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Alfentanil Hydrochloride Injection

Latest prescription information about Alfentanil Hydrochloride Injection. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Alfentanil Hydrochloride Injection
Pronunciation : al-FEN-tuh-NILL HIGH-droe-KLOR-ide
Therapeutic Classification : Analgesics
ICD Code : Y45.8
Trade Name(s): 
International- Alfenta.
Why it is prescribed (Indications) : 
This medication is a strong analgesic, prescribed for relieving pain and induction of anesthesia in specific situations. It provides analgesic protection against hemodynamic responses to surgical stress with recovery times.
When it is not to be taken (Contraindications): 
Contraindicated in patients with known hypersensitivity

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : 
IV- The recommended dose range is 8 to 245mcg/kg.
How it should be taken : 
It comes as a solution for injection, to be administered by a healthcare provider into the vein.
Warnings and Precautions : 
* Caution should be exercised in patients with history of kidney, liver, heart, or thyroid disease, seizures, asthma, lung inflammation, during pregnancy and breastfeeding.
* It may cause blurred vision, dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.
* Avoid alcohol consumption.
Side Effects : 
Most Common - Respiratory depression and skeletal muscle rigidity.
Gastrointestinal - Nausea, vomiting.
Heart - Abnormal heart rhythm, slow heart rate, high blood pressure, low blood pressure, fast heart rate.
Musculoskeletal - Chest wall rigidity, skeletal muscle movements.
Respiratory - Postoperative respiratory depression.
Central Nervous System - Blurred vision, dizziness, sleepiness/postoperative sedation.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store at 20° to 25°C.

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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