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Aliskiren, Amlodipine and Hydrochlorothiazide

Latest prescription information about Aliskiren, Amlodipine and Hydrochlorothiazide. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Aliskiren, Amlodipine and Hydrochlorothiazide
Pronunciation : AL is KYE ren, am LOE de peen, HYE droe klor oh THYE a zide
Trade Name(s): 
International- Amturnide.
Why it is prescribed (Indications) : This combination medication contains an anti-hypertensive agent, a calcium channel blocker, and a thiazide diuretic, prescribed for high blood pressure (hypertension).

When it is not to be taken (Contraindications): 

Hypersensitivity.

Pregnancy Category :

A B C D X
Category D : There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


When it is to be taken : Adult- PO- The maximum recommended dose is 300/10/25 mg.
How it should be taken : It comes as a tablet to take by mouth, with or without food.
Special Instruction : 
* Caution should be exercised in patients with history of kidney or liver disease, increased eye pressure, lupus, asthma, congestive heart failure, angioedema, chest pain, seizures, coronary artery disease, electrolyte imbalance, urinary obstruction, any allergy, who are taking other medications, during pregnancy and breastfeeding.
* Avoid alcohol consumption.
* It may cause drowsiness, dizziness, or blurred vision, do not drive a car or operate machinery while taking this medication.
* Patient may develop with an increased risk of angioedema with the following symptoms: swelling in the hands, face, lips, eyes, throat, or tongue; difficulty in swallowing or breathing. If it is so consult with your doctor.
* Avoid exposure to sunlight.
* Monitor blood pressure, kidney function, sugar level, and blood electrolyte levels regularly while taking this medication.
Side Effects : 
Most Common - Swelling in the extremities, dizziness, headache and throat inflammation.
Heart - Abnormal heart rhythm, slow heart rate, chest pain, peripheral ischemia, fainting, low blood pressure and inflammation of blood vessels.
Central Nervous System - Peripheral neuropathy, tingling, tremor, sexual dysfunction, sleeplessness, nervousness, depression, abnormal dreams, anxiety and depersonalization.
Gastrointestinal - Loss of appetite, constipation, indigestion, difficulty in swallowing, diarrhea, flatulence, pancreatitis, vomiting and gum inflammation.
General - Allergic reaction, weakness, back pain, hot flushes, uneasiness, pain, rigors, weight gain.
Musculoskeletal - Joint pain, muscle cramps and muscle pain.
Respiratory - Difficulty in breathing and nosebleed.
Skin - Redness, itching and rash.
Eye and ENT - Abnormal vision, eye inflammation, double vision, eye pain and ringing in the ear.
Genitourinary - Urination frequency and nighttime urination.
Metabolic - Increased blood sugar, thirst, sweating and dry mouth.
Blood - Decrease in the number of white blood cells and platelets, bruising.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it at room temperature (25°C). Protect from heat and moisture.

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