http://www.medindia.net/healthnews/Oophorectomy-news.asp Medindia largest health website in india. en-us Copyright 2012. All Rights Reserved. Fri, 25 May 2012 06:43:47 GMT http://www.medindia.net/news/molecule-that-inhibits-estrogen-found-101215-1.htm A molecule that could lead to new therapies for preventing and treating endometrial and breast cancer and other estrogen-related diseases has been identified by researchers at Albert Einstein College of Medicine of Yeshiva University. The molecule, discovered in animal studies, inhibits the action of estrogen. This female hormone plays a key role in the growth, maintenance and repair of reproductive tissues, and fuels the development of endometrial and breast cancers. The hormones estradiol ...]]> http://www.medindia.net/news/molecule-that-inhibits-estrogen-found-101215-1.htm http://www.medindia.net/news/report-measuring-progesterone-receptor-expression-to-improve-hormone-receptor-positive-cancer-management-101019-1.htm Potential ways for doctors to improve the treatment of hormone receptor-positive breast cancer even if they lack access to costly multi-gene tests have been found by American and Spanish researchers. This was reported at the 4th IMPAKT Breast Cancer Conference. Because breast cancer is a biologically and clinically varied disease, doctors aim to choose appropriate treatments based on the characteristics of each patient's individual tumor. In the past, this has been done using pathology-based ...]]> http://www.medindia.net/news/report-measuring-progesterone-receptor-expression-to-improve-hormone-receptor-positive-cancer-management-101019-1.htm http://www.medindia.net/news/link-between-estrogen-and-tobacco-smoke-99680-1.htm A recent research shows clear association between estrogen and tobacco smoke. The hormone estrogen may help promote lung cancer-including compounding the effects of tobacco smoke on the disease. The researchers found that estrogen is metabolized into toxic derivatives in the mouse lung. The level of these toxic metabolites increased when mice were exposed to tobacco smoke. The results suggest that new therapies which prevent estrogen from being converted into toxins could one day help treat-or even prevent-lung cancer, says Peng....]]> http://www.medindia.net/news/link-between-estrogen-and-tobacco-smoke-99680-1.htm http://www.medindia.net/news/impact-of-estrogen-alone-vs-estrogen-plus-progestin-on-breast-cancer-risk-dr-rowan-chlebowski-99007-1.htm Over the last decade, results from large prospective cohort studies and the Women's Health Initiative (WHI) randomized placebo-controlled hormone therapy trials have significantly changed views on how estrogen alone and estrogen plus progestin influence the risk of breast cancer, states a review published TK in the IJournal of The National Cancer InstituteI. /IAlthough hormone therapy is currently used by millions of women for menopausal symptoms, there is still concern about hormone therapy-induced breast cancer risk....]]> http://www.medindia.net/news/impact-of-estrogen-alone-vs-estrogen-plus-progestin-on-breast-cancer-risk-dr-rowan-chlebowski-99007-1.htm http://www.medindia.net/news/estrogen-after-menopausal-hormone-therapy-lowers-breast-cancer-risk-98617-1.htm Estrogen-only form of menopausal hormone therapy reduces risk of breast cancer in some women, shows research published in The Lancet Oncology. A follow-up study of over 7,500 women from the Women's Health Initiative (WHI) trial who took estrogen for about 6 years and then stopped has found that they are over 20 percent less likely to develop breast cancer and remain significantly less likely to die from the disease than those who never used HRT, a period of nearly 5 years after stopping treatment....]]> http://www.medindia.net/news/estrogen-after-menopausal-hormone-therapy-lowers-breast-cancer-risk-98617-1.htm http://www.medindia.net/news/postmenopausal-osteoporosis-clinical-guide-on-selective-estrogen-receptor-modulators-98272-1.htm The publication of an important clinical guide from the European Menopause and Andropause Society (EMAS) in the February issue of IMaturitas/I has been announced by Elsevier, a world-leading provider of scientific, technical and medical information products and services. This clinical guide details the role of selective estrogen receptor modulators (SERMs) against postmenopausal osteoporosis as the European Medicines Agency (EMA) has approved the use of bazedoxifene and lasofoxifene. Postmenopausal ...]]