http://www.medindia.net/healthnews/Women-and-Cancer-news.asp Medindia largest health website in india. en-us Copyright 2012. All Rights Reserved. Fri, 25 May 2012 07:38:40 GMT http://www.medindia.net/news/heat-shock-protein-inhibitor-and-hormonal-therapy-combo-tested-in-breast-cancer-clinical-trial-101624-1.htm Pushed to the edge of survival, the hyper-driven cells of a cancerous tumor tap into an ancient system that has helped organisms cope with internal stresses and environmental challenges since life began. Most importantly in this system, heat shock protein 90 (HSP90) has been shown to help malignant cells accommodate the genetic changes and profound disturbances in normal biology that occur in cancers. Researchers have theorized that inhibiting HSP90 just might render breast cancer cells less ...]]> http://www.medindia.net/news/heat-shock-protein-inhibitor-and-hormonal-therapy-combo-tested-in-breast-cancer-clinical-trial-101624-1.htm http://www.medindia.net/news/hdac-inhibitor-successfully-targets-and-destroys-triple-negative-breast-cancer-101578-1.htm A new study published in the journal Breast Cancer Research reveals that using histone de-acetylase (HDAC) inhibitor panobinostat can target and destroy triple negative breast cancer. Researchers from Tulane University Health Sciences Center have shown that panobinostat was able to destroy breast cancer cells and reduce tumor growth in mice. Approximately 15% of breast cancers are found at diagnosis to be triple negative. These aggressive tumours are missing both the estrogen receptor and ...]]> http://www.medindia.net/news/hdac-inhibitor-successfully-targets-and-destroys-triple-negative-breast-cancer-101578-1.htm http://www.medindia.net/news/no-disparities-in-imaging-before-breast-cancer-surgery-fox-chase-researchers-101556-1.htm According to new findings that will be presented by Fox Chase Cancer Center researchers at the 2012 Annual Meeting of the American Society of Clinical Oncology on Monday, June 4 , if racial and ethnic disparities in breast cancer exist, they are not due to differences in the use of imaging to assess the extent of tumors before surgery. "It's encouraging that we didn't see any differences between black and white women in the use of imaging before surgery," says lead study author Richard J. Bleicher, M....]]> http://www.medindia.net/news/no-disparities-in-imaging-before-breast-cancer-surgery-fox-chase-researchers-101556-1.htm http://www.medindia.net/news/comprehending-breast-cancer-101542-1.htm Researchers describe nine new genes that drive the development of breast cancer in a study published today in iNature/i. The tally of all genes associated with breast cancer development is taken to 40 thanks to this. The team examined all the genes in the genomes of 100 cases of breast cancer. The mutated cancer-causing genes were different in different cancer samples, indicating that breast cancer is genetically very diverse. Understanding the consequences of this diversity will be important ...]]> http://www.medindia.net/news/comprehending-breast-cancer-101542-1.htm http://www.medindia.net/news/potential-to-prevent-breast-cancer-recurrence-via-hybrid-vaccine-101504-1.htm New research indicates that a breast cancer vaccine has the ability to improve recurrence rates and is well tolerated in an adjuvant setting. This vaccine has already been shown to elicit a powerful immune response in women with varying levels of HER2 expression. These are the findings from a clinical trial led by researchers at The University of Texas MD Anderson Cancer Center. The findings, released today, will be presented on Monday, June 4 in an oral presentation at the 2012 Annual Meeting ...]]> http://www.medindia.net/news/potential-to-prevent-breast-cancer-recurrence-via-hybrid-vaccine-101504-1.htm http://www.medindia.net/news/celery-and-parsley-could-help-fight-breast-cancer-101428-1.htm A new study has revealed that Apigenin, a natural substance found in celery and parsley, holds promise as a non-toxic treatment against aggressive breast cancer. University of Missouri researchers found apigenin shrank a type of breast cancer tumor that is stimulated by progestin, a synthetic hormone given to women to ease symptoms related to menopause. "This is the first study to show that apigenin, which can be extracted from celery, parsley and many other natural sources, is effective ...]]