Acrivastine and Pseudoephedrine - Drug Information

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Generic Name : Acrivastine and Pseudoephedrine

Pronunciation : AK-ri-vas-teen-soo-doe-e-FED-rin

Latest prescription information about Acrivastine and Pseudoephedrine. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y55.5 | Therapeutic Classification : Antihistamines And Decongestants

Trade Names/Brand Names : 

International- Semprex D, Benadryl plus.

Why it is prescribed : 

This medication contains a non-sedating antihistamine (acrivastine), and a nasal decongestant(pseudoephedrine) which is prescribed to temporarily relieve seasonal allergic rhinitis such as sneezing, rhinorrhea, pruritus, lacrimation, nasal congestion. It is also used for itchy or watery eyes, hives, skin rash, itching, and other symptoms of allergies and the common cold. It narrows blood vessels and shrinkage of the nasal mucous membranes by blocking histamine at H1 receptor sites.  It narrows blood vessels and shrinkage of the nasal mucous membranes by blocking histamine at H1 receptor sites.

When it is not to be taken (Contraindications): 

Contraindicated in patients with severe high blood pressure, hypersensitivity, who are taking or have taken monoamine oxidase (MAO) inhibitors within 14 days.

Pregnancy Category :


A B C D X

Category B :

Animal studies have failed to demonstrate a risk to the fetus and appropriate studies on pregnant women are lacking.

Dosage & When it is to be taken (Indications): 

PO- Adults- The recommended dose is one capsule (8mg/60mg), every 4 to 6 hours four times a day.

How it should be taken : 

It comes as a capsule to take by mouth, with or without food. Take this with food if stomach upset occurs.

Warnings and Precautions : 

Caution should be exercised in patients with history of high blood pressure, heart disease, diabetes, overactive thyroid, increased eye pressure, kidney disease, stomach or bowel obstruction, peptic ulcer, urinary tract problems, prostate disease, difficulty in urinating, who are taking other medications, any allergy, elderly, children, during pregnancy and breastfeeding.
Should not be used in children under 12 years of age and people who have taken a monoamine-oxidase inhibitor antidepressant (MAOI) in the last 14 days.
It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.
Avoid alcohol consumption.
It may affect blood sugar levels; monitor blood sugar regularly.

Side Effects : 

   Central Nervous System : Drowsiness, headache, dizziness, nervousness, sleeplessness.
   Gastrointestinal : Nausea, dry mouth/nose/throat, weakness, indigestion, inflammation of pharynx.
  Heart - Increased heart rate, increased blood pressure.
   Miscellaneous : Increased cough, difficulty in passing urine and painful menstruation.

Other Precautions : 

Avoid excess dosage.
If you miss a dose of acrivastine/pseudoephedrine, skip the missed dose. Do not take 2 doses at once.

Storage Conditions : 

Store at 15 to 25 C in a dry place and protected from light.


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