Why it is prescribed :
This medication prevent blood clotting by interfering with clumping of platelets.
When it is not to be taken (Contraindications):
Recent bleeding due to surgery, bleeding from the digestive tract or from other sites, stroke due to a bleed
Increased risk for bleeding due to bleeding/clotting disorders, very high blood pressure, brain tumor, etc.
Category C :
Animal studies have shown adverse effects on the fetus and there are no appropriate studies in pregnant women, but potential benefits may allow the use of the drug in pregnant women despite the potential for risks.
Dosage & When it is to be taken (Indications):
Before procedures on the heart like angioplasty. It is given in a dose of 0.25mg/kg into the vein 10-60 minutes before the procedure, followed by an infusion of 0.125 µg/kg/min up to a maximum of 10 µg/min for 12 hours .
Treatment of heart attack, stroke due to a blood clot
How it should be taken :
Injected into the vein by a healthcare provider.
Warnings and Precautions :
Platelet counts, bleeding and clotting times should be monitored before and during treatment
May cause excess bleeding when administered with other drug with bleeding as side effects. e.g. aspirin, warfarin, t-PA (tissue plasminogen activator) which is used to break clots
Storage Conditions :
Store at 2 to 8°C. Discard any unused portion left in the vial.