Trade Names/Brand Names :
Why it is prescribed :
This combination medication contains renin inhibitor and angiotensin II receptor blocker, prescribed for high blood pressure either alone or with other medications.
When it is not to be taken (Contraindications):
Contraindicated in pregnant women and in patients with known hypersensitivity.
Category D :
There is an evidence of fetal risk based on adverse reaction data, but potential benefits may allow the drug to be used in pregnant women despite risks.
Dosage & When it is to be taken (Indications):
The recommended dose is 150/160 mg or 300/320 mg once daily.
Maximum: 300/320 mg.
How it should be taken :
It comes as a tablet to take by mouth, with or without food.
Warnings and Precautions :
• Caution should be exercised in patients with history of blood vessel problems, blood flow problems, heart, liver, kidney disease, gout, gallbladder problems, sugar, stroke, recent heart attack, dehydration, low blood volume, severe allergic reactions, during pregnancy and breastfeeding.
It may cause drowsiness, dizziness, or blurred vision, do not drive a car or operate machinery and get up slowly from bed while taking this medication.
It may cause a serious side effect called angioedema with the following symptoms: swelling in the face, ear, neck etc; breathing trouble, fever, difficulty in swallowing, and shock. If it is so consult with your doctor.
Monitor blood pressure, blood electrolyte levels, heart, kidney, and liver functions regularly while taking this medication.
It should not be used in children.
Side Effects :
• Most Common
Shock and low blood pressure.
Bladder pain, bloody or cloudy urine, painful urination and urine urgency.
Cough, difficulty in breathing, runny nose, nasal congestion and sneezing.
Body pain, chills, fever, shivering, general discomfort, headache, and tiredness.
Diarrhea, loss of appetite, nausea and vomiting.
Ear congestion and loss of voice.
Joint pain, lower back pain and muscle pain.
Other Precautions :
Avoid excess dosage.
Storage Conditions :
Store it at room temperature (25°C).