Ado-trastuzumab Emtansine - Drug Information

Email Print This Page Comment bookmark
Font : A-A+

Generic Name : Ado-trastuzumab Emtansine

Latest prescription information about Ado-trastuzumab Emtansine. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.

Trade Names/Brand Names : 

International- Kadcyla.

Why it is prescribed : 

This medication is a HER2-targeted antibody and microtubule inhibitor, prescribed as a single medicine for the treatment in patients with HER2-positive metastatic breast cancer who have previously received trastuzumab and a taxane separately or in combination. Patients should have either received prior therapy for metastatic disease, or developed disease recurrence during or within six months of completing adjuvant therapy. .  

When it is not to be taken (Contraindications): 

None.

Dosage & When it is to be taken (Indications): 

IV- The recommended dose is 3.6 mg/kg every 3 weeks (21-day cycle).

How it should be taken : 

It comes as powder for injection (diluted with fluid), to be administered by a healthcare provider into the vein.

Warnings and Precautions : 

Caution should be exercised in patients with history of liver or heart problem, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.
Ado-trastuzumab emtansine should not be administered at doses greater than 3.6 mg/kg.
Should not substitute for or with trastuzumab.
Monitor platelet counts prior to each dose of this drug administration.
Perform HER2 testing while taking this medication.
Discontinue this medication in patients diagnosed with interstitial lung disease or pneumonitis.

Side Effects : 

   Serious Effects : Lung problems, injection site reactions, nerve damage, heart damage, embryo-fetal toxicity.
   Most Common : Fatigue, nausea, muscle and bone pain, decrease in platelet counts, headache, increased level of liver enzymes and constipation.
   Miscellaneous : Tiredness, liver problems, nerve problems.


Other Precautions : 

Avoid excess dosage.

Storage Conditions : 

Store vials in a refrigerator at 2C to 8C.


Post a Comment

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
Notify me when reply is posted
I agree to the terms and conditions
Buy Medication (Drug) at Concessional Price from India

Drugs A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Drugs Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Find a Doctor
Advertisement

Stay Connected

  • Available on the Android Market
  • Available on the App Store

Facebook