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Acetohexamide

Latest prescription information about Acetohexamide. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Acetohexamide
Pronunciation : a SEET oh HEX a mide
Therapeutic Classification : Antidiabetics
ICD Code : Y42.3
Trade Name(s): 
International- Dymelor.
Why it is prescribed (Indications) : 
This medication is a first-generation sulfonylurea agent, prescribed for type 2 (non-insulin dependent) diabetes. It increases insulin secretion by stimulating pancreas.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : 
PO- The recommended dose is 250-1500 mg two times per day; Maximum- 1500 mg/day.
How it should be taken : 
It comes as a tablet to take by mouth, with food.
Warnings and Precautions : 
* Caution should be exercised in patients with history of kidney or liver disease, thyroid disorder, heart disease, any allergy, who are taking other medications, during pregnancy and breastfeeding.
* Avoid alcohol consumption.
* Patient may experience low blood sugar with the following symptoms: extreme weakness, blurred vision, sweating, trouble speaking, tremor, stomach pain, confusion, seizure, or coma. If it is so consult with your doctor.
* It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.
Side Effects : 
Most Common - Swelling, rapid weight gain, increased urination, pale or yellowed skin, dark colored urine, fever, confusion, weakness.
Gastrointestinal - Nausea, stomach pain, constipation, diarrhea, loss of appetite, low fever, clay-colored stools, jaundice.
Central Nervous System - Dizziness, drowsiness.
Miscellaneous - Fever, sore throat and headache.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it at room temperature.

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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