http://www.medindia.net/healthnews/Infantile-Cortical-Hyperostosis-news.asp Medindia largest health website in india. en-us Copyright 2012. All Rights Reserved. Fri, 25 May 2012 06:19:14 GMT http://www.medindia.net/news/bone-disease-incidence-peaks-in-people-with-pulmonary-disease-101609-1.htm An extremely high prevalence of osteopenia/osteoporosis exists among male folks with pulmonary disease, states a new study from researchers in California. "While post-menopausal women are routinely screened for osteoporosis, men are not," said Kathleen Ellstrom, PhD, RN, APRN-BC, Pulmonary Clinical Nurse Specialist and Director of the Pulmonary Rehabilitation Program at the Veterans Administration Loma Linda Healthcare System. "The high prevalence of bone disease we found in male patients referred ...]]> http://www.medindia.net/news/bone-disease-incidence-peaks-in-people-with-pulmonary-disease-101609-1.htm http://www.medindia.net/news/guidance-is-non-specific-but-drugs-reduce-bone-cancer-damage-101413-1.htm A new review finds that bone cancer-related fractures and pain can be reduced by drug treatment, but no one drug is superior. The review is published in The iCochrane Library/i. Researchers undertook a systematic review of the current evidence on bisphosphonate drugs, which are used to prevent bone damage in multiple myeloma. Multiple myeloma is a type of cancer that grows in and on bones, and can cause fractures in long bones and the spine. Severe back pain is a common symptom. Bisphosphonate ...]]> http://www.medindia.net/news/guidance-is-non-specific-but-drugs-reduce-bone-cancer-damage-101413-1.htm http://www.medindia.net/news/commonly-used-chemo-drug-could-aid-the-spread-of-cancer-cells-into-bones-by-fertilizing-bone-marrow-101405-1.htm A new study conducted by researchers at University of Michigan School of Dentistry has found that instead of preventing the spread of cancer, a commonly used chemotherapy drug fertilizes the bone marrow, allowing cancer cells to multiply and spread easily, if it is administered before bone tumors took root. The findings provide valuable insight as to why some cancers metastasize to bone, and could eventually result in new metastasis-prevention drugs, said Laurie McCauley, professor in the Department ...]]> http://www.medindia.net/news/commonly-used-chemo-drug-could-aid-the-spread-of-cancer-cells-into-bones-by-fertilizing-bone-marrow-101405-1.htm http://www.medindia.net/news/scientist-grows-bone-from-human-embryonic-stem-cells-101314-1.htm Scientist on a recent study showed that human embryonic stem cells can be used to grow bone tissue grafts. The study is the first example of using bone cell progenitors derived from human embryonic stem cells to grow compact bone tissue in quantities large enough to repair centimeter-sized defects. When implanted in mice and studied over time, the implanted bone tissue supported blood vessel ingrowth, and continued development of normal bone structure, without demonstrating any incidence of tumor growth....]]> http://www.medindia.net/news/scientist-grows-bone-from-human-embryonic-stem-cells-101314-1.htm http://www.medindia.net/news/study-says-most-senior-citizens-in-delhi-ncr-have-bone-ailments-101154-1.htm A recent study states that as many as 85 percent of senior citizens in the national capital region (NCR) have bone and joint ailments. The epidemiological study by the Arthritis Federation of India (AFI), conducted among 1,300 senior citizens living in residences on the second floor and above, revealed that 10 percent of the elderly in the age group of 60-65 and 17 percent of those above 66 were not able to walk down to the ground floor. Just 56 percent of the people between 60-65 and ...]]> http://www.medindia.net/news/study-says-most-senior-citizens-in-delhi-ncr-have-bone-ailments-101154-1.htm http://www.medindia.net/news/bone-repair-boosted-by-high-strength-silk-scaffolds-100813-1.htm The first all-polymeric bone scaffold material that is wholly biodegradable and able to offer major mechanical support through repair demonstrated by biomedical engineers at Tufts University's School of Engineering. The new technology uses micron-sized silk fibers to reinforce a silk matrix, much as steel rebar reinforces concrete. It could improve the way bones and other tissues are repaired following accident or disease. The discovery is reported in the iProceedings of the National Academy ...]]