> http://www.medindia.net/news/postmenopausal-osteoporosis-clinical-guide-on-selective-estrogen-receptor-modulators-98272-1.htm http://www.medindia.net/news/isolation-of-egg-producing-stem-cells-from-human-ovaries-98046-1.htm Researchers isolated egg-producing stem cells from human ovaries and these stem cells can produce normal egg cells. This finding could one day boost fertility treatment, says study. The work sweeps away the belief that a woman has only a limited stock of eggs and replaces it with the theory that the supply is continuously replenished from precursor cells in the ovary, its authors said. "The prevailing dogma in our field for the better part of the last 50 or 60 years was that young girls ...]]> http://www.medindia.net/news/isolation-of-egg-producing-stem-cells-from-human-ovaries-98046-1.htm http://www.medindia.net/news/periodontal-health-may-be-compromised-by-injectable-progesterone-contraceptives-97276-1.htm New research has indicated that injectable progesterone contraceptives may be associated with poor periodontal health. The research appears in the iJournal of Periodontology/i. The study found that women who are currently taking depotmedroxyprogesterone acetate (DMPA) injectable contraceptive, or have taken DMPA in the past, are more likely to have indicators of poor periodontal health, including gingivitis and periodontitis, than women who have never taken the injectable contraceptive. ...]]> http://www.medindia.net/news/periodontal-health-may-be-compromised-by-injectable-progesterone-contraceptives-97276-1.htm http://www.medindia.net/news/caffeine-intake-alters-estrogen-levels-in-asian-women-96667-1.htm Consumption of caffeine impacts Asian and white women differently. According to a new study, moderate intake of caffeine increases estrogen levels in Asian women, but lowers in whites. Researchers at the National Institutes of Health and colleagues found that Asian women who consumed an average of 200 milligrams or more of caffeine a day-the equivalent of roughly two cups of coffee-had elevated estrogen levels when compared to women who consumed less. However, white women who consumed 200 ...]]> http://www.medindia.net/news/caffeine-intake-alters-estrogen-levels-in-asian-women-96667-1.htm http://www.medindia.net/news/Vaginal-Progesterone-Prevents-Preterm-Birth-94862-1.htm Women with a short cervix should be treated with vaginal progesterone to prevent preterm birth, according to a landmark study by leading obstetricians around the world. Vaginal progesterone decreased the rate of preterm birth by 42%, and significantly reduced the rate of respiratory distress syndrome and the need for mechanical ventilation, as well as a composite of several complications of premature newborns (e.g. infection, necrotizing enterocolitis, intracranial hemorrhage, etc.). An early ...]]> http://www.medindia.net/news/Vaginal-Progesterone-Prevents-Preterm-Birth-94862-1.htm http://www.medindia.net/news/Combined-Hormone-Therapy-Worsens-Breast-Cancer-Risk-Over-Estrogen-Alone-93682-1.htm Wondering whether combination therapy of estrogen and progestin better or worse than just giving women estrogen alone adds to the already ongoing debate on using menopausal hormone therapies to relieve symptoms in post-menopausal women. In women who still have a uterus (those who have not had a hysterectomy), progestin counteracts the increased risk of uterus cancer when estrogen is given alone, but at the expense of an increase in breast cancer risk compared to estrogen alone. Now a study by ...]]> http://www.medindia.net/news/Combined-Hormone-Therapy-Worsens-Breast-Cancer-Risk-Over-Estrogen-Alone-93682-1.htm http://www.medindia.net/news/Risk-of-Breast-Cancer-in-Postmenopausal-Women-Increased-by-High-Estrogen-Levels-92418-1.htm Post-menopausal women with high levels of hormones such as estrogen or testosterone have a high risk of breast cancer, a new study has revealed. The study looked at eight different sex and growth hormones and found that the risk of breast cancer increased with the number of elevated hormones - each additional elevated hormone level increased risk by 16percent. The researchers from the Brigham and Women's Hospital and Harvard Medical School used blood samples collected from nurses up to ...]]