> http://www.medindia.net/news/celery-and-parsley-could-help-fight-breast-cancer-101428-1.htm http://www.medindia.net/news/scientists-identify-genetic-predictor-of-breast-cancer-response-to-chemotherapy-101288-1.htm While, chemotherapy is a major first line defense against breast cancer, a patient's response is often variable and unpredictable. A study published in BioMed Central's open access journal iBMC Medical Genomics/i shows that 'gene expression signatures' for TOP2A and (and) #946;-tubulin can be used to predict the outcome of chemotherapy. The goal of personalized medicine in cancer treatment is to target therapy to the characteristics of the individual tumor. For example Herceptin treatment ...]]> http://www.medindia.net/news/scientists-identify-genetic-predictor-of-breast-cancer-response-to-chemotherapy-101288-1.htm http://www.medindia.net/news/hysterectomies-in-cervical-cancer-patients-can-be-avoided-by-3-d-image-guided-brachytherapy-101202-1.htm New research suggests that relapse of cervical cancer can be prevented by delivering radiotherapy directly to cancer of the cervix using 3-D imaging techniques. This method also avoids the need for hysterectomies. The research was presented at the World Congress of Brachytherapy [1 (and) 2] today (Thursday). Dr Renaud Mazeron said that a review of the use of 3-D image guided adaptive brachytherapy (IGABT) after a course of chemotherapy and radiotherapy given together (concomitant chemoradiation) ...]]> http://www.medindia.net/news/hysterectomies-in-cervical-cancer-patients-can-be-avoided-by-3-d-image-guided-brachytherapy-101202-1.htm http://www.medindia.net/news/mysterious-missing-of-breast-cancer-genes-101132-1.htm Researchers are eager to improve their understanding on why the mutated genes for breast and ovarian cancer are not carried forward more often from one generation of women to the following. That's despite a documented link between breast cancer genes and increased fertility in women. Dr Jack da Silva from the University's School of /aMolecular (and) Biomedical Science/a says that because women who carry breast cancer genes are more fertile, in theory they have a greater chance of passing these genes on to future generations....]]> http://www.medindia.net/news/mysterious-missing-of-breast-cancer-genes-101132-1.htm http://www.medindia.net/news/screening-for-breast-cancer-without-x-rays-in-promising-diagnostic-technique-101105-1.htm An important diagnostic tool in the fight against breast cancer is X-ray mammography, but it has certain drawbacks that limit its effectiveness. For example, it can give in false positive and negative results; it also exposes women to low doses of ionizing radiation, which - while accepted as safe - still carry some risk. In the first phase of clinical testing of a new imaging device, researchers from Netherlands' University of Twente and Medisch Spectrum Twente Hospital in Oldenzaal used photoacoustics ...]]> http://www.medindia.net/news/screening-for-breast-cancer-without-x-rays-in-promising-diagnostic-technique-101105-1.htm http://www.medindia.net/news/death-rate-or-disease-recurrence-not-reduced-by-post-mastectomy-radiation-for-early-stage-breast-cancer-patients-100971-1.htm Radiation therapy following mastectomy may not have a significant effect on disease recurrence or mortality rates in early-stage breast cancer patients with one to three cancerous lymph nodes. These are the findings of a new study by investigators at The Cancer Institute of New Jersey (CINJ). The results are part of a poster presentation being given today at the 13th Annual Meeting of the American Society of Breast Surgeons being held in Phoenix. CINJ is a Center of Excellence of the University ...]]> http://www.medindia.net/news/death-rate-or-disease-recurrence-not-reduced-by-post-mastectomy-radiation-for-early-stage-breast-cancer-patients-100971-1.htm http://www.medindia.net/news/multiple-varieties-of-breast-cancer-better-understood-with-latest-data-100969-1.htm Various biological differences between individual breast cancers were elucidated with latest discoveries presented at Europe's leading breast cancer translational research conference this year. Focused on the biological features that make tumors more or less sensitive to important therapies, the new studies will help doctors make crucial choices about the most appropriate treatment for millions of patients. "Despite major advances in the treatment of breast cancer many patients continue ...]]