> http://www.medindia.net/news/bone-repair-boosted-by-high-strength-silk-scaffolds-100813-1.htm http://www.medindia.net/news/soluble-corn-fiber-found-to-improve-bone-health-100568-1.htm A new study presented at the 2012 Experimental Biology conference in San Diego has backed the role of soluble corn fiber in improving bone health. "Years of research point to the health benefits of fiber for cardiovascular health, blood glucose control, digestion and gut health, yet average intake is approximately half the recommended amount," said Joanne Slavin, PhD, RD, of the University of Minnesota and a member of the 2010 Dietary Guidelines Advisory Committee. "With more than 90 percent ...]]> http://www.medindia.net/news/soluble-corn-fiber-found-to-improve-bone-health-100568-1.htm http://www.medindia.net/news/scientists-discover-new-ways-to-treat-brittle-bone-disease-100387-1.htm Scientists have discovered new ways to help detect and treat the debilitating brittle bone disease. According to a scientific study published in the iEuropean Journal of Human Genetics/i, women with a faulty gene have lower bone mass and lose nearly 10 times more bone than women who have a correct copy of a receptor for the energy molecule ATP- (the P2X7 receptor). Osteoporosis is a devastating condition that affects half of all women and a fifth of men over 50 in the UK. The disease ...]]> http://www.medindia.net/news/scientists-discover-new-ways-to-treat-brittle-bone-disease-100387-1.htm http://www.medindia.net/news/diabetic-amputations-may-be-reduced-by-autologous-bone-marrow-derived-mononuclear-cell-transplants-100338-1.htm When transplanted into patients with diabetes who are suffering from critical limb ischemia, autologous mononuclear cells derived from bone marrow (BMMNCs) have been found to significantly induce vascular growth. The team of researchers in Seville, Spain who carried out the study published their results in a recent issue of iCell Transplantation/i (20:10), now freely available on-line at http:www.ingentaconnect.com/content/cog/ct/. "Critical limb ischemia in diabetic patients is associated ...]]> http://www.medindia.net/news/diabetic-amputations-may-be-reduced-by-autologous-bone-marrow-derived-mononuclear-cell-transplants-100338-1.htm http://www.medindia.net/news/animal-mission-in-space-to-boost-bone-protection-in-astronauts-99985-1.htm The longest animal mission in space has concluded and a group of mice involved in the mission are back on Earth. The mission aimed to find a way to prevent breakdown of bones in astronauts. Bone cells either build up bone or break it down depending on their types. Breakdown cells in weight bearing bones become more active in situations like the microgravity experienced in space, when there is no impact on bones. "Astronauts experience around 20 to 30 per cent bone loss," the New Scientist ...]]> http://www.medindia.net/news/animal-mission-in-space-to-boost-bone-protection-in-astronauts-99985-1.htm http://www.medindia.net/news/novel-agent-stops-the-spread-of-deadly-childhood-bone-cancer-99807-1.htm Researchers have discovered an agent that prevents osteosarcoma - bone cancer in children from spreading to the lungs. The new agent stops or inhibits "ezrin," a protein vital to the spread of osteosarcoma, say the researchers who presented their findings today at the American Association for Cancer Research (AACR) Annual Meeting 2012. If proven effective in human studies, their ezrin inhibitor might potentially treat adults whose cancers are fueled by over-expression of this protein, and ...]]> http://www.medindia.net/news/novel-agent-stops-the-spread-of-deadly-childhood-bone-cancer-99807-1.htm http://www.medindia.net/news/bone-size-and-strength-in-childhood-predicted-by-growth-in-the-womb-and-early-infancy-99451-1.htm Early growth predicts the size, mineralization, shape and strength of the hip bone in childhood, say researchers from the MRC Lifecourse Epidemiology Unit, University of Southampton. The presentation was made at the European Congress on Osteoporosis (and) Osteoarthritis (IOF-ECCEO12) which took place in Bordeaux, France from March 21-24, 2012. The study, led by Dr Nicholas Harvey, Senior Lecturer at the MRC LEU, recruited 493 mothers and their offspring from the Southampton Women's Survey, a unique study of mothers and their children....]]