> http://www.medindia.net/news/Risk-of-Breast-Cancer-in-Postmenopausal-Women-Increased-by-High-Estrogen-Levels-92418-1.htm http://www.medindia.net/news/Estrogen-Helps-Keep-Weight-in-Check-UT-Southwestern-Study-92331-1.htm The female sex hormone estrogen regulates energy expenditure, appetite and body weight, a recent UT Southwestern Medical Center study has found. It added that insufficient estrogen receptors in specific parts of the brain may lead to obesity. "Estrogen has a profound effect on metabolism," said Dr. Deborah Clegg, associate professor of internal medicine and senior author of the study published Oct. 5 in ICell Metabolism/I. "We hadn't previously thought of sex hormones as being critical regulators of food intake and body weight....]]> http://www.medindia.net/news/Estrogen-Helps-Keep-Weight-in-Check-UT-Southwestern-Study-92331-1.htm http://www.medindia.net/news/Estrogen-may-Prevent-Younger-Menopausal-Women-from-Strokes-91897-1.htm Estrogen may prevent strokes in premature or early menopausal women, Mayo Clinic researchers say. Their findings challenge the conventional wisdom that estrogen is a risk factor for stroke at all ages. The study was published in the journal IMenopause/I. Researchers combined the results from a recent Mayo Clinic study with six other studies from across the world and found that estrogen is protective for stroke before age 50. That is roughly the average age when women go through menopause....]]> http://www.medindia.net/news/Estrogen-may-Prevent-Younger-Menopausal-Women-from-Strokes-91897-1.htm http://www.medindia.net/news/Pregnant-Women-Who-Used-Synthetic-Estrogen-in-1970s-Increased-Infertility-and-Cancer-Risk-in-Their-Daughters-91649-1.htm Daughters of women who took a synthetic estrogen called diethylstilbestrol (DES) while pregnant decades ago are now facing a greater chance of being infertile and developing cancer, according to a large study by the National Cancer Institute in the United States. In 1971, the U.S. Food and Drug Administration said DES should not be given to pregnant women. But by that time, between 5 million and 10 million moms-to-be and their babies had been exposed to the drug. DES was widely used in 1940s ...]]> http://www.medindia.net/news/Pregnant-Women-Who-Used-Synthetic-Estrogen-in-1970s-Increased-Infertility-and-Cancer-Risk-in-Their-Daughters-91649-1.htm http://www.medindia.net/news/Women-at-High-Risk-of-Ovarian-Cancer-Should-Have-Ovaries-Removed-90299-1.htm Women, who are at high risk of developing breast or ovarian cancer, should consider having their ovaries removed as a way to avert the risk. Prof Gareth Evans of Manchester University said that women who carry a family history of ovarian cancer should consider surgical removal of the ovaries to offset the risk of developing tumors. Women who already have children, feel their family is complete and are above 40 years of age should seriously think of having the ovaries removed. This causes early ...]]> http://www.medindia.net/news/Women-at-High-Risk-of-Ovarian-Cancer-Should-Have-Ovaries-Removed-90299-1.htm http://www.medindia.net/news/Metabolic-Syndrome-Atherosclerosis-Linked-to-Loss-of-Key-Estrogen-Regulator-90294-1.htm The loss of a key protein that regulates estrogen and immune activity in the body could lead to aspects of metabolic syndrome, atherosclerosis and cancer, says a UCLA study. Called estrogen receptor alpha, this protein is critical in regulating immune system activity such as helping cells suppress inflammation and gobble-up debris. This early preclinical study in female mice demonstrated that removing estrogen regulator alpha alone was enough to reduce the immune system's protective process ...]]> http://www.medindia.net/news/Metabolic-Syndrome-Atherosclerosis-Linked-to-Loss-of-Key-Estrogen-Regulator-90294-1.htm http://www.medindia.net/news/How-Estrogen-Could-Help-Protect-Women-from-Cardiovascular-Disease-89033-1.htm New research from Queen Mary, University of London has revealed that the sex hormone oestrogen could help protect women from cardiovascular disease by keeping the body's immune system in check. The study has shown that the female sex hormone works on white blood cells to stop them from sticking to the insides of blood vessels, a process which can lead to dangerous blockages. The results could help explain why cardiovascular disease rates tend to be higher in men and why they soar in women after the menopause....]]