Abatacept - Drug Information

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Last Updated : August 2013

General Information on Abatacept

Generic Name : Abatacept

Pronunciation : a ba ta' sept

Latest prescription information about Abatacept. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y45.4 | Therapeutic Classification : Antirheumatics

Trade Names/Brand Names of Abatacept

International- Orencia.

Why is Abatacept Prescribed? (Indications)

This medication is a synthetic protein, prescribed for adult with moderate to severe rheumatoid arthritis including patients who have not responded to DMARDs (disease-modifying anti-rheumatic drugs), and juvenile idiopathic arthritis. It blocks the activity of T-cells, which causes swelling and joint damage in people with arthritis condition.  

When should Abatacept not to be taken? (Contraindications)

Hypersensitivity.

Pregnancy Category

A B C D X

Category C :

Animal studies have shown adverse effects on the fetus and there are no appropriate studies in pregnant women, but potential benefits may allow the use of the drug in pregnant women despite the potential for risks.

What is the dosage of Abatacept?

Dose is based on body weight and condition of the patient. Weight < 60 kg should receive 500 mg dose, weight 60-100 kg a 750 mg dose and weight >100 kg a 1000 mg dose.
Juvenile Idiopathic Arthritis- Pediatric patients weighing less than 75 kg: receive 10 mg/kg.

How should Abatacept be taken?

It is administered as an injection into the vein (intravenously), or as a solution for subcutaneous (under the skin) injection by a healthcare provider every 2 weeks for the first 3 doses and then every 4 weeks.

What are the warnings and precautions for Abatacept?

Patient may develop with serious infections and tumor. Caution should be exercised in patients with history of lung, nerve diseases (e.g. multiple sclerosis), cancer, Human Immunodeficiency Virus (HIV), tuberculosis (TB), severe combined immunodeficiency syndrome (SCID), cut or open sore, diabetes (especially if you are checking your blood sugar level at home), during pregnancy and breastfeeding.
Avoid vaccination while taking this medication.

What are the side effects of Abatacept?

  Serious: Infection and cancer.
  Central Nervous System : Headache and dizziness.
  Respiratory : Upper respiratory tract infection and inflammation of nasopharynx.
  Gastrointestinal : Nausea, indigestion and severe abdominal pain.
  Skin : Rash, red or painful skin, hives.
  Miscellaneous: Cough, fever, tiredeness, flu-like symptoms, or warm, swelling of the eyes, face, lips, tongue, or throat, back pain, high blood pressure, indigestion, heartburn, night sweats, urinary tract infection, change in the amount of urine and pain in arms and legs.
  Side effects in children : Upper respiratory tract infection, inflammation of nasopharynx, headache, nausea, diarrhea, cough and abdominal pain.

What are the other precautions for Abatacept?

Avoid excess dosage.
It should not be used as a first-line drug for the treatment.

What are the storage conditions of Abatacept?

Normally handled and stored by healthcare providers in refrigerator. Do not freeze and keep it away from light.

Last Updated : August 2013

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Lucasdon 

I recently read that this drug worked on 5 FSGS patients in US. Is this drung available in India? How can my doctor get an access to this drug for my FSGS condition? Any help will be greatly appreciated

Buy Medication (Drug) at Concessional Price from India

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