> http://www.medindia.net/news/bone-size-and-strength-in-childhood-predicted-by-growth-in-the-womb-and-early-infancy-99451-1.htm http://www.medindia.net/news/treatment-of-heart-failure-with-bone-marrow-cells-probed-by-study-99396-1.htm Using patient's bone marrow cells to treat chronic ischemic heart failure did not result in progress on most measures of heart function, states study appearing in IJAMA/I. The study is being published early online to coincide with its presentation at the American College of Cardiology's annual scientific sessions. Cell therapy has emerged as an innovative approach for treating patients with advanced ischemic heart disease, including those with heart failure. "In patients with ischemic heart ...]]> http://www.medindia.net/news/treatment-of-heart-failure-with-bone-marrow-cells-probed-by-study-99396-1.htm http://www.medindia.net/news/combination-treatment-improves-bone-health-in-post-menopausal-women-99310-1.htm In post-menopausal women with advanced breast cancer, combination of two cancer drugs - everolimus and exemestane improves bone strength, shows study. Professor Michael Gnant told the eighth European Breast Cancer Conference (EBCC-8) today that the latest results from the BOLERO-2 trial would change clinical practice. "These results indicate a new standard of care for women with advanced oestrogen receptor positive breast cancer that is resistant to hormonal therapy," he said. BOLERO-2 ...]]> http://www.medindia.net/news/combination-treatment-improves-bone-health-in-post-menopausal-women-99310-1.htm http://www.medindia.net/news/protective-effect-on-endometrial-cancer-could-be-provided-by-low-bone-density-medications-study-99298-1.htm A protective effect for endometrial cancer could be offered by low bone density medications, such as Fosamax, Boniva and Actonel, states study at Henry Ford Hospital. Endometrial cancer affects more than 45,000 women a year in the U.S., usually in their 60s, although it can occur before 40. A type of uterine cancer, it's the most commonly diagnosed gynecologic cancer, and there is no known preventive medication for women at high risk of developing it. "The results of the study suggest that ...]]> http://www.medindia.net/news/protective-effect-on-endometrial-cancer-could-be-provided-by-low-bone-density-medications-study-99298-1.htm http://www.medindia.net/news/symptoms-of-rett-syndrome-in-mice-halted-by-bone-marrow-transplant-99170-1.htm A new study has revealed that using bone marrow transplant (BMT) to replace faulty immune system cells in mouse models of Rett Syndrome arrested many severe symptoms of the childhood disorder. The latter included abnormal breathing and movement, and significantly extended the rodents' lifespan. Exploring the function of microglia deficient in methyl-CpG binding protein 2 (Mecp2), the protein encoded by the "Rett gene," principal investigator Jonathan Kipnis, Ph.D. and his team at the University ...]]> http://www.medindia.net/news/symptoms-of-rett-syndrome-in-mice-halted-by-bone-marrow-transplant-99170-1.htm http://www.medindia.net/news/new-insights-into-autism-found-via-research-on-rare-bone-disorder-98772-1.htm Multiple hereditary exostoses (MHE) is an inherited genetic disease that affects children, who suffer from multiple growths on their bones that cause pain and disfigurement. But beyond the physical symptoms of this condition, some parents have long observed that their children with MHE also experience autism-like social problems. Buoyed by the support of these parents, researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) used a mouse model of MHE to investigate cognitive function....]]> http://www.medindia.net/news/new-insights-into-autism-found-via-research-on-rare-bone-disorder-98772-1.htm http://www.medindia.net/news/how-resveratrol-intervention-affects-bone-status-98750-1.htm In a recent study scientists looked at the role of resveratrol intervention on bone status. Although many current studies focused on catch up growth (CUG) have described its high susceptibility to insulin resistance-related diseases very few have focused on the effect of CUG on bone metabolism, especially in adulthood. As diet is a controllable factor, the influence of re-feeding with different dietary patterns on bone parameters is important to study. Resveratrol has been attributed a number ...]]