> http://www.medindia.net/news/multiple-varieties-of-breast-cancer-better-understood-with-latest-data-100969-1.htm http://www.medindia.net/news/breast-cancer-in-young-women-a-distinct-disease-research-100934-1.htm Breast cancer in young women is a biologically unique disease that requires customized management strategies, researchers report at the 4th IMPAKT Breast Cancer Conference, in Brussels, Belgium. The reported findings have potentially important implications for treatment, because breast cancer in young women is often aggressive and diagnosed at an advanced stage, meaning the prognosis for these patients is often poor. Dr. Hatem A. Azim Jr., a medical oncologist from Institut Jules Bordet ...]]> http://www.medindia.net/news/breast-cancer-in-young-women-a-distinct-disease-research-100934-1.htm http://www.medindia.net/news/breast-cancer-more-lethal-for-men-100927-1.htm While all the new breast cancer programs focus on women, a new study has found that it is far more deadly among males with the survival chances among men being worse than that of women. The study was presented at the American Society of Breast Surgeons annual meet in Phoenix with lead researcher Dr John Greif from Oakland, California, saying that men with breast cancer die two years early than women who have the disease. Dr Greif also said that the tumors in men are bigger than in women at the ...]]> http://www.medindia.net/news/breast-cancer-more-lethal-for-men-100927-1.htm http://www.medindia.net/news/risk-of-breast-cancer-lowered-but-risk-of-colon-cancer-increased-by-fetal-cells-in-women-100923-1.htm A possible causative link between the concentration of circulating Y-chromosome fetal cells and the risk of developing breast cancer and colon cancer in women who gave birth to children of either sex has been found by scientists. The findings show that the presence of fetal cells is a double-edged sword: Women with the lowest concentration of fetal cells were 70 percent less likely to have breast cancer, while women with the highest concentration of fetal cells had a four-fold increased risk ...]]> http://www.medindia.net/news/risk-of-breast-cancer-lowered-but-risk-of-colon-cancer-increased-by-fetal-cells-in-women-100923-1.htm http://www.medindia.net/news/automated-breast-volume-sonography-improves-breast-cancer-screening-100837-1.htm Breast cancer screening and diagnosis in Asian women have been improved using automated breast volume sonography (ABVS), shows study. In their study on 504 findings in 212 patients at the Bangkok Breast Center, researchers found that ABVS agreed with HHUS in detecting 15 suspicious lesions, uncovered 12 additional suspicious lesions, and excluded 3 suspicious lesions in these cases. A coordinating five-year retrospective study on 26,741 mammograms with ultrasound also revealed that ultrasound ...]]> http://www.medindia.net/news/automated-breast-volume-sonography-improves-breast-cancer-screening-100837-1.htm http://www.medindia.net/news/vitamin-d-race-differences-and-breast-cancer-100832-1.htm In a case-control study, Song Yao, PhD of Rosewell Park Cancer Institute in Buffalo said that two variants in a gene playing an important role in the metabolism of bvitamin D/b was associated with an increased threat of bestrogen-receptor (ER) negative breast cancer /bin African American women. Researchers state that same gene variant showed no effects in women of European ancestry. American women are expected to have more bER-negative breast cancer risk/b than European counterparts....]]> http://www.medindia.net/news/vitamin-d-race-differences-and-breast-cancer-100832-1.htm http://www.medindia.net/news/coming-soon-blood-test-to-detect-breast-cancer-100759-1.htm A blood test to identify women at high risk of breast cancer could be available in five years, say scientists. Scientists at Imperial College London have identified a 'genetic switch', carried by one in five women, which doubles their risk of developing breast cancer. Experts described the breakthrough discovery as "exciting" and said signs of the disease could be detected "many decades in advance". Dr James Flanagan, who led the new research, said the test could be available in five to ten years, the Telegraph reported....]]