http://www.medindia.net/healthnews/Pancreatic-Cancer-news.asp Medindia largest health website in india. en-us Copyright 2012. All Rights Reserved. Fri, 25 May 2012 06:49:43 GMT http://www.medindia.net/news/novel-pancreatic-cancer-vaccine-shows-promise-in-improving-survival-101622-1.htm A new pancreatic cancer vaccine shows promise in improving survival when added to standard treatment, say researchers from the University Hospitals Case Medical Center's Seidman Cancer Center and Case Western Reserve University School of Medicine. The Phase 2 data was presented at the Annual Meeting of the Society for Surgery of the Alimentary Tract, part of Digestive Disease Week in San Diego. In the plenary session titled "Addition of Algenpantucel-L Immunotherapy to Standard Adjuvant Therapy ...]]> http://www.medindia.net/news/novel-pancreatic-cancer-vaccine-shows-promise-in-improving-survival-101622-1.htm http://www.medindia.net/news/researchers-identify-early-biomarker-for-pancreatic-cancer-101307-1.htm New biomarker for pancreatic cancer has been discovered by researchers. The paper will be published May 15 in iCancer Research/i. Pancreatic ductal adenocarcinoma, or PDAC, is the fourth-leading cause of cancer-related death. Newly diagnosed patients have a median survival of less than one year, and a 5-year survival rate of only 3 to 5 percent. Therefore, biomarkers that can identify early onset of PDAC and which could be viable drug targets are desperately needed. a"We found ...]]> http://www.medindia.net/news/researchers-identify-early-biomarker-for-pancreatic-cancer-101307-1.htm http://www.medindia.net/news/mutant-kras-compels-pancreatic-cancer-upkeep-by-metabolic-pathways-100716-1.htm A genetic mutation coercing the launch of pancreatic cancer also fudges metabolic pathways to support tumour growth and progression, scientists report in the journal iCell/i. This newly discovered role for the Kras oncogene opens up a new category of potential targets for thwarting the influential mutation, which has proved difficult to attack directly, said study co-lead author Haoqiang Ying, Ph.D., instructor in The University of Texas MD Anderson Cancer Center Department of Genomic Medicine....]]> http://www.medindia.net/news/mutant-kras-compels-pancreatic-cancer-upkeep-by-metabolic-pathways-100716-1.htm http://www.medindia.net/news/gene-that-inhibits-pancreatic-cancer-spread-identified-100699-1.htm A gene that inhibits the spread of pancreatic cancer tumours has been discovered by scientists. This key finding paves way for targeted treatment of one of the deadliest forms of the disease. After discovering the gene dubbed USP9X at work in a study of pancreatic cancer in mice, the international research team found it also played a role in humans. "We looked in human tumour specimens and we found that it was missing in a fraction of patients -- the patients that did very poorly ....]]> http://www.medindia.net/news/gene-that-inhibits-pancreatic-cancer-spread-identified-100699-1.htm http://www.medindia.net/news/rectal-indomethacin-is-effective-in-reducing-post-ercp-pancreatitis-100550-1.htm bThe researchers from the University of Michigan Health System and Indiana University Medical Centre have reported in a study published in the NEJM (New England Journal of Medicine) that the frequency of pancreatitis after ERCP was significantly reduced if indomethacin was given rectally to the patients./b Endoscopic retrograde cholangiopancreatography (ERCP) is a non-invasive procedure used commonly for the diagnosis and treatment of bile and pancreatic duct problems. In an ERCP procedure, ...]]> http://www.medindia.net/news/rectal-indomethacin-is-effective-in-reducing-post-ercp-pancreatitis-100550-1.htm http://www.medindia.net/news/single-dose-drug-cuts-pancreatitis-risk-after-gastrointestinal-procedure-100049-1.htm A single dose of medication can significantly reduce the risk of pancreatitis after the endoscopic retrograde cholangiopancreatography (ERCP), a procedure commonly used to diagnose and treat problems of the bile and pancreatic ducts. The finding is significant in helping patients avoid a condition known as post-ERCP pancreatitis, a disabling complication that affects up to 1 in 4 high-risk patients who undergo the gastrointestinal procedure. Despite decades of research, this clinical trial ...]]