women, but potential benefits may allow the use of the drug in pregnant women despite the potential for risks.
Dosage & When it is to be taken (Indications):
Dose is based on patient’s condition. Maximum recommended dose is 25/45mg.
How it should be taken :
It comes as a tablet, which contains 25 mg alogliptin and 15 mg pioglitazone to take by mouth, with or without food.
Warnings and Precautions :
Caution should be exercised in patients with history of heart failure, diabetic eye disease, eye swelling, kidney or liver impairment, bladder cancer, acute pancreatitis, fluid retention, fractures, hypoglycemia (abnormal decrease in blood sugar), premenopausal woman, any allergy, who are taking other medications, during pregnancy and breastfeeding.
Follow diet and exercise program as directed by your physician.
Monitor blood sugar level regularly while taking this medication.
Perform eye examination regularly while taking this medication.
Side Effects :
Inflammation of throat and nasal passages, back pain and upper respiratory tract infection.
Nausea or vomiting, stomach pain, loss of appetite, fractures, low blood sugar, vision changes.
Other Precautions :
Avoid excess dosage.
Storage Conditions :
Store it at room temperature (20°C to 25°C).