> http://www.medindia.net/news/coming-soon-blood-test-to-detect-breast-cancer-100759-1.htm http://www.medindia.net/news/study-says-risk-factors-may-inform-breast-cancer-screening-100743-1.htm A family history of breast cancer and dense breast tissue increase the risk of breast cancer for women in their 40s', say researchers. The articles in the May 1 iAnnals of Internal Medicine/i provide information on how certain risk factors affect breast cancer risk and shift the balance between harms and benefits. Screening harms include false-positive results that can lead to invasive follow-up procedures and overdiagnosis, which prompts unnecessary treatment. Screening has a less ...]]> http://www.medindia.net/news/study-says-risk-factors-may-inform-breast-cancer-screening-100743-1.htm http://www.medindia.net/news/breast-cancer-survivors-can-get-better-quality-of-life-letting-go-of-old-goals-100604-1.htm Breast cancer survivors who chose and were able to let go of former goals and set fresh ones explained an improved overall well-being, discovered researchers. Once the self-imposed pressure of now unrealistic goals was removed, individuals' quality of life improved, as did their level of physical activity. Carsten Wrosch of Concordia University's Department of Psychology and Centre for Research in Human Development and Catherine Sabiston of McGill's Department of Kinesiology and Physical ...]]> http://www.medindia.net/news/breast-cancer-survivors-can-get-better-quality-of-life-letting-go-of-old-goals-100604-1.htm http://www.medindia.net/news/alcohol-consumption-breast-cancer-linked-100471-1.htm In a recent research work an association between drinking alcohol and breast cancer has been identified. "Cells have different mechanisms to remove toxic substances, such as ethanol, the chemical name for alcohol, that represent a potential risk to them," explains MarA-a de Lourdes RodrA-guez-Fragoso, professor of pharmacology and toxicology at the Universidad Autonoma del Estado de Morelos in Mexico. "Unfortunately, sometimes these mechanisms produce other toxic substances, including ...]]> http://www.medindia.net/news/alcohol-consumption-breast-cancer-linked-100471-1.htm http://www.medindia.net/news/cellular-glue-suppress-breast-cancer-100466-1.htm Desmosomes are involved in suppressing breast cancer, reveals study. Desmosomes attach neighbouring cells together and it is these tiny collections of proteins, which are responsible for the mechanical strength of organs and tissues within the body. Desmosomes are also thought to be involved in helping to suppress cancer. Researchers from Stanford University, UC Berkeley, and UC Davis have discovered that the protein Perp is found associated with desmosomes in breast epithelial cells....]]> http://www.medindia.net/news/cellular-glue-suppress-breast-cancer-100466-1.htm http://www.medindia.net/news/breast-cancer-growth-linked-to-common-environmental-contaminant-100465-1.htm Breast cancer cells become aggressive when exposed to small concentrations of cadmium, say Dominican University of California researchers. The study by Maggie Louie, associate professor of biochemistry, shows exposure to cadmium for prolonged periods of time can cause the progression of breast cancer to become more aggressive. Her findings will be presented Monday, April 23, at the annual meeting of the American Society for Biochemistry and Molecular Biology, held in conjunction with the ...]]> http://www.medindia.net/news/breast-cancer-growth-linked-to-common-environmental-contaminant-100465-1.htm http://www.medindia.net/news/canadian-scientists-find-new-breast-cancer-genes-100330-1.htm In what could prove to be a major breakthrough in treating breast cancer, Canadian scientists have found new breast cancer genes that has made it necessary to reclassify the disease into different categories. Researchers at the BC Cancer Agency and University of British Columbia have reclassified the disease into 10 completely new categories based on the genetic fingerprint of a tumour. Many of these genes could offer much-needed insight into breast cancer biology, allowing doctors to predict ...]]> http://www.medindia.net/news/canadian-scientists-find-new-breast-cancer-genes-100330-1.htm http://www.medindia.net/news/mans-health-under-stake-by-stressing-over-wifes-breast-cancer-100216-1.htm Taking care of a wife with breast cancer can have a reckonable negative impact on men's health, even years after the cancer diagnosis and end of treatment, states recent research. Men who reported the highest levels of stress in relation to their wives' cancer were at the highest risk for physical symptoms and weaker immune responses, the study showed. The researchers sought to determine the health effects of a recurrence of breast cancer on patients' male caregivers, but found that how ...]]