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Aliskiren and hydrochlorothiazide

Latest prescription information about Aliskiren and hydrochlorothiazide. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Aliskiren and hydrochlorothiazide
Pronunciation : a-lis-KYE-ren/HYE-droe-KLOR-oh-THYE-a-zide
Trade Name(s): 
International- Tekturna HCT.
Why it is prescribed (Indications) : 
This medication is a direct renin inhibitor and thiazide diuretic combination, prescribed for high blood pressure.

When it is not to be taken (Contraindications): 


Contraindicated in patients with anuria (absence of urination), severe kidney problems, and hypersensitivity.

Pregnancy Category :

A B C D X
Category D : There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


When it is to be taken : 
Adult- Tablet- The recommended dose is 150/12.5 mg once daily, 150/25 mg or 300/12.5 mg, and 300/25 mg.
How it should be taken : 
It comes as a tablet to take by mouth, with or without food.
Special Instruction : 
* Caution should be exercised in patients with history of gout, lupus, sugar, asthma, heart, kidney, liver problems, kidney stones, thyroid problems, high blood cholesterol, receiving dialysis treatment, dehydration, who are in low-salt diet, blood electrolyte problems, severe allergy, who are taking other medications, during pregnancy and breastfeeding.
* It may cause dizziness, lightheadedness, or fainting, do not drive a car or operate machinery and get up slowly from bed while taking this medication.
* Avoid alcohol consumption.
* Patient may develop with serious side effect called angioedema with the following symptoms: swelling the hands, face, neck, etc; breathing trouble, and shock. If it is so consult with your doctor.
* Avoid exposure to sunlight; otherwise it may cause sunburn.
* It may affect sugar level; monitor blood sugar level regularly while taking this medication.
* Monitor blood pressure, blood electrolyte levels, and kidney function regularly while taking this medication.
Side Effects : 
Body As A Whole - Weakness.
Gastrointestinal - Inflammation of pancreas, jaundice, cramping and gastric irritation.
Blood - Anemia, decrease in white blood cells and platelets.
Hypersensitivity - Bruising, sensitivity to light, hives, tissue death, fever, respiratory distress, lung swelling/inflammation and shock.
Metabolic - Increased level sugar.
Musculoskeletal - Muscle spasm.
Central Nervous System - Restlessness.
Genitourinary - Kidney failure, kidney impairment and kidney inflammation.
Skin - Skin inflammation and skin death.
Eye and ENT - Blurred vision.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it at room temperature (25°C).

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