Acetaminophen, Butalbital and Caffeine - Drug Information

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General Information on Acetaminophen, Butalbital and Caffeine

Generic Name : Acetaminophen, Butalbital and Caffeine

Pronunciation : (a set a mee' noe fen) (byoo tal' bi tal) (kaf' een)

Latest prescription information about Acetaminophen, Butalbital and Caffeine. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y45.8 | Therapeutic Classification : Analgesics

Trade Names/Brand Names of Acetaminophen, Butalbital and Caffeine

India- Dolopar.
International- DDolgic Plus, Esgic-Plus, Esgic, Fioricet, Anolor 300, Cephadyn, Esgic-Plus,Orbivan CF.

Why is Acetaminophen, Butalbital and Caffeine Prescribed? (Indications)

This combination medication contains analgesic, antipyretic and depressant agent, prescribed for tension headache, pain and anxiety. It works by relaxing muscle contractions. Acetaminophen is a pain reliever and fever reducer, butalbital relaxes muscle contractions involved in a tension headache and caffeine is a central nervous system stimulant which relaxes muscle contractions in blood vessels to improve blood flow.  It works by relaxing muscle contractions.

When should Acetaminophen, Butalbital and Caffeine not to be taken? (Contraindications)


Pregnancy Category


Category C :

Animal studies have shown adverse effects on the fetus and there are no appropriate studies in pregnant women, but potential benefits may allow the use of the drug in pregnant women despite the potential for risks.

What is the dosage of Acetaminophen, Butalbital and Caffeine?

1 or 2 tablets every 4 hours as needed. Total daily dosage should not exceed 6 tablets. The dose is based on the medical condition and response to therapy.

How should Acetaminophen, Butalbital and Caffeine be taken?

It comes as a tablet, capsule and solution to take by mouth, with or without food.

What are the warnings and precautions for Acetaminophen, Butalbital and Caffeine?

Caution should be exercised in patients with history of liver problems, a certain enzyme disorder (porphyria), severe kidney problems, severe heart diseases, lung or respiratory tract diseases, sleeping disorders, alcohol dependence, anxiety, depression, suicidal thoughts, who are taking other medications, elderly, children, during pregnancy and breastfeeding.
It may cause drowsiness, do not drive a car or operate machinery, while taking this medication.
Avoid alcohol consumption; otherwise it may cause liver damage.
It may decrease the effectiveness of birth control pills; take additional measures for birth control.
Do not use this medication if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days.

What are the side effects of Acetaminophen, Butalbital and Caffeine?

   Most Common : Drowsiness, lightheadedness, tremor, dizziness, sedation, shortness of breath, nausea, vomiting, and abdominal pain.
   Central Nervous System : Headache, shaky feeling, tingling, agitation, fainting, fatigue, heavy eyelids, high energy, hot spells, numbness, sluggishness, intoxicated feeling and seizures.
   Gastrointestinal : Difficulty in swallowing, loss of appetite, flatulence, constipation and dry mouth.
   Heart : Fast, pounding, or uneven heartbeat, heartburn.
   Musculoskeletal : Leg pain and muscle weakness.
   Genitourinary : Increased urination, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
   Miscellaneous : Itching, earache, nasal congestion, ringing in the ear and allergic reactions.

What are the other precautions for Acetaminophen, Butalbital and Caffeine?

Avoid excess dosage.
Extended and repeated use of this product is not recommended because of the potential for physical dependence.

What are the storage conditions of Acetaminophen, Butalbital and Caffeine?

Store it at room temperature (20 to 25C) and in an airtight container. Keep away from children.

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Pls advise if anyone knows the mfg of this product

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