> http://www.medindia.net/news/mans-health-under-stake-by-stressing-over-wifes-breast-cancer-100216-1.htm http://www.medindia.net/news/customized-decision-guide-removes-doubt-about-breast-cancer-prevention-100176-1.htm Providing a customized decision guide about available preventive options for women with high risk of breast cancer could make them choose a particular method and feel comfortable about it. Researchers developed a web-based tool called the Guide to Decide, which included general information about breast cancer and personalized information about an individual woman's five-year risk of breast cancer. The guide walked women through two medical options to prevent breast cancer: tamoxifen and raloxifene....]]> http://www.medindia.net/news/customized-decision-guide-removes-doubt-about-breast-cancer-prevention-100176-1.htm http://www.medindia.net/news/new-breast-cancer-rehabilitation-model-100163-1.htm An innovative model that addresses a wide range of physical issues faced by women with breast cancer has been developed by researchers and is reported in the journal Cancer. A panel of experts proposes a prospective surveillance model (PSM) that could reduce the incidence and severity of breast cancer treatment-related physical impairments. The model was developed over the past year by a panel of internationally known experts, with the support of the American Cancer Society and input from national ...]]> http://www.medindia.net/news/new-breast-cancer-rehabilitation-model-100163-1.htm http://www.medindia.net/news/new-type-of-mutation-in-breast-cancer-100160-1.htm A new class of molecular mutation in various forms of breast cancer has been discovered by Mayo Clinic researchers. This finding that may shed new light on development and growth of different types of breast tumors. Called fusion transcripts, the mutated forms of RNA may also provide a way to identify tumor subtypes and offer new strategies to treat them, investigators say. Their study, published in the April 15 issue of iCancer Research/i, is the first to systematically search for ...]]> http://www.medindia.net/news/new-type-of-mutation-in-breast-cancer-100160-1.htm http://www.medindia.net/news/protein-valuable-in-forecasting-the-pulmonary-metastases-risk-in-breast-cancer-patients-identified-100144-1.htm Breast cancer cells that metastasize to the lung express a higher level of the protein peroxiredoxin 2 (PRDX2) demonstrate researchers from the Bellvitge Biomedical Research Institute (IDIBELL). The study suggests that the modulation of the levels of this protein could be a new therapeutic strategy to prevent lung metastases. The study results have been advanced in the online edition of the journal IOncogene/I. PRDX2 is an oxidation-reduction enzyme that protects cells against free radicals and hence from oxidative stress....]]> http://www.medindia.net/news/protein-valuable-in-forecasting-the-pulmonary-metastases-risk-in-breast-cancer-patients-identified-100144-1.htm http://www.medindia.net/news/biomarkers-linked-with-chemo-resistance-in-breast-cancer-found-100117-1.htm Researchers from the University of Hull, UK, have identified a family of biomarkers associated with resistance to chemotherapy in breast cancer. The researchers found a family of proteins to be twice as prevalent in clinical samples obtained from breast cancer patients who were resistant to chemotherapy than those who were successfully treated. Chemotherapy resistance is a major problem for some types of breast cancer and many patients undergo treatment that does not work, delaying other ...]]> http://www.medindia.net/news/biomarkers-linked-with-chemo-resistance-in-breast-cancer-found-100117-1.htm http://www.medindia.net/news/exercise-reduces-fatigue-and-depression-in-breast-cancer-patients-100088-1.htm Physical activity could help to ward off distressing side effects and improve psychological well-being in women who are undergoing treatment for breast cancer. According to the University of Miami (UM) study, women who are physically active during treatment have less depression and an enhanced quality of life and report less debilitating fatigue. "Women who are physically active may also have more confidence in their own ability to continue with family-related, household, work-related, ...]]