> http://www.medindia.net/news/single-dose-drug-cuts-pancreatitis-risk-after-gastrointestinal-procedure-100049-1.htm http://www.medindia.net/news/vaccine-therapy-linked-to-stable-disease-in-pancreatic-cancer-99936-1.htm Stable disease in patients who are not candidates for surgery suggests being linked to a series of vaccine injections administered directly into a pancreatic cancer tumor according to research from The Cancer Institute of New Jersey (CINJ). Early results of a clinical trial being conducted at CINJ are being presented as a "highly-rated poster" at the Annual Meeting of the American Association for Cancer Research (AACR) being held in Chicago this week. CINJ is a Center of Excellence of the University ...]]> http://www.medindia.net/news/vaccine-therapy-linked-to-stable-disease-in-pancreatic-cancer-99936-1.htm http://www.medindia.net/news/mice-study-nutritional-supplement-may-inhibit-growth-of-pancreatic-cancer-cells-99844-1.htm A Mayo Clinic study has found that gamma-linoleic acid can inhibit the growth of a subset of pancreatic cancer cells in mice. The dietary supplement can also selectively promote cancer cell death in mice. The supplement, a fatty acid also known as GLA, worked particularly well when combined with the chemotherapy drug gemcitabine, the researchers say. The findings were presented today by Mayo Clinic pathologist Ruth Lupu, Ph.D., at the American Association for Cancer Research (AACR) Annual Meeting 2012....]]> http://www.medindia.net/news/mice-study-nutritional-supplement-may-inhibit-growth-of-pancreatic-cancer-cells-99844-1.htm http://www.medindia.net/news/potent-biomarker-for-pancreatic-cancer-identified-99697-1.htm Survivin protein serves as a useful tool in understanding pancreatic cancer, say scientists. In a recent study of pancreatic cancer patients who had undergone tumor resection, the scientists found that patients who underwent different treatment regimens, following surgery, had different levels of survivin and experienced different lengths of disease-free survival. "Biomarkers for pancreatic cancer are especially useful because the survival is so poor and it's such a bad disease for people to get," says Saad Khan, M....]]> http://www.medindia.net/news/potent-biomarker-for-pancreatic-cancer-identified-99697-1.htm http://www.medindia.net/news/pancreatic-cancer-prognosis-in-diabetic-patients-can-be-improved-by-metformin-99661-1.htm A new study indicates that metformin may improve survival in patients with diabetes and pancreatic cancer. The study is published in iClinical Cancer Research/i, a journal of the American Association for Cancer Research. Although the causes of pancreatic cancer remain largely unknown, patients with pancreatic cancer often have a high prevalence of diabetes and impaired glucose tolerance. "This study suggests that metformin use in patients with diabetes was associated with improved ...]]> http://www.medindia.net/news/pancreatic-cancer-prognosis-in-diabetic-patients-can-be-improved-by-metformin-99661-1.htm http://www.medindia.net/news/pancreatic-cancer-patients-find-electrical-pulse-treatment-promising-99472-1.htm Ray of hope for people with inoperable locally advanced pancreatic cancer (LAPC) according to results of a study presented at the Society of Interventional Radiology's 37th Annual Scientific Meeting in San Francisco, California. A new procedure called irreversible electroporation or IRE uses microsecond electrical pulses to force open and destroy tumor cells around a vast and delicate network of blood vessels of the pancreas. The technique has been successful in treating primary and metastatic ...]]> http://www.medindia.net/news/pancreatic-cancer-patients-find-electrical-pulse-treatment-promising-99472-1.htm http://www.medindia.net/news/novel-protein-regulates-spread-of-pancreatic-cancer-cells-99312-1.htm University of London researchers have discovered a new protein that makes pancreatic cancer cells less sticky and regulates the spread of pancreatic cancer cells. The protein, known as S100PBP, does this by suppressing a second protein called cathepsin Z. The research team has shown that cathepsin Z makes pancreatic cancer cells sticky, allowing them to spread to their surrounding environment. Prior to this study nothing was known about the function of S100PBP in the body or the role that cathepsin Z plays in pancreactic cancer....]]