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Acetaminophen and Oxycodone
Latest prescription information about Acetaminophen and Oxycodone. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Acetaminophen and Oxycodone
Pronunciation : (a set a mee' noe fen) (ox i koe' done)
Therapeutic Classification : Analgesics
ICD Code : Y45.8
Trade Name(s): International- Percocet, Roxicet, Tylox, Oxycet, Roxilox. Why it is prescribed (Indications) : This combination medication is a narcotic analgesic, prescribed for moderate to severe pain. Acetaminophen increases the effects of Oxycodone, which is an opioid pain medication. When it is not to be taken (Contraindications): Contraindicated in patients with significant respiratory depression, intestinal obstruction and hypersensitivity.
Dosage & When it is to be taken : The usual adult dosage is one tablet every 6 hours as needed for pain. The total daily dose of acetaminophen should not exceed 4 grams. How it should be taken : It comes as a tablet and capsule to take by mouth, with or without food. Warnings and Precautions : * Caution should be exercised in patients with history of liver or kidney diseases, heart problems, lung disease, seizure disorders, serious head injury or brain diseases, spinal problems, underactive thyroid, adrenal gland problems, breathing problems, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding. * It may cause dizziness, lightheadedness, blurred vision or drowsiness, do not drive a car or operate machinery and get up slowly from bed while taking this medication. * Avoid alcohol consumption. * It may lead to constipation; take proper diet and drink adequate water. Side Effects : Serious - Respiratory depression, difficulty in breathing, respiratory arrest, circulatory depression, low blood pressure and shock. Body as a Whole - Severe allergic reactions, uneasiness, weakness, fatigue, chest pain, fever, chills, thirst, headache and increased sweating. Heart - High/low blood pressure, fast/slow heart rate and palpitations. Central Nervous System - Lack of consciousness, tremor, tingling, drowsiness, epilepsy, anxiety, mental impairment, agitation, swelling of the brain, confusion, dizziness, sleeplessness, nervousness, hallucinations, depression, suicidal thoughts and drug abuse. Gastrointestinal - Indigestion, taste disturbances, abdominal pain, enlarged abdomen, increased sweating, diarrhea, dry mouth, flatulence, gastrointestinal disorders, nausea, vomiting, inflammation of pancreas, intestinal obstruction. Liver - Liver failure and jaundice. Eye and ENT - Hearing loss, ringing in the ear, visual disturbances and redness of eye. Blood - Decreased platelet count. Metabolic - Decreased/increased sugar level in blood, acidity, alkalosis and dehydration. Musculoskeletal - Muscle pain and weakness. Respiratory - Asthma, lung swelling and fast breathing. Skin and Appendages - Redness, rash, flushing and hives. Genitourinary - Liver inflammation, papillary necrosis, protein in urine, kidney insufficiency, kidney failure and urinary retention. * If condition worsens consult with your doctor. * Avoid excess dosage. Storage Conditions : Store it at room temperature (20° to 25°C) and in an airtight container. Keep away from children. |
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Reference
- Food and Drug Administration (FDA)
- National Institutes of Health (NIH)
- PubMed
- CIMS
- Indian Pharma Reference Guide 2012
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