Why it is prescribed :
This combination medication contains retinoid and keratolytic agent, prescribed for acne in patients 9 years of age and older.
Adapalene works by affecting the growth of cells and decreasing swelling and inflammation. Benzoyl peroxide works by reducing the amount of acne-causing bacteria and by causing the skin to dry and peel off.
When it is not to be taken (Contraindications):
Category C :
Animal studies have shown adverse effects on the fetus and there are no appropriate studies in pregnant women, but potential benefits may allow the use of the drug in pregnant women despite the potential for risks.
Dosage & When it is to be taken (Indications):
Apply a thin film to the affected areas of the face and/or trunk once daily after washing.
How it should be taken :
It comes as a gel to apply topically as directed by your physician.
Warnings and Precautions :
Caution should be exercised in patients with history of eczema, damaged skin, or a sunburn at the affected area, any allergy, who are taking other medications especially while using other sulfur, resorcinol, or salicylic acid containing medications to treat acne, during pregnancy and breastfeeding.
Caution should be taken if the patient has a history of skin sensitivity to the sun, or spends a lot of time outdoors.
For external use only; avoid contact with eyes, mouth, or nose. Do not apply to the inner lip area, inside the nose/mouth, or on mucus membranes
Side Effects :
Dry skin, feeling of warmth, contact dermatitis, application site burning, irritation, scaling, dryness, itching, and blister.
Other Precautions :
Avoid excess dosage.
Do not use moisturizers that contain alpha hydroxy or glycolic acids.
Storage Conditions :
Store at 25°C, excursions permitted to 15° – 30° (59° – 86°F). Protect from light and heat.