> http://www.medindia.net/news/novel-protein-regulates-spread-of-pancreatic-cancer-cells-99312-1.htm http://www.medindia.net/news/outcomes-for-patients-with-infected-severe-pancreatitis-improved-by-endoscopic-procedure-99078-1.htm Patients with infected necrotizing pancreatitis who underwent endoscopic transgastric necrosectomy had an associated lower risk of major complications and death compared to patients who had surgical necrosectomy, a new study has found.The study appears in the March 14 issue of iJAMA/i. "Acute pancreatitis is a common and potentially lethal disorder. In the United States alone, more than 50,000 patients are admitted with acute pancreatitis each year. One of the most dreaded complications ...]]> http://www.medindia.net/news/outcomes-for-patients-with-infected-severe-pancreatitis-improved-by-endoscopic-procedure-99078-1.htm http://www.medindia.net/news/pancreas-cancer-treatment-challenges-addressed-by-scientists-99077-1.htm Pancreatic tumors are the deadliest of cancers as they can spread quickly and are notoriously resistant to treatment. Their resistance to chemotherapy stems in part from a unique biological barrier the tumor builds around itself. Now scientists at Fred Hutchinson Cancer Research Center have found a way to break through that defense, and their research represents a potential breakthrough in the treatment of pancreas cancer. In a paper to be published in the March 20 issue of iCancer Cell/i, senior author Sunil Hingorani, M....]]> http://www.medindia.net/news/pancreas-cancer-treatment-challenges-addressed-by-scientists-99077-1.htm http://www.medindia.net/news/genes-that-may-cause-pancreatic-cancer-identified-98751-1.htm Researchers have identified more than 500 genes that cause or contribute to the development of pancreatic cancer. This particularly deadly disease has a 1-in-20 survival rate after five years, largely because no effective genetic screening method exists for early detection. Principal investigators Nancy Jenkins, Ph.D., and Neal Copeland, Ph.D., report in the iProceedings of the National Academy of Sciences/i, online soon, that the vast majority of the 543 genes they identify in mouse ...]]> http://www.medindia.net/news/genes-that-may-cause-pancreatic-cancer-identified-98751-1.htm http://www.medindia.net/news/laser-light-technology-to-treat-prostate-pancreatic-cancer-97689-1.htm Lund University scientists are in the process of using laser light technology in combination with certain drugs to treat prostate and pancreatic cancer. "I think we are about to see a real breakthrough, both for us and for other research groups around the world who conduct research on cancer treatment using laser light", says Johannes Swartling, Doctor of Atomic Physics at Lund University and Chief Technical Officer at SpectraCure, the company that is now developing the software. The ...]]> http://www.medindia.net/news/laser-light-technology-to-treat-prostate-pancreatic-cancer-97689-1.htm http://www.medindia.net/news/using-pancreas-to-taste-fructose-97203-1.htm The tongue's taste receptors aids in telling apart between safe food and spoilt food or toxic. Nevertheless taste receptors are now being discovered in other organs, also. In a study published online the week of February 6 by the iProceedings of the National Academy of Sciences/i of the USA, researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) discovered that beta cells in the pancreas use taste receptors to sense fructose, a type of sugar. According to the study, the ...]]> http://www.medindia.net/news/using-pancreas-to-taste-fructose-97203-1.htm http://www.medindia.net/news/researchers-identify-gene-that-triggers-pancreatic-cancer-growth-97122-1.htm A mutant protein that plays key role in pancreatic cancer development and growth has been identified by researchers. The finding from the University of Michigan Comprehensive Cancer Center suggests a possible target for developing new ways to treat this deadly disease. When Kras is turned off, early stage precancerous pancreatic lesions transform into normal pancreas cells. Researchers have known that mutations in the Kras gene are what cause pancreatic cancer to develop. These ...]]> http://www.medindia.net/news/researchers-identify-gene-that-triggers-pancreatic-cancer-growth-97122-1.htm http://www.medindia.net/news/pancreatic-cancer-triggered-by-mutated-kras-gene-96800-1.htm The connection between two signature characteristics of pancreatic cancer has been identified by scientists. They have thus zeroed in on a self-perpetuating "vicious cycle" of molecular activity and a new potential target for drugs to treat one of the most lethal forms of cancer. The research, reported in the journal ICancer Cell/I and led by scientists at The University of Texas MD Anderson Cancer Center, connected the molecular dots between: ulliMutated versions of Kras, a gene ...]]