> http://www.medindia.net/news/How-Estrogen-Could-Help-Protect-Women-from-Cardiovascular-Disease-89033-1.htm http://www.medindia.net/news/Estrogen-Deprivation-Increases-Stroke-Risk-88688-1.htm In aging rats prolonged estrogen deprivation reduces the number of brain receptors and increases the risk of stroke, finds study. However, the damage is forestalled if estrogen replacement begins shortly after hormone levels drop, according to a study. "This is further evidence of a critical window for estrogen therapy, either right before or right after menopause," said Dr. Darrell W. Brann, Chief of GHSU's Developmental Neurobiology Program and the study's corresponding author. The ...]]> http://www.medindia.net/news/Estrogen-Deprivation-Increases-Stroke-Risk-88688-1.htm http://www.medindia.net/news/Study-On-How-Estrogen-Signals-Onset-of-Breast-Cancer-Published-86561-1.htm The first roadmap to mathematical modeling of a powerful basic "decision circuit" in breast cancer has been developed and published in INature Reviews Cancer/I. The preliminary mathematical model is the first result of a (Dollor) 7.5 million federal grant, awarded to scientists at the Lombardi Comprehensive Cancer Center at Georgetown University Medical Center (GUMC) and collaborators at Virginia Tech and Fox Chase Cancer Center, to develop a systems approach to understanding and treating one of the most common forms of breast cancer....]]> http://www.medindia.net/news/Study-On-How-Estrogen-Signals-Onset-of-Breast-Cancer-Published-86561-1.htm http://www.medindia.net/news/Link-Between-Obesity-and-Low-Estrogen-Levels-Identified-86106-1.htm A new molecular agent developed by scientists targets the mechanism of estrogen in the brain to find out the effect of aromatase enzyme on body mass index. Enzyme aromatase is crucial for the production of estrogen in tissues throughout the body, including the brain. According to the World Health Organization, worldwide obesity has more than doubled since 1980. As of 2008, an estimated 1.5 billion adults were overweight, and in 2010 nearly 43 million children under the age of five were overweight....]]> http://www.medindia.net/news/Link-Between-Obesity-and-Low-Estrogen-Levels-Identified-86106-1.htm http://www.medindia.net/news/Significant-Progress-In-the-War-Against-Cancer-of-Breast-and-Ovaries-86081-1.htm Significant progress is being made in the prevention and treatment of ovarian and breast cancer, according to findings discussed at a global oncology conference. "The studies presented at this meeting show impressive progress in disease control and prevention of breast cancer," said Dr. Andrew Seidman, professor of medicine at Cornell University. "Also, two consistent studies demonstrated the benefit of adding bevacizumab (Avastin) to standard chemotherapy for ovarian cancer," he added. ...]]> http://www.medindia.net/news/Significant-Progress-In-the-War-Against-Cancer-of-Breast-and-Ovaries-86081-1.htm http://www.medindia.net/news/New-Study-Reveals-Estrogen-Blocker-Cuts-Breast-Cancer-Risk-by-65-86029-1.htm A new study has revealed that an anti-estrogen drug has shown a "promising" 65-percent reduction of breast cancer risk among post-menopausal women. The research could lead to a breakthrough for women who are at increased risk of developing breast cancer, which strikes some 1.3 million women worldwide each year and leads to the death of 500,000 women annually, said lead study author Paul Goss of Harvard Medical School. "The potential public health impact of these findings is important," Goss ...]]> http://www.medindia.net/news/New-Study-Reveals-Estrogen-Blocker-Cuts-Breast-Cancer-Risk-by-65-86029-1.htm http://www.medindia.net/news/Estrogen-Therapy-Increases-Bone-Mass-in-Anorexic-Girls-86006-1.htm In teenage girls with anorexia nervosa, the low bone density is improved by estrogen therapy. Estrogen is given as a patch or as a low oral dose that is physiological (close to the form or amount of estrogen the body makes naturally). A large proportion of adolescents with this eating disorder have low bone density and therefore are at an increased risk of fractures, said Madhusmita Misra, MD, the study's lead author and an associate professor of pediatrics at Harvard Medical School and Massachusetts General Hospital in Boston....]]> http://www.medindia.net/news/Estrogen-Therapy-Increases-Bone-Mass-in-Anorexic-Girls-86006-1.htm http://www.medindia.net/news/Estrogen-Levels-can-be-Altered-Clinical-Study-83511-1.htm Estrogen levels in women can be modified by consuming femMED supplement - a complete line of natural supplements, suggests clinical study. The researchers tested a nutritional combination of indole-3 carbinol, milk thistle extract, calcium-D-glucarate, Schizandra chinensis fruit extract, stinging nettle, lignans extracted from the Norway spruce, and vitamin D on 47 pre-menopausal women and 49 post-menopausal women for 28 days. On day one and 28, they analyzed blood and urine samples. Researchers ...]]