Acitretin - Drug Information

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General Information on Acitretin

Generic Name : Acitretin

Pronunciation : A-si-TRE-tin

Latest prescription information about Acitretin. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
Therapeutic Classification : Antipsoriatics

Trade Names/Brand Names of Acitretin

India : 

International : 

Neotigason, Soriatane, Soriatane CK

Why is Acitretin Prescribed? (Indications)

This medication is a synthetic retinoid, prescribed for severe psoriasis (abnormal growth of skin cells that causes red, thickened, or scaly skin)It regulates the growth of epidermal cells. 

When should Acitretin not to be taken? (Contraindications)

Contraindicated in patients with liver, kidney impairment, during pregnancy (before the start, during and at least 2-3 yr after cessation of therapy), lactation, increased level of lipids in blood.

Pregnancy Category

A B C D X

Category X :

Animal and/or human studies have demonstrated fetal injury and potential risks outweigh the benefits of the drug in pregnancy. These drugs are found to be harmful when taken during pregnancy, and should not be used.

What is the dosage of Acitretin?

Adult: PO- The recommended dose is 25 to 50 mg per day, given as a single dose with the main meal.

How should Acitretin be taken?

It comes as a capsule to take by mouth. It is usually taken once a day with the main meal.

What are the warnings and precautions for Acitretin?

It may cause drowsiness or vision changes. Do not drive a car or operate machinery while taking this medication.
Acitretin is noted for the possibility of severe birth defects and should not be used by pregnant women or women planning to get pregnant within 3 years following the use of this medication.
Sexually active women of childbearing age who use Acitretin should also use at least 2 forms of birth control concurrently.
Avoid blood donation during therapy or at least 1-3 years after stopping therapy.
It may make your skin sensitive to light, so avoid sunlight.
Remove contact lenses while using this medication otherwise it will increase irritation.
Monitor liver function, plasma lipid and glucose levels (especially in diabetic patients) regularly.

What are the side effects of Acitretin?

Hypervitaminosis A syndrome (Excess intake of Vitamin A).
  Heart: Heart attack, clots in blood vessels and stroke.
  Central Nervous System: Headache, shakiness, sleeplessness, aggressive feelings and/or suicidal thoughts and depression.
  Gastrointestinal: Dry mouth, increased thirst, taste changes, nausea, vomiting, inflammation of the pancreas and lower stomach pain.
  Skin: Rash, sweating, itching, scaling, dryness, thinning, dry or chapped lips, damage of skin, abnormal skin odor, hair loss and nail damage.
  Genitourinary: Vulvo-vaginal infection due to fungal infection.
  Hypersensitivity: Allergic reaction includes: rash, itching/swelling (especially of the face/tongue/throat), dizziness and trouble in breathing.
  Miscellaneous: Fever, chills, dark urine and peeling of skin.
  Potentially Fatal: Sunburn, jaundice and liver toxicity.

What are the other precautions for Acitretin?

Avoid alcohol consumption while taking this medication.
Do not double the dose to catch up missed dosage.

What are the storage conditions of Acitretin?

Store between 15 and 25C (59 and 77F) in an airtight container. Protect from light. Avoid exposure to high temperatures and humidity after the bottle is opened. Keep away from children.

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Please note for the minimum order for Exports is of US$ 200. All orders will be subject to courier charges and supplies are normally dispatched through internationally accredited courier services.

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