> http://www.medindia.net/news/exercise-reduces-fatigue-and-depression-in-breast-cancer-patients-100088-1.htm http://www.medindia.net/news/panel-recommends-use-of-ultrasound-machines-to-screen-for-breast-cancer-100038-1.htm A US Food and Drug Administration advisory panel has recommended that the agency approve the widespread use of automated ultrasound machines in screening for breast cancer. The FDA's Radiological Devices Panel of the Medical Devices Advisory Committee looked into the safety and effectiveness of Automated Breast Ultrasound (ABUS), manufactured by U-Systems, and found that the machines provide detailed image of dense breast tissue to the doctors, allowing them to spot cancerous tumors. Experts predict ...]]> http://www.medindia.net/news/panel-recommends-use-of-ultrasound-machines-to-screen-for-breast-cancer-100038-1.htm http://www.medindia.net/news/study-says-breast-cancer-treatment-side-effects-may-last-for-years-100005-1.htm In a recent study it was found that breast cancer patients suffer treatment-related side effects long after completing care. The findings are part of a special issue of Cancer devoted to exploring the physical late effects of breast cancer treatment and creating strategies to prevent, monitor for, and treat these conditions in the nation's 2.6 million survivors of the disease. "Our work provides the first accounting of the true magnitude of the post-treatment problems suffered by breast cancer ...]]> http://www.medindia.net/news/study-says-breast-cancer-treatment-side-effects-may-last-for-years-100005-1.htm http://www.medindia.net/news/spider-venom-and-breast-cancer-cure-99955-1.htm A group of Australian researchers are currently testing whether spider venom can provide a cure for breast cancer. Researchers at James Cook University in Queensland have been awarded a (Dollor) 200,000 grant from the National Breast Cancer Foundation to conduct a study looking into whether tarantula and funnel web spiders' venom can be used to develop an effective breast cancer cure. The study will be headed by Professor Norelle Daly who revealed that she and her team will be looking to find a molecule that can kill off the cancer cells....]]> http://www.medindia.net/news/spider-venom-and-breast-cancer-cure-99955-1.htm http://www.medindia.net/news/cell-and-animal-model-of-inflammatory-breast-cancer-developed-99945-1.htm Inflammatory breast cancer (IBC)is diagnosed more frequently in younger women than in older ones. It is also a very aggressive and often misunderstood type of cancer. The five-year survival rate is between 25 and 50 percent-significantly lower than the survival rate for other types of breast cancer. The reason for the poor prognosis is that IBC usually grows rapidly and often spreads quickly to other parts of the body, including the brain, bone and lymph nodes. In an effort to better understand ...]]> http://www.medindia.net/news/cell-and-animal-model-of-inflammatory-breast-cancer-developed-99945-1.htm http://www.medindia.net/news/presentation-of-triple-negative-breast-cancer-influenced-by-race-99944-1.htm Race may play a significant role in the presentation of triple-negative breast cancer among Hispanic women as a new study has found that Hispanic women in Puerto Rico who have triple-negative breast cancer share similar disease characteristics with Hispanic women in California. These study results were presented at the AACR Annual Meeting 2012, held here March 31 - April 4. "We think the fact that our patients are geographically located outside the mainland and still have the same disease ...]]> http://www.medindia.net/news/presentation-of-triple-negative-breast-cancer-influenced-by-race-99944-1.htm http://www.medindia.net/news/multiple-facets-of-deadly-breast-cancer-identified-99906-1.htm A discovery that will change the way the most deadly form of breast cancer is treated has been discovered by an international team of scientists, including four at Simon Fraser University. The journal INature/I has just published the team's findings online in the paper The clonal and mutational evolution spectrum of primary triple negative breast cancers. The study is the largest genetic analysis of what were thought to be triple negative breast cancer tumours. The 59 scientists ...]]