> http://www.medindia.net/news/how-resveratrol-intervention-affects-bone-status-98750-1.htm http://www.medindia.net/news/diet-impacting-bone-status-during-catch-up-growth-explained-98584-1.htm Researchers have clarified with diverse diets on bone status and the role of resveratrol in CUG models. Although many current studies focused on catch up growth (CUG) have described its high susceptibility to insulin resistance-related diseases very few have focused on the effect of CUG on bone metabolism, especially in adulthood. As diet is a controllable factor, the influence of re-feeding with different dietary patterns on bone parameters is important to study. Resveratrol has been ...]]> http://www.medindia.net/news/diet-impacting-bone-status-during-catch-up-growth-explained-98584-1.htm http://www.medindia.net/news/promising-treatment-for-life-threatening-bone-disorder-98524-1.htm A new and promising treatment for a rare and life-threatening bone disorder that affects kids has been identified by Washington University School of Medicine researchers. Known as hypophosphatasia, the condition upsets bone metabolism, blocking important minerals such as calcium from depositing in the skeleton. In the March 8, 2012, issue of the INew England Journal of Medicine/I, researchers report that at one year of treatment with a new compound, young patients with the most ...]]> http://www.medindia.net/news/promising-treatment-for-life-threatening-bone-disorder-98524-1.htm http://www.medindia.net/news/taking-vitamin-e-supplements-may-harm-bone-health-98408-1.htm A new study published in the journal Nature Medicine warns that taking vitamin E supplements may cause more harm than good since it encourages the generation of bone degrading cells. Vitamin E is one of the most common forms of vitamins with millions of people across the globe including the supplements in their diet. While vitamin E is a powerful antioxidant thought to reduce the risk of heart disease and cancer, researchers from Keio University in Tokyo found that it also led to thinning of ...]]> http://www.medindia.net/news/taking-vitamin-e-supplements-may-harm-bone-health-98408-1.htm http://www.medindia.net/news/frequent-bone-density-testing-for-women-at-osteoporosis-risk-urged-98313-1.htm Experts have stressed the need for frequent bone density testing for women, who are more at risk of osteoporosis, urging them to avoid lengthy intervals between the tests. Although a recent study suggests that women with normal results on dual-energy X-ray absorptiometry (DXA) scans at ages 67 and older may wait up to 15 years for a second test, a Viewpoint article published today in the IJournal of Bone and Mineral Research/I (JBMR) cautions that such a lengthy interval is inappropriate for many adults....]]> http://www.medindia.net/news/frequent-bone-density-testing-for-women-at-osteoporosis-risk-urged-98313-1.htm http://www.medindia.net/news/stress-slows-loss-of-bone-density-in-sci-patients-97734-1.htm In patients with spinal cord injury (SCI), high doses of stress or load to bone significantly slows the loss of bone density, reveals study. The focus on quantifying the effective dose of load is one of the study's most important aspects, says Richard Shields, P.T., Ph.D., a professor and director of the UI Physical Therapy and Rehabilitation Science Graduate Programs. The study also is the first to carefully test the impact of different doses of load in humans with paralysis. Previous ...]]> http://www.medindia.net/news/stress-slows-loss-of-bone-density-in-sci-patients-97734-1.htm http://www.medindia.net/news/bone-may-be-regenerated-by-cartilage-graft-97666-1.htm New research indicates that painful fractures and bad bone grafts may soon become a thing of the past, thanks to cartilage grafts. "Cartilage graft induces bone that actually integrates with the host bone and vascularizes it (forming blood vessels)," said Ralph S. Marcucio, associate professor of orthopaedics at the University of California San Francisco School of Medicine. Cartilage graft is very different than the current methods used for bone grafting --autograft bone (a person's own bone) or allograft materials (donor bone)....]]> http://www.medindia.net/news/bone-may-be-regenerated-by-cartilage-graft-97666-1.htm http://www.medindia.net/news/broken-bones-may-be-fixed-in-less-than-4-weeks-by-fracture-putty-97368-1.htm A revolutionary 'putty' that can heal bone fractures in days rather than months has been developed by scientists. The University of Georgia Regenerative Bioscience Center scientists used adult stem cells to produce a protein involved in bone healing and generation. They then incorporated them into a gel, combining the healing properties into something they labelled 'fracture putty.' Working with Dr John Peroni from the UGA College of Veterinary Medicine the team used a stabilising device and inserted putty into fractures in rats....]]