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Alglucosidase

Latest prescription information about Alglucosidase. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Alglucosidase
Pronunciation : AL-gloo-KOE-si-dase
Trade Name(s): 
International- Lumizyme and Myozyme.
Why it is prescribed (Indications) : 
This medication is a glycoprotein, prescribed for pompe disease.

When it is not to be taken (Contraindications): 


Hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


When it is to be taken : 
The recommended dosage is 20-mg/kg body weight administered every 2 weeks as an intravenous infusion.
How it should be taken : 
It comes as a solution for injection to be administered by a healthcare provider into the vein.
Special Instruction : 
* Caution should be exercised in patients with history of heart or lung problems, any allergy, who are taking other medications, children, during pregnancy and breastfeeding.
* Monitor liver function regularly while taking this medication.
Side Effects : 
Most common- Hives, diarrhea, vomiting, difficulty in breathing, itching, rash, throat and neck pain.
Blood and lymphatic- Swollen glands.
Eye and ENT- Hearing loss, ear discomfort or pain and blurred vision.
Gastrointestinal - Constipation, indigestion and vomiting.
General - Chest discomfort or pain, injection site reactions, uneasiness and swelling in the extremities.
Immune system- Anaphylaxis, infections and stomach inflammation.
Respiratory - Upper respiratory tract infection, procedural complications and procedural pain.
Metabolic - Decreased potassium level in blood.
Musculoskeletal - Muscle twitching, musculoskeletal pain and musculoskeletal stiffness or tightness.
Central Nervous system- Drowsiness and tremor.
Genitourinary - Kidney stones.
Respiratory - Shortness of breath during exercise and nosebleed.
Skin - Increased sweating.
Other Precautions : 
*Avoid excess dosage.
Storage Conditions : 
Store it in refrigerator (2° to 8°C), do not freeze it. Remove the required number of vials from the refrigerator and allow them to reach room temperature prior to reconstitution (approximately 30 minutes).

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