> http://www.medindia.net/news/pancreatic-cancer-triggered-by-mutated-kras-gene-96800-1.htm http://www.medindia.net/news/research-sheds-light-on-metastasis-of-pancreatic-cancer-96544-1.htm Pancreatic cancer cells in an animal model begin to spread before clinically obvious tumor tissue is detected, says a new research by Ben Stanger, MD, PhD, assistant professor of Medicine in the Division of Gastroenterology at the Perelman School of Medicine, University of Pennsylvania, and Andrew Rhim, MD, a Gastroenterology Fellow in the Stanger lab. What's more, they showed that inflammation enhances cancer progression in part by facilitating a cellular transformation that leads to entry of cancer cells into the circulation....]]> http://www.medindia.net/news/research-sheds-light-on-metastasis-of-pancreatic-cancer-96544-1.htm http://www.medindia.net/news/Gene-Mutation-Behind-Hereditary-Pancreatic-Cancer-Identified-95467-1.htm Researchers have found that the mutations in the ATM gene may increase the hereditary risk for developing pancreatic cancer. Pancreatic cancer is one of the most morbid cancers, with less than 5 percent of those diagnosed with the disease surviving to five years. Approximately 10 percent of patients come from families with multiple cases of pancreatic cancer. "There was significant reason to believe this clustering was due to genetics, but we had not, to this point, been able to find the ...]]> http://www.medindia.net/news/Gene-Mutation-Behind-Hereditary-Pancreatic-Cancer-Identified-95467-1.htm http://www.medindia.net/news/Compound-Found-In-Virgin-Olive-Oil-And-Fish-May-Prevent-Acute-Pancreatitis-95254-1.htm A new study has found that fatty acids present in virgin oil and fish may help alleviate symptoms of acute pancreatitis. The researchers at the University of Granada Physiology Department evaluated the role of Mediterranean diet ingredients in the prevention and mitigation of cell damage. Oleic acid and hydroxytyrosol, present in a particularly high concentration in virgin olive oil and n-3 polyunsaturated fatty acids found in fish affect the cellular mechanisms involved in the development ...]]> http://www.medindia.net/news/Compound-Found-In-Virgin-Olive-Oil-And-Fish-May-Prevent-Acute-Pancreatitis-95254-1.htm http://www.medindia.net/news/Pancreatic-Cancer-and-Trace-Elements-95033-1.htm Nickel and selenium in body may lower pancreatic cancer risk, shows research published online in IGut/I. Similarly, high levels of lead, arsenic, and cadmium could boost the likelihood of developing the disease, the study shows. The researchers assessed 12 trace element levels in the toenails of 118 patients with exocrine pancreatic cancer-the most common form of the disease-and just under 400 hospital patients without cancer. Nails, and particularly toenails, are considered ...]]> http://www.medindia.net/news/Pancreatic-Cancer-and-Trace-Elements-95033-1.htm http://www.medindia.net/news/Distorted-Insulin-Signaling-Observed-in-Pancreas-of-Type-2-Diabetics-94816-1.htm A new study has demonstrated that insulin signaling is altered in the pancreas. The errant signals disrupt both the number and quality of beta cells - the cells that produce insulin. The finding is described in the journal iPLoS ONE/i. Franco Folli, M.D., Ph.D., of the School of Medicine at The University of Texas Health Science Center San Antonio, and Rohit Kulkarni, M.D., Ph.D., of the Joslin Diabetes Center, Harvard Medical School, Boston, are principal investigators of the study....]]> http://www.medindia.net/news/Distorted-Insulin-Signaling-Observed-in-Pancreas-of-Type-2-Diabetics-94816-1.htm http://www.medindia.net/news/New-Insight-into-Development-of-the-Pancreas-94658-1.htm A rare genetic disorder gives surprising insight into how the pancreas develops, says study. The finding provides a clue to how it may be possible to 'programme' stem cells - master cells in the body that can develop into specialised cells - to become pancreatic cells. Pancreatic agenesis is a rare condition in which the body is unable to produce a pancreas. The pancreas plays an essential role in regulating levels of sugar (glucose) in the blood. It does this by the release of the hormone ...]]