> http://www.medindia.net/news/broken-bones-may-be-fixed-in-less-than-4-weeks-by-fracture-putty-97368-1.htm http://www.medindia.net/news/researchers-formulate-mode-of-directing-stem-cells-to-boost-bone-formation-and-bone-strength-97231-1.htm UC Davis Health System scientists led research team has built a novel technique to enhance bone growth by using a molecule. When it is injected into the bloodstream, it directs the body's stem cells to travel to the surface of bones. Once these cells are guided to the bone surface by this molecule, the stem cells differentiate into bone-forming cells and synthesize proteins to enhance bone growth. The study, which was published online today in INature Medicine/I, used a mouse model of osteoporosis ...]]> http://www.medindia.net/news/researchers-formulate-mode-of-directing-stem-cells-to-boost-bone-formation-and-bone-strength-97231-1.htm http://www.medindia.net/news/anti-cancer-drug-causes-bone-loss-97158-1.htm A drug commonly used to prevent breast cancer in post-menopausal women weakens bone density thus increasing fracture risk, reveals study. Exemestane -- brand name Aromasin -- is part of a drug class called aromatase inhibitors, which lower levels of the oestrogen that some breast cancers need in order to grow. Canadian bone specialists took a look at a group of patients who had taken part in a study into the effectiveness of exemestane among 4,500 healthy women with a worrying family history of breast cancer....]]> http://www.medindia.net/news/anti-cancer-drug-causes-bone-loss-97158-1.htm http://www.medindia.net/news/growth-in-early-life-may-well-forecast-adult-bone-health-points-delhi-study-97019-1.htm Development in early childhood can influence bone density in adult life, according to New Delhi Birth Cohort study. The data showed that greater height and body massindex (BMI) gain in utero and infancy are associated with higher peak bone mass, and greater BMI gain in childhood/adolescence with higher peak bone density. These associations are mediated by attained adult height and BMI. The study participants comprised 565 men and women aged 33-39 years from the New Delhi Birth Cohort, ...]]> http://www.medindia.net/news/growth-in-early-life-may-well-forecast-adult-bone-health-points-delhi-study-97019-1.htm http://www.medindia.net/news/Study-Reveals-Older-Women-With-Normal-T-Scores-May-Not-Need-Bone-Mineral-Density-Screening-96405-1.htm Women aged 65 and older are routinely screened for osteoporosis using bone mineral density (BMD) screening following recommendations from the U.S. Preventive Services Task Force and other organizations. However, how often women should be screened is a topic that remains controversial and undecided, with no definitive scientific evidence to provide guidance. Now a new study led by Margaret L. Gourlay, MD, MPH of the University of North Carolina at Chapel Hill School of Medicine finds that ...]]> http://www.medindia.net/news/Study-Reveals-Older-Women-With-Normal-T-Scores-May-Not-Need-Bone-Mineral-Density-Screening-96405-1.htm http://www.medindia.net/news/Bone-Marrow-derived-Cells-Source-for-Transplantation-95329-1.htm Bone marrow-derived stem cells have been recognized as a source for transplantation because of its contribution to different cell populations in a variety of organs under normal and diseased conditions. Many BMDC studies have been aimed at repairing damaged brain tissue or helping to restore lost neural function, with much research focused on BMDC transplants to the cerebellum at the back of the brain. In a recent study, a research team from Spain has found that BMDCs, can contribute to ...]]> http://www.medindia.net/news/Bone-Marrow-derived-Cells-Source-for-Transplantation-95329-1.htm http://www.medindia.net/news/Bone-Drugs-Might-Extend-Life-Of-Replacement-Joints-94645-1.htm By means of bone-strengthening drugs the longevity of joint replacements may be prolonged and failure rate could be slashed by half, suggests a new study. Researchers analysed data from patients who were taking bisphosphonates, which are used to prevent the loss of bone material. They looked at data from General Practice Research Database for joint replacements and compared what happened to 1,912 patients taking bisphosphonates with 41,995 patients who did not. After five years, 1.96 ...]]