Abciximab - Drug Information

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Generic Name : Abciximab

Pronunciation : ab-SIKS-ih-mab

Latest prescription information about Abciximab. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y44.2 | Therapeutic Classification : Anticoagulants / Antithrombotics

Trade Name(s): 

India : 

International : 

Reopro

Why it is prescribed : 

This medication prevent blood clotting by interfering with clumping of platelets.  

When it is not to be taken (Contraindications): 

Active bleeding
Recent bleeding due to surgery, bleeding from the digestive tract or from other sites, stroke due to a bleed
Increased risk for bleeding due to bleeding/clotting disorders, very high blood pressure, brain tumor, etc.
Allergic reaction

Pregnancy Category :

A B C D X

Category C :

Animal studies have shown adverse effects on the fetus and there are no appropriate studies in pregnant women, but potential benefits may allow the use of the drug in pregnant women despite the potential for risks.

Dosage & When it is to be taken (Indications): 

Before procedures on the heart like angioplasty. It is given in a dose of 0.25mg/kg into the vein 10-60 minutes before the procedure, followed by an infusion of 0.125 g/kg/min up to a maximum of 10 g/min for 12 hours .
Treatment of heart attack, stroke due to a blood clot

How it should be taken : 

Injected into the vein by a healthcare provider.

Warnings and Precautions : 


Platelet counts, bleeding and clotting times should be monitored before and during treatment
May cause excess bleeding when administered with other drug with bleeding as side effects. e.g. aspirin, warfarin, t-PA (tissue plasminogen activator) which is used to break clots

Storage Conditions : 

Store at 2 to 8C. Discard any unused portion left in the vial.


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