> http://www.medindia.net/news/New-Insight-into-Development-of-the-Pancreas-94658-1.htm http://www.medindia.net/news/New-Stem-Cell-Production-Process-Create-Scalable-Amounts-of-Liver-and-Pancreas-Precursor-Cells-94358-1.htm Barrier broken in developing regenerative treatments for diabetes and liver disease with a method to produce medically handy amounts of endoderm cells from human pluripotent stem cells by scientists in Canada. The research, published in IBiotechnology and Bioengineering/I, can be transferred to other areas of stem cell research helping scientists to navigate the route to clinical use known as the 'valley of death'. "One million people suffer from type 1 diabetes in the United States, while ...]]> http://www.medindia.net/news/New-Stem-Cell-Production-Process-Create-Scalable-Amounts-of-Liver-and-Pancreas-Precursor-Cells-94358-1.htm http://www.medindia.net/news/FDA-Calls-for-Speeding-Up-Development-of-Next-Gen-Artificial-Pancreas-94219-1.htm The US Food and Drug Administration asked researchers working on the next generation artificial pancreatic device for diabetes patients to speed up the delivery of the device but said that the device makers will have to abide by the new set of guidelines for its approval in the United States. Researchers are working on an artificial pancreas that will do away with the need to continuously monitor blood sugar levels for Type 1 diabetic patients. The device works by monitoring the glucose levels ...]]> http://www.medindia.net/news/FDA-Calls-for-Speeding-Up-Development-of-Next-Gen-Artificial-Pancreas-94219-1.htm http://www.medindia.net/news/Pancreatic-Cancer-may-be-Driven-by-Embryonic-Signal-92999-1.htm Pancreatic cancer has a tendency of spreading quickly and also harbors cancer stem cells that stubbornly resist conventional approaches to therapy. Now, researchers reporting in the November issue of ICell Stem Cell/I, a Cell Press publication, have evidence to suggest there is a way to kill off those cancer stem cells. The target is a self-renewal pathway known for its role not in cancer but in embryonic stem cells. "I don't think the cancer stem cells have any direct link to embryonic ...]]> http://www.medindia.net/news/Pancreatic-Cancer-may-be-Driven-by-Embryonic-Signal-92999-1.htm http://www.medindia.net/news/Complications-of-Acute-Pancreatitis-in-Obese-Patients-Linked-to-Breakdown-of-Unsaturated-Fats-92950-1.htm Researchers at the University of Pittsburgh School of Medicine have revealed that toxic byproducts produced by the breakdown of unsaturated fats lead to a higher likelihood of severe inflammation, cell death and multi-system organ failure among acute pancreatitis patients who are obese. Their findings, published online today in Science iTranslational Medicine/i, provide new insight into how fat can induce complications after sudden inflammatory, non-infectious illnesses. Doctors have ...]]> http://www.medindia.net/news/Complications-of-Acute-Pancreatitis-in-Obese-Patients-Linked-to-Breakdown-of-Unsaturated-Fats-92950-1.htm http://www.medindia.net/news/Certain-Mouth-Bacteria-May-Actually-Be-Indicating-Pancreatic-Cancer-91967-1.htm Particular types of mouth bacteria, some of which are found in gum disease, are associated with the development of pancreatic cancer, indicates a small study published online in the journal iGut/i. The finding opens up the possibility of curbing the progress of one of the most difficult cancers to treat, by altering the balance of bacteria, say the authors. Pancreatic cancer usually spreads very quickly, and only around one in 20 patients is still alive five years after diagnosis. The ...]]> http://www.medindia.net/news/Certain-Mouth-Bacteria-May-Actually-Be-Indicating-Pancreatic-Cancer-91967-1.htm http://www.medindia.net/news/New-Diabetes-Drugs-Possible-After-Discovery-of-Insulin-Switches-in-Pancreas-91175-1.htm The way in which a hormone turns on a series of molecular switches inside the pancreas that increases production of insulin has been discovered by researchers at the Salk Institute. The finding, published today in the IProceedings of the National Academy of Sciences/I, raises the possibility that new designer drugs might be able to turn on key molecules in this pathway to help the 80 million Americans who have type 2 diabetes or pre-diabetic insulin resistance. The molecular switches ...]]