> http://www.medindia.net/news/Bone-Drugs-Might-Extend-Life-Of-Replacement-Joints-94645-1.htm http://www.medindia.net/news/Bone-Thinning-and-Arthritis-Linked-to-Ovary-Removal-in-Younger-Women-94632-1.htm A new study by has found that the removal of Ovary, known as oophorectomy, in women before the age 45 is strongly linked with low-bone mineral density and arthritis in later years. "This is one of the largest national studies, to my knowledge, that highlights the difference in bone-mineral density in women who have their ovaries removed at a young age. Our results suggest that such women should be monitored closely for osteoporosis," says Kala Visvanathan, M.D., M.H.S., associate professor ...]]> http://www.medindia.net/news/Bone-Thinning-and-Arthritis-Linked-to-Ovary-Removal-in-Younger-Women-94632-1.htm http://www.medindia.net/news/Common-Bone-Drug-may-Increase-Life-of-Replacement-Joints-94446-1.htm People who take bisphosphonates, a common bone drug, after joint replacement surgery are less likely to need a repeat operation, finds a new study published on bmj.com today. While hip and knee replacements are cost effective procedures, substantial numbers of patients require revision surgery within 10 years to replace the implant because of infection, wear, loosening, or other mechanical failures. Oral bisphosphonates are used to prevent fractures and to treat common bone diseases like osteoporosis....]]> http://www.medindia.net/news/Common-Bone-Drug-may-Increase-Life-of-Replacement-Joints-94446-1.htm http://www.medindia.net/news/Court-Permits-Payment-for-Bone-Marrow-Donors-94364-1.htm ...]]> http://www.medindia.net/news/Court-Permits-Payment-for-Bone-Marrow-Donors-94364-1.htm http://www.medindia.net/news/Scientists-Discover-Heart-Stem-Cells-That-Make-Muscle-and-Bone-94302-1.htm A new and relatively abundant pool of stem cells in the heart has been identified by researchers. The findings in the December issue of ICell Stem Cell/I, a Cell Press publication, show that these heart cells have the capacity for long-term expansion and can form a variety of cell types, including muscle, bone, neural and heart cells. The researchers say the discovery may lay a foundation for much needed regenerative therapies aimed to enhance tissue repair in the heart. The damaged ...]]> http://www.medindia.net/news/Scientists-Discover-Heart-Stem-Cells-That-Make-Muscle-and-Bone-94302-1.htm http://www.medindia.net/news/Low-Cal-Diet-Rich-in-Proteins-Helps-Obese-Women-Maintain-Bone-Health-94223-1.htm A recent study conducted by researchers at McMaster University suggests that a low calorie diet that is rich in proteins but low on carbohydrates is most effective in improving the bone health of overweight and obese young women when combined with physical exercise. The researchers conducted the test on three different groups of obese and overweight women who were given low, medium or high amounts of dairy foods coupled with higher or lower amounts of protein and carbohydrates over a period of 16 weeks....]]> http://www.medindia.net/news/Low-Cal-Diet-Rich-in-Proteins-Helps-Obese-Women-Maintain-Bone-Health-94223-1.htm http://www.medindia.net/news/3D-Printer-to-Scan-Broken-Bones-94179-1.htm Researchers at Washington State University have developed a 3D printer that can be used to scan broken bones and create "bone-like material" which can be fitted to the damaged bone. The researchers said that this material can act as a scaffold for new bone cells to grow and once the bone repairs itself, the material will dissolve away without any ill effects. According to the report published in the journal Dental Materials, the researchers revealed that they have already tested the material successfully in rats and rabbits....]]> http://www.medindia.net/news/3D-Printer-to-Scan-Broken-Bones-94179-1.htm http://www.medindia.net/news/Growth-Hormone-Replacement-Therapy-for-Obesity-Related-Bone-Loss-94153-1.htm 6-months of growth hormone replacement therapy increased bone formation, bone marrow fat and muscle mass, vitamin D level, thigh muscle mass while led to decrease in the abdominal fat in women with abdominal obesity, according to a study by the University of Alabama at Birmingham.Due to obesity the growth hormone level in the body is reduced. This lower level of growth hormones makes obese women more prone to osteoporosis.When scientists subjected about 79 women to growth hormone replacement therapy ...]]