Trade Names/Brand Names :
Note: This brand is not available in US market.
Why it is prescribed :
This medication is a gonadotropin releasing-hormone (GnRH) antagonist, prescribed for prostate cancer (to treat it partially). It reduces testosterone (hormone) level in your body, which involves in the growth of most prostate cancers.
When it is not to be taken (Contraindications):
Contraindicated in women, children and individuals with known hypersensitivity.
Category X :
Animal and/or human studies have demonstrated fetal injury and potential risks outweigh the benefits of the drug in pregnancy. These drugs are found to be harmful when taken during pregnancy, and should not be used.
Dosage & When it is to be taken (Indications):
IM- The recommended dose is 100 mg on day 1, 15, 29 (week 4) and every 4 weeks thereafter.
How it should be taken :
It comes as a solution for injection to be administered by a healthcare provider into the buttock.
Warnings and Precautions :
• Caution should be exercised in patients with history of heart disease, including long QT syndrome, abnormal heart rhythm, liver disease, who are taking other medications, any allergy, and during breastfeeding.
It may cause dizziness, do not drive a car or operate machinery while taking this medication.
Monitor testosterone blood levels, prostate specific antigen (PSA), or liver function tests level regularly while taking this medication.
Side Effects :
Hot flushes, pain, breast enlargement, breast pain/nipple tenderness, painful urination, urination frequency, nausea, urinary retention and urinary tract infection.
• Central Nervous System
Sleep disturbances, dizziness, syncope, headache, and fatigue.
- Hypotension, peripheral edema.
Allergic reactions, back pain, constipation, swelling in the extremities, temporary redness of face and neck, upper respiratory tract infection and diarrhea.
Other Precautions :
Avoid excess dosage.
Storage Conditions :
Store the medication as directed by your physician.
Last Updated : August 2013