> http://www.medindia.net/news/New-Diabetes-Drugs-Possible-After-Discovery-of-Insulin-Switches-in-Pancreas-91175-1.htm http://www.medindia.net/news/EGFR-Gene-Essential-for-Pancreatic-Cancer-Development-Study-90779-1.htm The epidermal growth factor receptor (EGFR) gene is vital for the development of pancreatic cancer, reveals study presented at the Second AACR International Conference on Frontiers in Basic Cancer Research. The mutation of the KRAS gene has been found to be an important component in the development of many cancers, including pancreatic cancer. However, Barbara M. Gruener, researcher at the Technical University in Munich, Germany, said that despite the presence of KRAS, the development of ...]]> http://www.medindia.net/news/EGFR-Gene-Essential-for-Pancreatic-Cancer-Development-Study-90779-1.htm http://www.medindia.net/news/Virus-Holds-Promise-for-Imaging-and-Treating-Pancreatic-Cancer-90755-1.htm Researchers are investigating a potential treatment and noninvasive imaging modality for pancreatic cancer that shows promise, according to researchers at Memorial Sloan-Kettering Cancer Center in New York, N.Y., and Genelux Corporation in San Diego, Calif. The vaccinia virus construct GLV-1h153, engineered to encode for the human sodium iodide symporter gene (hNIS), is a promising candidate for viro-therapy of cancer and for long-term noninvasive monitoring of therapeutic response via deep ...]]> http://www.medindia.net/news/Virus-Holds-Promise-for-Imaging-and-Treating-Pancreatic-Cancer-90755-1.htm http://www.medindia.net/news/Two-New-Type-2-Diabetes-Drugs-Increase-Pancreatic-Cancer-Risk-90713-1.htm A study by UCLA has found that two new drugs used to treat Type 2 diabetes could significantly increase the risk of developing pancreatitis and pancreatic and thyroid cancer. Researchers from the Larry L. Hillblom Islet Research Center at UCLA examined the U.S. Food and Drug Administration's database for adverse events reported between 2004 and 2009 among patients using the drugs sitagliptin and exenatide. They found a six-fold increase in the odds ratio for reported cases of pancreatitis with ...]]> http://www.medindia.net/news/Two-New-Type-2-Diabetes-Drugs-Increase-Pancreatic-Cancer-Risk-90713-1.htm http://www.medindia.net/news/Zinc-May-Help-Suppress-Pancreatic-Cancer-Cells-89713-1.htm Zinc has been shown to be a likely tumor suppressor in the commonest form of pancreatic cancer by scientists from University of Maryland. "The report establishes for the first time, with direct measurements in human pancreatic tissue, that the level of zinc is markedly lower in pancreatic adenocarcinoma cells as compared with normal pancreas cells," said lead author Leslie Costello, PhD, professor, Department of Oncology and Diagnostic Sciences, University of Maryland School of Dentistry (SOD)....]]> http://www.medindia.net/news/Zinc-May-Help-Suppress-Pancreatic-Cancer-Cells-89713-1.htm http://www.medindia.net/news/New-Imaging-Technique-to-Diagnose-Pancreatic-Cancer-89402-1.htm Near-infrared imaging system can reliably distinguish between pancreatic cysts that are low-risk and high-risk for becoming malignant. Other optical techniques often fail to provide images that are clear enough for doctors to differentiate between the two types. To test the diagnostic potential of OCT imaging, researchers from four Boston-area institutions led by Nicusor Iftimia from Physical Sciences, Inc. used the technique to examine surgically removed pancreatic tissue samples from patients with cystic lesions....]]> http://www.medindia.net/news/New-Imaging-Technique-to-Diagnose-Pancreatic-Cancer-89402-1.htm http://www.medindia.net/news/Study-Says-Blocking-Receptor-in-Key-Hormone-Fires-Up-Enzyme-to-Kill-Pancreatic-Cancer-Cells-88987-1.htm Blocking a receptor of a key hormone in the renin-angiotensin system (RAS) reduces cancer cell growth by activating the enzyme AMPK to inhibit fatty acid synthase, the ingredients to support cell division, pancreatic cancer researchers at Thomas Jefferson University have shown, for the first time. With that, a new chemopreventive agent that inhibits the angiotensin II type 2 receptor-never before thought to play a role in tumor growth-could be developed A HREF="http:www.jeffersonhospital.org/diseases-conditions/cancer-pancreatic....]]> http://www.medindia.net/news/Study-Says-Blocking-Receptor-in-Key-Hormone-Fires-Up-Enzyme-to-Kill-Pancreatic-Cancer-Cells-88987-1.htm http://www.medindia.net/news/Drinking-Spirits-Increase-Acute-Pancreatitis-Risk-Study-88696-1.htm Consuming just one large serving of spirits could increase the risk of acute pancreatitis, but wine or beer does not appear to have the same effect, according to a new study. To come to the conclusion, the researchers followed 84,601 people from 46 to 84 years of age from the general population in Vastmanland and Uppsala for a median of ten years. During that time 513 developed acute pancreatitis. "Our study revealed a steady increase between each measure of spirits a person drank on ...]]