> http://www.medindia.net/news/Growth-Hormone-Replacement-Therapy-for-Obesity-Related-Bone-Loss-94153-1.htm http://www.medindia.net/news/Genetic-Predisposition-to-Bone-Cancer-94088-1.htm Genes may increase the risk of developing bone marrow cancer by 30%, according to researchers at UK's Institute of Cancer Research (ICR). Previously it was known that relatives of people with multiple myeloma have a twofold to fourfold increased risk of suffering the disease themselves, but until now, no responsible gene had been identified.Scientists scanned the DNA of 1,675 patients with multiple myeloma and compared them to the genes of around 5,900 healthy people. They found two genetic variants ...]]> http://www.medindia.net/news/Genetic-Predisposition-to-Bone-Cancer-94088-1.htm http://www.medindia.net/news/Drug-Delays-Onset-of-Bone-Metastasis-in-Prostate-Cancer-93510-1.htm In men with prostate cancer, denosumab - a monoclonal antibody suppresses the normal breakdown of bone and thereby delays the development of bone metastases, shows study published in The ILancet/I. "Prostate cancer patients who develop bone metastases usually have poor outcomes, so preventing the development of metastasis has been a major unmet clinical need," says Matthew Smith, MD, PhD, of the MGH Cancer Center, lead and corresponding author of the ILancet/I paper. "This first ...]]> http://www.medindia.net/news/Drug-Delays-Onset-of-Bone-Metastasis-in-Prostate-Cancer-93510-1.htm http://www.medindia.net/news/Dairy-Diet-may-Improve-Bone-Health-in-Obese-Premenopausal-Women-93249-1.htm When diary foods and higher protein are consumed, it might improve bone health during diet and exercise in premenopausal women who are overweight, study has suggested. Stuart Phillips and his team from the McMaster University in Hamilton, Ontario conducted a controlled randomised weight loss intervention trial involving 90 premenopausal overweight or obese women which was designed to achieve weight loss and be supportive of bone health. They employed modest dietary calorie restriction and ...]]> http://www.medindia.net/news/Dairy-Diet-may-Improve-Bone-Health-in-Obese-Premenopausal-Women-93249-1.htm http://www.medindia.net/news/Wine-can-Uplift-Your-Spirit-Right-Till-Your-Bones-92258-1.htm STRONGMany wine lovers will just love to hear this, a recent study has revealed that wine can actually strengthen the bones and reduce the risk of osteoporosis. /STRONGSTRONG/STRONGSTRONGA study of post menopausal twins, which delved into the link between nutrition and diet and its connection with osteoporosis, found that wine drinkers had a higher bone density in the spine and hip as compared to non-drinkers./STRONG STRONG/STRONG STRONGThe benefits seemed much more than the gains ...]]> http://www.medindia.net/news/Wine-can-Uplift-Your-Spirit-Right-Till-Your-Bones-92258-1.htm http://www.medindia.net/news/Bone-Drug-Maintains-Bone-Health-in-Breast-Cancer-Patients-91758-1.htm Zoledronic acid drug protects against the bone damaging side effects of certain breast cancer medications, reveals study published early online in ICancer/I, a peer-reviewed journal of the American Cancer Society. Drugs called aromatase inhibitors stop the production of estrogen in postmenopausal women and therefore make less estrogen available to stimulate the growth of certain breast cancer cells. Many postmenopausal women with breast cancer are routinely treated for several years with ...]]> http://www.medindia.net/news/Bone-Drug-Maintains-Bone-Health-in-Breast-Cancer-Patients-91758-1.htm http://www.medindia.net/news/Gene-That-Modulates-Bone-Mass-Identified-91583-1.htm Institut de recherches cliniques de Montr'al (IRCM) researchers have identified a novel gene that modulates bone mass, this gene could become a risk factor for developing osteoporosis. This scientific breakthrough published in the scientific journal ICell Metabolism/I. Osteoporosis is a "silent" genetic disease characterized by low bone mineral density and deterioration of bone tissue, which leads to increased bone fragility and risk of fracture. In all cases, the disease is caused by an ...]]