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Acebutolol

Latest prescription information about Acebutolol. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Acebutolol
Pronunciation : A se BUE toe lol
Therapeutic Classification : Antidiabetics
ICD Code : Y42.3
Trade Name(s): 
International- Sectral, Prent.
Why it is prescribed (Indications) : 
This medication is a beta-blocker, prescribed for high blood pressure, and arrhythmias (abnormal rhythms of the heart). The medication relaxes blood vessels and improves blood flow. 
When it is not to be taken (Contraindications): 
Contraindicated in patients with severe heart diseases.

Pregnancy Category :

A B C D X
Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Dosage & When it is to be taken : 
PO- The recommended initial dose is 200-400mg, twice daily. The maximum allowed dose is 1200mg.
How it should be taken : 
It comes as a capsule to take by moth, with or without food.
Warnings and Precautions : 
* Caution should be exercised in patients with history of heart, kidney or liver disease, who are taking other medications, asthma or other lung diseases, diseases of the blood vessels, severe allergies, diabetes, thyroid disorder, during pregnancy and breastfeeding.
* It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.
* Avoid alcohol consumption while taking this drug.
Side Effects : 
Heart- Chest pain, swelling in chest cavity, uneven heartbeats, low blood pressure and heart failure.
Central Nervous System- Depression, fainting, dizziness, fatigue, headache, sleeplessness and abnormal dreams.
Skin- Rash and itching.
Gastrointestinal - Constipation, diarrhea, indigestion, flatulence, nausea, vomiting and abdominal pain.
Genitourinary - Increased urination, painful urination and excessive urinating at night.
Musculoskeletal - Joint/muscle pain.
Respiratory- Cough, difficulty in breathing and inflammation of nose.
Liver- Liver abnormalities and increase in liver enzymes.
Special Senses - Abnormal vision, dry eye and eye pain.
Other Precautions : 
* Avoid abrupt withdrawal.
Storage Conditions : 
Store it at controlled room temperature (20° to 25°C). Keep away from children.

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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