> http://www.medindia.net/news/multiple-facets-of-deadly-breast-cancer-identified-99906-1.htm http://www.medindia.net/news/research-finds-function-link-between-two-causes-of-breast-cancer-treatment-failure-99904-1.htm A functional link between two major causes of treatment failure in breast cancer has been identified in research from The Cancer Institute of New Jersey (CINJ). The research shows that the protein behind one of these causes plays a role in increasing the drug resistance properties of the other. The work, which investigators say could help to identify targeted therapies, is being presented in abstract form at the Annual Meeting of the American Association for Cancer Research (AACR) being held in Chicago this week....]]> http://www.medindia.net/news/research-finds-function-link-between-two-causes-of-breast-cancer-treatment-failure-99904-1.htm http://www.medindia.net/news/false-positive-mammography-results-and-the-risk-of-breast-cancer-99815-1.htm New research indicates that false-positive mammograms may indicate an underlying pathology that could result in breast cancer in future. The study is published April 5 in the iJournal of the National Cancer Institute/i. Screening mammography is associated with false-positive test results in disease-free women, and those women are usually referred back for routine screening after the initial diagnostic work-up does not reveal cancer. Suspicious findings on screenings leading to false-positives ...]]> http://www.medindia.net/news/false-positive-mammography-results-and-the-risk-of-breast-cancer-99815-1.htm http://www.medindia.net/news/using-injectable-contraceptives-double-breast-cancer-risk-99797-1.htm A new study has revealed that young women who use injectable form of progestin-only birth control are twice at risk of developing breast cancer. While the contraceptive, called depo-medroxyprogesterone acetate, or DMPA, contains the same kind of progestin as the menopausal hormone-therapy regimen found by a Women's Health Initiative clinical trial to increase breast cancer risk among postmenopausal women, few studies have evaluated the link between DMPA use and breast cancer risk in younger women....]]> http://www.medindia.net/news/using-injectable-contraceptives-double-breast-cancer-risk-99797-1.htm http://www.medindia.net/news/combination-therapy-may-not-help-in-treatment-of-endocrine-resistant-breast-cancer-cells-99744-1.htm Researchers at Georgetown Lombardi Comprehensive Cancer Center have warned that a new class of agents known as c-Src inhibitors should not be used in combination with estrogen to treat endocrine resistant breast cancer. That's because their new study, being reported at the American Association for Cancer Research (AACR) Annual Meeting 2012, shows that using estrogen and a c-Src inhibitor, PP2, cancel each other out. The benefit once seen in using estrogen was gone once PP2, an inhibitor of the ...]]> http://www.medindia.net/news/combination-therapy-may-not-help-in-treatment-of-endocrine-resistant-breast-cancer-cells-99744-1.htm http://www.medindia.net/news/vitamin-d-and-breast-cancer-risk-99727-1.htm In African American women, variations in vitamin D receptor is associated with an increased breast cancer risk, shows study published in journal Breast Cancer Research. When a team of researchers led by Dr Song Yao and Dr Christine Ambrosone, from Roswell Park Cancer Institute, compared levels of vitamin D in the blood of women with or without breast cancer they found that severe vitamin D deficiency in African American women was almost six times more common than in European American women....]]> http://www.medindia.net/news/vitamin-d-and-breast-cancer-risk-99727-1.htm http://www.medindia.net/news/removing-good-cholesterol-receptor-may-fight-breast-cancer-99712-1.htm Eliminating a lipoprotein receptor known as SR-BI may help protect against breast cancer, suggest new findings presented at the American Association for Cancer Research Annual Meeting 2012 by Jefferson's Kimmel Cancer Center researchers. In vitro and mouse studies revealed that depletion of the SR-BI resulted in a decrease in breast cancer cell growth. SR-BI is a receptor for high-density lipoproteins (HDL) that are commonly referred to as "good cholesterol" because they help transport cholesterol ...]]> http://www.medindia.net/news/removing-good-cholesterol-receptor-may-fight-breast-cancer-99712-1.htm http://www.medindia.net/news/study-finds-some-vegetables-improve-breast-cancer-survival-99685-1.htm A US study presented on Tuesday showed Chinese women who ate cabbage, broccoli and leafy greens lived healthy and longer with improved survival rates after breast cancer than women who did not eat these cruciferous vegetables. The findings came from data on 4,886 Chinese breast cancer survivors age 20-75 who were diagnosed with stage one to stage four breast cancer from 2002 to 2006 and who were part of the Shanghai Breast Cancer Survival study. Women who ate more cruciferous vegetables ...]]