> http://www.medindia.net/news/Estrogen-Levels-can-be-Altered-Clinical-Study-83511-1.htm http://www.medindia.net/news/New-Approach-Shields-Primate-Ovaries-from-Damage-81385-1.htm Researchers have developed a protective strategy that aids in the shielding of female mammals ovaries from damaging effects of radiation and chemotherapy. Reports say that brief preexposure of the ovaries to an FDA-approved agent called FTY720 preserved the fertility of female rhesus monkeys exposed to potentially lethal doses of radiation. All of the treated animals have had successful pregancies and delivered healthy offspring. "When we started working on this project in the mid-1990s, ...]]> http://www.medindia.net/news/New-Approach-Shields-Primate-Ovaries-from-Damage-81385-1.htm http://www.medindia.net/news/How-Progesterone-Prevents-Preterm-Birth-80688-1.htm Three proteins known as XIAP, BID, and Bcl-2 are responsible in part for the success of progesterone treatments in the prevention of preterm labor, according to research presented today at the 31st Annual meeting of the Society for Maternal-Fetal Medicine (SMFM) The Pregnancy Meeting. They may also play an important role in triggering normal labor. The proteins prevent preterm birth by hindering apoptosis - the normal, orderly death of cells -- in the fetal membranes. Stronger, thicker ...]]> http://www.medindia.net/news/How-Progesterone-Prevents-Preterm-Birth-80688-1.htm http://www.medindia.net/news/Progesterone-and-Estrogen-Boost-Breast-Cancer-Risk-79713-1.htm Scientists have discovered how the progesterone and estrogen hormones interact and thereby increases the risk of breast cancer. The hormones increases cell growth in normal mammary cells and mammary cancers. The novel finding may explain why postmenopausal women receiving hormone replacement therapy with estrogen plus progestin are at increased risk of breast cancer. The discovery that both estrogen and progesterone must be present for the increased production of the protein amphiregulin, ...]]> http://www.medindia.net/news/Progesterone-and-Estrogen-Boost-Breast-Cancer-Risk-79713-1.htm http://www.medindia.net/news/Estrogen-Makes-Precancerous-Cells-Deadly-in-the-Oral-Cavity-79003-1.htm Researchers at Fox Chase Cancer Center have found that estrogen may increase the movement of precancerous cells in the mouth and thus promote the spread of the disease within the oral cavity. Margie Clapper, co-leader of the Cancer Prevention and Control Program at Fox Chase Cancer Center and colleagues had previously reported that estrogen metabolism changes following smoke exposure in the lungs and may contribute to lung cancer. To find out if this female hormone ...]]> http://www.medindia.net/news/Estrogen-Makes-Precancerous-Cells-Deadly-in-the-Oral-Cavity-79003-1.htm http://www.medindia.net/news/Estrogen-Reduces-Breast-Cancer-Risk-77813-1.htm In a study it has been pointed out that exogenous estrogen which is used in hormone replacement therapy (HRT) is effective in reducing the risk of breast cancer. However the endogenous estrogen (i.e., estrogen produced by ovaries and by other tissues) is shown to have a carcinogenic impact. The results of this study was presented at the 33rd Annual CTRC-AACR San Antonio Breast Cancer Symposium, held Dec. 8-12. "Our analysis suggests that, contrary to previous thinking, there is substantial ...]]> http://www.medindia.net/news/Estrogen-Reduces-Breast-Cancer-Risk-77813-1.htm http://www.medindia.net/news/The-Value-of-Estrogen-76874-1.htm Estrogen has been found to enhance mental agility and also to have the potential in treating Alzheimer's and schizophrenia. But long-term estrogen therapy, once prescribed routinely for menopausal women, now is quite controversial because of research showing it increases the risk of cancer, heart disease and stroke. Northwestern Medicine researchers have discovered how to reap the benefits of estrogen without the risk. Using a special compound, they flipped a switch that mimics the effect of estrogen on cortical brain cells....]]