> http://www.medindia.net/news/Drinking-Spirits-Increase-Acute-Pancreatitis-Risk-Study-88696-1.htm http://www.medindia.net/news/Screening-For-Pancreatic-Cancer-In-High-Risk-Populations-Can-Be-Improved-Study-Opines-88266-1.htm Researchers from New England report in a new study that using a tumor marker, serum CA 19-9, combined with an endoscopic ultrasound if the tumor marker is elevated, is more likely to detect stage 1 pancreatic cancer in a high-risk population than by using the standard means of detection. The study appears in the July issue of iGIE: Gastrointestinal Endoscopy/i, the monthly peer-reviewed scientific journal of the American Society for Gastrointestinal Endoscopy (ASGE). Pancreatic cancer is ...]]> http://www.medindia.net/news/Screening-For-Pancreatic-Cancer-In-High-Risk-Populations-Can-Be-Improved-Study-Opines-88266-1.htm http://www.medindia.net/news/No-Link-Between-Cured-Meat-and-Pancreatic-Cancer-87278-1.htm A new study published in the American Journal of Epidemiology has found no evidence that eating cured meat increases the risk of pancreatic cancer. A number of recent studies have hinted that eating cured meat such as ham or hot dogs could increase the risk of cancer since the preservatives used in curing the meat are known to cause tumors in animals. However researchers from the National Cancer Institute polled over 300,000 adults regarding a 124-item food questionnaire and found that just over ...]]> http://www.medindia.net/news/No-Link-Between-Cured-Meat-and-Pancreatic-Cancer-87278-1.htm http://www.medindia.net/news/Chemical-Produced-in-Pancreas-can-Prevent-Reverse-Diabetes-87089-1.htm A chemical produced by the insulin producing beta cells in the pancreas was found to prevent or in some cases reverse Type 1 diabetes in mice, reveals study. Type 1 diabetes, earlier known as juvenile diabetes, is characterized by the immune system's destruction of the beta cells in the pancreas that are responsible for making and secreting insulin. Researchers at St. Michael's Hospital studied the role of GABA, or gamma-aminobutyric acid, an amino acid produced by beta cells in the pancreas to check its impact on diabetes....]]> http://www.medindia.net/news/Chemical-Produced-in-Pancreas-can-Prevent-Reverse-Diabetes-87089-1.htm http://www.medindia.net/news/Artificial-Pancreas-That-Will-Make-Daily-Insulin-Shots-History-On-the-Anvil-86857-1.htm Mayo Clinic endocrinologists Yogish Kudva, M.B.B.S., and Ananda Basu, M.B.B.S., M.D., have developed an artificial pancreas that will deliver insulin automatically and with an individualized precision. The development will relieve diabetic patients of painful finger pricks and daily insulin dosing. The "Closed Loop System" under development includes a blood sugar monitor, an automatic insulin pump, a set of activity monitors that attach to the body and a central processing unit. Clinical ...]]> http://www.medindia.net/news/Artificial-Pancreas-That-Will-Make-Daily-Insulin-Shots-History-On-the-Anvil-86857-1.htm http://www.medindia.net/news/FOLFIRINOX-Drug-Combination-Prolongs-Survival-in-Pancreatic-Cancer-Patients-85837-1.htm bA new drug chemotherapy combination - /bFOLFIRINOXb may boost survival of pancreatic cancer patients, suggests study./b bWith a very poor prognosis pancreatic cancer is responsible for 6% of all cancer-related deaths./b Ninety-five per cent of the people diagnosed with this cancer will not be alive 5 years later. Thus even an early diagnosis may not help in most cases. A recent study published in the New England Journal of Medicine, a leading medical journal, adds hope....]]> http://www.medindia.net/news/FOLFIRINOX-Drug-Combination-Prolongs-Survival-in-Pancreatic-Cancer-Patients-85837-1.htm http://www.medindia.net/news/New-Effective-Artificial-Pancreas-to-Improve-the-Life-of-Type-1-Diabetics-85171-1.htm A new study published in the British Medical Journal reveals that overnight closed loop delivery of insulin 'can operate safely, effectively, and consistently across different age groups, insulin sensitivities, and lifestyle conditions, including large evening meals and alcohol intake', for people with type-1 diabetes. BRBRAt present diabetes is one of the leading health concerns around the globe. Immense stress is being laid on analyzing the effect and resulting aftermaths of insulin therapy in diabetics....]]