> http://www.medindia.net/news/study-finds-some-vegetables-improve-breast-cancer-survival-99685-1.htm http://www.medindia.net/news/soy-risk-to-breast-cancer-patients-99640-1.htm Soy consumption may pose risks to breast cancer patients by making breast cancer tumors resistant to treatment, reveals US study. A study on lab rats showed that those who were fed a soy compound all their lives responded well to a popular breast cancer drug, tamoxifen, but those who began eating it as adults, and after they developed breast cancer, grew resistant. The research suggests a possible reason why tamoxifen stops working and allows tumors to grow again in some women, said ...]]> http://www.medindia.net/news/soy-risk-to-breast-cancer-patients-99640-1.htm http://www.medindia.net/news/routine-mammography-screening-may-result-in-overdiagnosis-of-breast-cancer-99634-1.htm Routine mammograms may lead to overdiagnosis of invasive breast cancer, shows study. The study appears in the April 3, 2012 issue of the IAnnals of Internal Medicine/I. "Mammography might not be appropriate for use in breast cancer screening because it cannot distinguish between progressive and non-progressive cancer," said lead author Mette Kalager, a visiting scientist at HSPH and a researcher at the Telemark Hospital in Norway. "Radiologists have been trained to find even the ...]]> http://www.medindia.net/news/routine-mammography-screening-may-result-in-overdiagnosis-of-breast-cancer-99634-1.htm http://www.medindia.net/news/hrt-linked-to-breast-cancer-once-again-99629-1.htm A new study conducted by a group of American researchers has found that prolonged use of any type of hormones to ease the symptoms of menopause can increase the risk of breast cancer. While taking pills that combine estrogen and progestin is often used in treating menopause symptoms, recent studies have shown that such treatments increase the risk of breast cancer. Taking estrogen pills was assumed to be safe among women who no longer have a uterus. However researchers from Brigham and Women's ...]]> http://www.medindia.net/news/hrt-linked-to-breast-cancer-once-again-99629-1.htm http://www.medindia.net/news/study-links-metastatic-breast-cancer-and-arthritis-99611-1.htm Relationship between metastatic breast cancer and autoimmune arthritis has been identified in a recent study. "Epidemiological studies have implied that breast cancer survival is significantly lower in patients who also had autoimmune arthritis," noted Pinku Mukherjee, Irwin Belk Distinguished Scholar of Cancer Research at UNC Charlotte, whose lab conducted the experiments. "As there is no obvious reason this should be so, we were interested in exploring possible cancer mechanisms that might explain why....]]> http://www.medindia.net/news/study-links-metastatic-breast-cancer-and-arthritis-99611-1.htm http://www.medindia.net/news/research-identifies-mechanism-behind-invasive-breast-cancer-99529-1.htm A new study has identified a key mechanism that causes breast cancer to spread. The research, published by Cell Press on March 30th in the journal IMolecular Cell/I, enhances our knowledge about the signals that drive cancer metastasis and identifies new therapeutic targets for a lethal form of invasive breast cancer that is notoriously resistant to treatment. Amplification of the gene for ErbB2 has been linked with aggressive forms of breast cancer and is associated with a poor outcome....]]> http://www.medindia.net/news/research-identifies-mechanism-behind-invasive-breast-cancer-99529-1.htm http://www.medindia.net/news/new-gene-linked-to-breast-cancer-risk-identified-99520-1.htm Mutations in a gene called XRCC2 may lead to increased breast cancer risk, according to a new study. The study looked at families that have a history of the disease but do not have mutations in the currently known breast cancer susceptibility genes. Sean Tavtigian, Ph.D., a Huntsman Cancer Institute (HCI) investigator and associate professor in the Department of Oncological Sciences at the University of Utah (U of U) is one of three co-principal investigators on the study, along with David Goldgar, Ph....]]> http://www.medindia.net/news/new-gene-linked-to-breast-cancer-risk-identified-99520-1.htm