> http://www.medindia.net/news/The-Value-of-Estrogen-76874-1.htm http://www.medindia.net/news/Noninvasive-Way-To-Determine-Estrogen-Levels-In-Infants-Thanks-To-Diapers-76841-1.htm Emory University researchers in US have developed a noninvasive way to determine estrogen levels in infants by putting under the microscope more than 5000 diapers. The new technique, previously used in nonhuman primates, will allow researchers to learn more about the association between estrogen levels in human infants and their long-term reproductive development as well as the development of sex-specific behaviors, such as toy preference or cognitive differences. What's more, the method will also ...]]> http://www.medindia.net/news/Noninvasive-Way-To-Determine-Estrogen-Levels-In-Infants-Thanks-To-Diapers-76841-1.htm http://www.medindia.net/news/Women-Asked-to-Freeze-Ovaries-in-20s-75954-1.htm Women can increase the chances of giving birth to a child later in their life by freezing some part of their ovaries, one of the world's leading gynecologists said. Dr Sherman Silber, who performed the first whole ovary transplant in 2007, said that such a move would increase the fertility of even a 40-year old and thereby avoiding any problems if couples decide to wait for some time before having children. Dr Silber said that there are procedures through which slivers of ovaries, containing hundreds ...]]> http://www.medindia.net/news/Women-Asked-to-Freeze-Ovaries-in-20s-75954-1.htm http://www.medindia.net/news/Ovarian-Cancer-Growth-Quickens-With-Estrogen-Replacement-Therapy-75643-1.htm A type of ovarian cancer develops five times faster when menopausal women use estrogen therapy, claim researchers at the University of Colorado Cancer Center. Menopausal estrogen replacement therapy (ERT) also significantly increases the likelihood of the cancer metastasizing to the lymph nodes, according to the study, which will be published in the Nov. 1 issue of ICancer Research/I. The study was released online Oct. 19, 2010. ICancer Research,/I published by the American Association ...]]> http://www.medindia.net/news/Ovarian-Cancer-Growth-Quickens-With-Estrogen-Replacement-Therapy-75643-1.htm http://www.medindia.net/news/Estrogen-Therapy-Elevates-Kidney-Stones-Risk-in-Postmenopausal-Women-75272-1.htm A new report has suggested that the use of estrogen therapy is associated with an increased risk of developing kidney stones in postmenopausal women. Using data from the national Women's Health Initiative study, Naim M. Maalouf, of the University of Texas Southwestern Medical Center, Dallas, examined data from two trials: 10,739 postmenopausal women with hysterectomy who received either an estrogen-only treatment or matching placebo and 16,608 postmenopausal women without hysterectomy who received ...]]> http://www.medindia.net/news/Estrogen-Therapy-Elevates-Kidney-Stones-Risk-in-Postmenopausal-Women-75272-1.htm http://www.medindia.net/news/High-Estrogen-Levels-Linked-to-Lack-of-Concentration-in-Women-74480-1.htm High estrogen levels in women while they are ovulating may be directly responsible for sluggishness or problems concentrating, a Canadian study released Friday has found. Researchers at Concordia University's Center for Studies in Behavioral Neurobiology in Montreal linked high estrogen levels in laboratory rats to an inability to pay attention and learn. These high levels have also been shown to interfere with women's ability to pay attention, but the study, to be published in the journal ...]]> http://www.medindia.net/news/High-Estrogen-Levels-Linked-to-Lack-of-Concentration-in-Women-74480-1.htm http://www.medindia.net/news/Exposure-to-Low-Doses-of-Bisphenol-A-Alters-Mice-Ovaries-73272-1.htm A new research showed that exposure to low doses of BPA altered gene expression in the fetal mouse ovary. Bisphenol A (BPA) is a chemical used in plastics for making some baby and water bottles, linings of food and beverage cans, and other human consumer products. The study reported that exposure of pregnant female mice to the endocrine-disrupting chemical bisphenol A may produce adverse reproductive consequences on gene expression in fetal ovaries as early as 12 hours after ...]]> http://www.medindia.net/news/Exposure-to-Low-Doses-of-Bisphenol-A-Alters-Mice-Ovaries-73272-1.htm http://www.medindia.net/news/In-Postmenopausal-Women-Estrogen-Not-Linked-to-Lung-Cancer-Mortality-72708-1.htm Use of estrogen alone did not increase lung cancer mortality in postmenopausal women, a new study has found. In the Women's Health Initiative (WHI) trial, which consisted of several clinical trials on postmenopausal women, one study showed women with previous hysterectomy taking combined estrogen plus progestin therapy had a statistically significant increase in lung cancer mortality, but not incidence. Other studies with combined hormone therapy have had conflicting results. But the influence of estrogen alone was unclear....]]