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Acrivastine and Pseudoephedrine

Latest prescription information about Acrivastine and Pseudoephedrine. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Acrivastine and Pseudoephedrine
Pronunciation : AK-ri-vas-teen-soo-doe-e-FED-rin
Therapeutic Classification : Antihistamines And Decongestants
ICD Code : Y55.5
Trade Name(s): 
International- Semprex D.
Why it is prescribed (Indications) : 
This medication is an antihistamine and decongestant combination, prescribed for seasonal allergic rhinitis such as sneezing, rhinorrhea, pruritus, lacrimation, and nasal congestion.  It narrows blood vessels and shrinkage of the nasal mucous membranes by blocking histamine at H1 receptor sites.
When it is not to be taken (Contraindications): 
Contraindicated in patients with severe high blood pressure, hypersensitivity, who are taking or have taken monoamine oxidase (MAO) inhibitors within 14 days.

Pregnancy Category :

A B C D X
Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Dosage & When it is to be taken : 
PO- Adults- The recommended dose is one capsule (8mg/60mg), every 4 to 6 hours four times a day.
How it should be taken : 
It comes as a capsule to take by mouth, with or without food.
Warnings and Precautions : 
* Caution should be exercised in patients with history of high blood pressure, heart disease, diabetes, overactive thyroid, increased eye pressure, kidney disease, stomach or bowel obstruction, peptic ulcer, urinary tract problems, prostate disease, difficulty in urinating, who are taking other medications, any allergy, elderly, children, during pregnancy and breastfeeding.
* It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.
* Avoid alcohol consumption.
* It may affect blood sugar levels; monitor blood sugar regularly.
Side Effects : 
Central Nervous System - Drowsiness, headache, dizziness, nervousness, sleeplessness.
Gastrointestinal - Nausea, dry mouth, weakness, indigestion, inflammation of pharynx.
Miscellaneous - Increased cough, painful menstruation.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store at 15° to 25° C in a dry place and protected from light.


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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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