> http://www.medindia.net/news/Gene-That-Modulates-Bone-Mass-Identified-91583-1.htm http://www.medindia.net/news/Bone-Growth-from-Implanted-Tooth-and-Dental-Pulp-Stem-Cells-Proved-Through-Cell-Transplantation-91188-1.htm Researchers in Japan have completed a study showing that stem cells derived from deciduous canine teeth and dental pulp can be grafted and produce bone regeneration between parents and offspring. Their results are published in the current issue of A HREF="http:www.ingentaconnect.com/content/cog/ct/"ICell Transplantation/I/A (20:7), now freely available on-line. "Bone defects can occur for a number of reasons, and autogenous bone grafting - using the patient's own bone - has been a ...]]> http://www.medindia.net/news/Bone-Growth-from-Implanted-Tooth-and-Dental-Pulp-Stem-Cells-Proved-Through-Cell-Transplantation-91188-1.htm http://www.medindia.net/news/Bone-Drug-Reduces-Breast-Cancer-Recurrence-91160-1.htm Use of zoledronic acid found to reduce the recurrence of breast cancer in post-menopausal women, shows study. Researchers think it could be the key for a greater understanding of the mechanisms of breast cancer recurrence as well as offering new options for patient care. Zoledronic acid is one of the bisphosphonates, a group of drugs mainly used to treat osteoporosis. However they are also given to cancer patients to protect against the effects of secondary bone cancer, such as pain and weakness in the bones....]]> http://www.medindia.net/news/Bone-Drug-Reduces-Breast-Cancer-Recurrence-91160-1.htm http://www.medindia.net/news/Amgens-Prolia-Approved-to-Treat-Bone-Loss-in-Prostate-and-Breast-Cancer-Patients-90834-1.htm The market for Amgen Inc's Prolia has been expanded for two new uses after the US Food and Drug Administration approved the osteoporosis drug to be used for treating bone loss among patients with breast cancer and non-metastatic prostate cancer. The drug was initially approved by the FDA last year to treat osteoporosis among post-menopausal women. In July 2010 the FDA gave a priority review for Prolia with regard to its ability to reduce skeletal-related events in cancer patients with bone metastases....]]> http://www.medindia.net/news/Amgens-Prolia-Approved-to-Treat-Bone-Loss-in-Prostate-and-Breast-Cancer-Patients-90834-1.htm http://www.medindia.net/news/Thyroid-stimulating-Hormone-Directly-Influences-Bone-Growth-Study-90545-1.htm Building hope for future bone damage treatments, researchers at Mount Sinai School of Medicine have found that thyroid-stimulating hormone (TSH), a hormone produced in the anterior pituitary gland that regulates endocrine function in the thyroid gland, can promote bone growth independent of its usual thyroid functions. The research suggests that TSH, or drugs that mimic its affect on bone, may be key to possible future treatments for osteoporosis and other conditions involving bone loss, such as cancer....]]> http://www.medindia.net/news/Thyroid-stimulating-Hormone-Directly-Influences-Bone-Growth-Study-90545-1.htm http://www.medindia.net/news/Half-Match-Bone-Marrow-Transplant-Procedure-Shows-Promising-Results-90151-1.htm A clinical trial conducted at the Kimmel Cancer Center at Jefferson testing its unique, two-step half-match procedure has produced some promising results. The probability of overall survival was 45 percent in all patients after three years and 75 percent in patients who were in remission at the time of the transplant. Neal Flomenberg, M.D., Chair of the Department of Medical Oncology at Thomas Jefferson University Hospital, Dolores Grosso, DNP, Co-Principal Investigator and lead author of ...]]> http://www.medindia.net/news/Half-Match-Bone-Marrow-Transplant-Procedure-Shows-Promising-Results-90151-1.htm http://www.medindia.net/news/Acute-Stroke-can-be-Safely-Treated-by-Patients-Own-Bone-Marrow-Stem-Cells-90080-1.htm Using a patient's own bone marrow stem cells to treat acute stroke is feasible and safe, results of a groundbreaking Phase I trial at the University of Texas Health Science Center at Houston (UTHealth) have indicated. The trial was the first ever to harvest an acute stroke patient's own stem cells from the iliac crest of the leg, separate them and inject them back into the patient intravenously. The first patient was enrolled in March 2009 at Memorial Hermann-Texas Medical Center. "In ...]]> http://www.medindia.net/news/Acute-Stroke-can-be-Safely-Treated-by-Patients-Own-Bone-Marrow-Stem-Cells-90080-1.htm