> http://www.medindia.net/news/In-Postmenopausal-Women-Estrogen-Not-Linked-to-Lung-Cancer-Mortality-72708-1.htm http://www.medindia.net/news/Breast-Cancer-Cells-Control-As-Many-as-14-Genes-in-Response-to-Estrogen-71620-1.htm In response to the hormone estrogen, breast cancer cells regulate many genes at once, resulting in the silencing of 14 genes at one time. Researchers at The Ohio State University Comprehensive Cancer Center provides the first evidence that cells can regulate many genes at once by looping their DNA, contributing to cancer when it goes awry. Tim H.M. Huang and Pei-Yin Hsu discovered the DNA looping event in a breast cancer cell line gene cluster at chromosome region 16p11.2. They validated ...]]> http://www.medindia.net/news/Breast-Cancer-Cells-Control-As-Many-as-14-Genes-in-Response-to-Estrogen-71620-1.htm http://www.medindia.net/news/Enjoying-the-Benefits-of-Estrogen-Without-Cancer-Risk-70477-1.htm Scientists have found a way to get the best benefit of estrogen without increasing the risk of cancer. Researchers at UT Southwestern Medical Center have pinpointed a set of biological mechanisms through which estrogen confers its beneficial effects on the cardiovascular system, independent of the hormone's actions on cancer. The study suggests that drugs targeting a specific subpopulation of estrogen receptors found outside the cell nucleus might activate the cardiovascular benefits of estrogen without increasing cancer risk....]]> http://www.medindia.net/news/Enjoying-the-Benefits-of-Estrogen-Without-Cancer-Risk-70477-1.htm http://www.medindia.net/news/Progesterone-A-Better-Treatment-for-Post-menopausal-Symptoms-70404-1.htm Oral micronized progesterone could be another way to treat hot flashes and night sweats endured by post-menopausal women. Available only by prescription and sold under the brand name Prometrium in the United States and Canada, this form of progesterone is manufactured from a steroid in yams. "This is the first evidence that oral micronized progesterone, which is molecularly identical to the natural hormone, is effective for women with symptomatic hot flashes," said the presenting author, Dr....]]> http://www.medindia.net/news/Progesterone-A-Better-Treatment-for-Post-menopausal-Symptoms-70404-1.htm http://www.medindia.net/news/Female-Fertility-Regulated-by-Active-Male-Sex-Hormones-in-Ovaries-69372-1.htm Male sex hormones, such as testosterone, present and active in the ovaries, helps regulate female fertility, probably by controlling follicle growth and development and preventing deterioration of follicles that contain growing eggs, a new study suggests. The study highlights the fact that women need certain levels of male hormones, or androgens, in their bodies to function normally. The current study, published today in the journal Molecular Endocrinology, ...]]> http://www.medindia.net/news/Female-Fertility-Regulated-by-Active-Male-Sex-Hormones-in-Ovaries-69372-1.htm http://www.medindia.net/news/Brain-Estrogen-Drug-may-be-Beneficial-for-Women-Suffering-Schizophrenia-67144-1.htm Raloxifene, a drug presently used to treat osteoporosis, is found to be good for women who suffer from schizophrenia, a recent research has revealed. Raloxifene, which influences neurotransmitter and neuronal systems in the brain, has beneficial effects on postmenopausal women with schizophrenia, with a test group experiencing a more rapid recovery from psychotic and other symptoms compared to control groups. Research project leader and Director of the Monash Alfred ...]]> http://www.medindia.net/news/Brain-Estrogen-Drug-may-be-Beneficial-for-Women-Suffering-Schizophrenia-67144-1.htm http://www.medindia.net/news/Osteoporosis-Due-to-Age-Not-Estrogen-Fall-65754-1.htm Scientists at the University of Arkansas for Medical Sciences (UAMS) have identified an age-related mechanism - not a decrease of the hormone estrogen - as the primary culprit behind osteoporosis. The research team, led by Stavros Manolagas, in the UAMS Center for Osteoporosis and Metabolic Bone Diseases, said that aging and the body's increased inability to defend against bone-damaging molecules produced through a process known as oxidative stress are most directly responsible ...]]