Why it is prescribed :
This combination medication contains dipeptidyl-peptidase-4 (DPP-4) inhibitor and a biguanide, prescribed for type 2 diabetes mellitus along with diet and exercise.
When it is not to be taken (Contraindications):
Contraindicated in patients with severe kidney impairment, metabolic acidosis, including diabetic ketoacidosis, and hypersensitivity.
Dosage & When it is to be taken (Indications):
(125mg/500mg)- Dose is based on patient’s condition.
How it should be taken :
It comes as a tablet to take by mouth, with food two times per day.
Warnings and Precautions :
Caution should be exercised in patients with history of pancreatitis, kidney or liver problems, heart problems, alcoholism, any allergy, who are taking other medications, during pregnancy and breastfeeding.
It may cause serious side effects such as lactic acidosis and pancreatitis; if it is so stop taking this medication immediately and contact your healthcare provider.
Side Effects :
Lactic Acidosis and pancreatitis.
Upper respiratory tract infection, nasopharyngitis, diarrhea, hypertension, headache, back pain and urinary tract infection.
Other Precautions :
Avoid excess dosage.
Storage Conditions :
Store it at room temperature between (20°C to 25°C).