> http://www.medindia.net/news/New-Effective-Artificial-Pancreas-to-Improve-the-Life-of-Type-1-Diabetics-85171-1.htm http://www.medindia.net/news/Pancreatic-Cancer-Stem-Cells-Targeted-and-Killed-by-Oncolytic-Viruses-84803-1.htm New research from Memorial Sloan-Kettering Cancer Center in New York says that oncolytic viruses quickly infect and kill cancer stem cells, which may provide a treatment for tumors that are resistant to conventional chemotherapy and radiation, particularly pancreatic cancer. The findings are especially important since pancreatic cancer has a poor prognosis and is difficult to detect and treat at early stages. Investigators led by Joyce Wong, MD, surgical researcher with Memorial Sloan-Kettering ...]]> http://www.medindia.net/news/Pancreatic-Cancer-Stem-Cells-Targeted-and-Killed-by-Oncolytic-Viruses-84803-1.htm http://www.medindia.net/news/Novartis-Announces-FDA-Approval-for-Rare-Pancreatic-Cancer-Drug-84659-1.htm Swiss pharmaceutical giant Novartis has announced that its cancer drug Afinitor has received approval from the US Food and Drug Administration to be used in the treatment of a rare pancreatic cancer. Afinitor had earlier received unanimous backing by a US advisory panel to use the drug in treating advanced pancreatic neuroendocrine tumors even though one of the FDA officials had questioned Novartis' findings on whether the drug was beneficial or not. Novartis had narrowed down the benefits in ...]]> http://www.medindia.net/news/Novartis-Announces-FDA-Approval-for-Rare-Pancreatic-Cancer-Drug-84659-1.htm http://www.medindia.net/news/New-Test-to-Detect-Acute-Pancreatitis-84223-1.htm Univerity of Texas scientists have developed a faster, cheaper biosensor that aids in the detection of acute pancreatitis. The sensor, which could be produced for as little as a dollar, could help prevent damage from acute pancreatitis- a sudden inflammation of the pancreas that can lead to severe stomach pain, nausea, fever, shock and in some cases, death. It is built with a 12-cent LED light, aluminum foil, gelatin, milk protein and a few other cheap, easily obtainable materials. "We've ...]]> http://www.medindia.net/news/New-Test-to-Detect-Acute-Pancreatitis-84223-1.htm http://www.medindia.net/news/Artificial-Pancreas-Improves-Blood-Sugar-Control-83710-1.htm A new artificial pancreas currently being tested by researchers at University of Cambridge is reported to be effective in reducing the risk of low blood sugar and also improves blood sugar control. The study, led by Roman Hovorka, involved 24 people suffering from type 1 diabetes. The volunteers were divided into two groups of 12 each and were made to go through two real-life scenarios, one that involved eating dinner at home while the second scenario involved eating dinner, which involved drinking alcohol, in a restaurant....]]> http://www.medindia.net/news/Artificial-Pancreas-Improves-Blood-Sugar-Control-83710-1.htm http://www.medindia.net/news/Inflammation-And-Pancreatic-Cancer-Link-Discovered-UCSF-Scientists-83557-1.htm Solving part of a medical mystery, researchers at the University of California, San Francisco have established a link between molecules found in an inflamed pancreas and the early formation of pancreatic cancer - a discovery that may help scientists identify new ways to detect, monitor and treat this deadly disease. Scientists have known for many years that pancreatitis, a painfully inflamed pancreas, is a common risk factor for pancreatic cancer - along with things like smoking and diet. But nobody knew exactly why....]]> http://www.medindia.net/news/Inflammation-And-Pancreatic-Cancer-Link-Discovered-UCSF-Scientists-83557-1.htm http://www.medindia.net/news/New-Insight-into-Acute-Pancreatitis-83453-1.htm New findings by the researchers can keep acute pancreatitis, a common disease of the pancreas at bay. Researchers have found that time plays a key factor in the pancreatic disease. When the timing is right, those enzymes are activated only when they reach the gut, where they get to work releasing and distributing nutrients that we need to survive. If the timing is wrong and the enzymes are activated too soon, they break down the pancreas itself, which is painful and sometimes fatal. Fortunately, ...]]> http://www.medindia.net/news/New-Insight-into-Acute-Pancreatitis-83453-1.htm