> http://www.medindia.net/news/Osteoporosis-Due-to-Age-Not-Estrogen-Fall-65754-1.htm http://www.medindia.net/news/Phase-III-Clinical-Trial-Tests-Progesterone-for-Traumatic-Brain-Injury-65317-1.htm The hormone progesterone will be used by researchers at 17 medical centers across the country to treat patients who experience traumatic brain injury (TBI). The treatment is part of a randomized, double-blind Phase III clinical trial that will enroll approximately 1,140 people over a three- to six-year period beginning in March, 2010. The trial is funded by a grant to Emory University from the National Institutes of Health. The clinical trial is led by David Wright, MD, associate professor ...]]> http://www.medindia.net/news/Phase-III-Clinical-Trial-Tests-Progesterone-for-Traumatic-Brain-Injury-65317-1.htm http://www.medindia.net/news/Estrogen-may-Provide-Protection-Against-Schizophrenia-64068-1.htm Estrogen may help protect women from schizophrenia, a Tel Aviv University study suggests. Published in the journal Psychopharmacology, Prof. Ina Weiner of Tel Aviv University's Department of Psychology and her doctoral student Michal Arad have reported that restoring normal levels of estrogen may work as a protective agent in menopausal women vulnerable to schizophrenia. "We've known for some time that when the level of estrogen is low, vulnerability to psychotic symptoms increases and anti-psychotic drugs are less likely to work....]]> http://www.medindia.net/news/Estrogen-may-Provide-Protection-Against-Schizophrenia-64068-1.htm http://www.medindia.net/news/Progesterone-Could-be-Effective-for-Traumatic-Brain-Injuries-62826-1.htm Researchers at Emory University in Atlanta, GA, suggest the use of progesterone (PROG), a naturally occurring hormone found in both males and females which is capable of protecting damaged cells in the central and peripheral nervous system. This can be considered a viable treatment option for traumatic brain injuries, according to a clinical perspective published in the January issue of the IAmerican Journal of Roentgenology/I. "Traumatic brain injury (TBI) is an important clinical problem ...]]> http://www.medindia.net/news/Progesterone-Could-be-Effective-for-Traumatic-Brain-Injuries-62826-1.htm http://www.medindia.net/news/Progesterone-Injection-Linked-to-Reduction-in-Breast-Cancer-Death-Rates-62313-1.htm A study conducted by the doctors of Tata Memorial Cancer Hospital says that an injection of progesterone can help bring about a 30% reduction in breast cancer death rates. The best part is that this injection costs just Rs 100. Dr Indraneel Mittra of department of surgical oncology detailed the procedure saying that this was a double-blind trial in which half the participating women were given 500 mg injections of progesterone for four to 14 days before surgery. The 1,000 women in the study were followed up for 65 months....]]> http://www.medindia.net/news/Progesterone-Injection-Linked-to-Reduction-in-Breast-Cancer-Death-Rates-62313-1.htm http://www.medindia.net/news/Study-Says-Ovaries-Must-Suppress-Their-Inner-Male-62200-1.htm A study in the December 11th issue of the journal ICell/I, a Cell Press publication says that the ovaries of mice can be reprogrammed into testes by silencing a single gene. The findings may have implications for understanding certain sex disorders in children and premature menopause in women, the researchers say. No one would have previously suspected or believed that an adult organ could be "transdifferentiated" to such an extent by changing a single gene, said Mathias Treier of the ...]]> http://www.medindia.net/news/Study-Says-Ovaries-Must-Suppress-Their-Inner-Male-62200-1.htm http://www.medindia.net/news/The-Positive-Effects-of-Estrogen-as-the-Beneficial-Middleman-for-the-Brain-62127-1.htm Estrogen has been named as the middleman following its beneficial effect on the brain - a finding which raises hopes of developing drugs based on the beneficial action of this hormone. A split-personality chemical, estrogen is thought to protect neural circuits and boost learning and memory, while at the same time increasing cancer risk when taken in high doses. In a new study, neuroscientists at USC and the Western University of Health Sciences show that estrogen sometimes acts through another chemical....]]> http://www.medindia.net/news/The-Positive-Effects-of-Estrogen-as-the-Beneficial-Middleman-for-the-Brain-62127-1.htm