http://www.medindia.net/healthnews/Gout-news.asp Medindia largest health website in india. en-us Copyright 2012. All Rights Reserved. Fri, 25 May 2012 05:49:22 GMT http://www.medindia.net/news/antihypertensive-drugs-and-risk-of-incident-gout-among-patients-with-hypertension-99121-1.htm Hypertension is one of the most common comorbidities of gout. Studies have shown that the presence of hypertension is independently associated with the risk of incident gout through reduced renal blood flow with increased renal and systemic vascular resistance and decreased renal excretion of urate. bHypertension/b is the term used to describe high blood pressure. Blood pressure is a measurement of the force against the walls of your arteries as your heart pumps blood through your body....]]> http://www.medindia.net/news/antihypertensive-drugs-and-risk-of-incident-gout-among-patients-with-hypertension-99121-1.htm http://www.medindia.net/news/antihypertensive-medications-associated-with-gout-97516-1.htm bBlood pressure-lowering medications like calcium channel blockers and losartan may protect against gout in people with hypertension, according to a recent study./b Gout is a condition where uric acid levels in the blood rise, either due to increased production of uric acid by the body or decreased excretion in the urine. It causes joint inflammation, especially of the big toe, resulting in a painful, swollen and red toe. Other joints like the knee and ankle may also be affected....]]> http://www.medindia.net/news/antihypertensive-medications-associated-with-gout-97516-1.htm http://www.medindia.net/news/Skimmed-Milk-may-Help-Cut-Gout-Flares-96509-1.htm Skimmed milk enriched with two components of dairy products may help reduce the frequency of gout flare-ups, shows research. Previous long term research has shown that the risk of gout is greater among those whose diet is low on dairy products. And experimental studies indicate that certain components of dairy products, particularly glycomacropeptide (GMP) and G600 milk fat extract (G600), seem to dampen down the inflammatory response to gout crystals. The authors studied the ...]]> http://www.medindia.net/news/Skimmed-Milk-may-Help-Cut-Gout-Flares-96509-1.htm http://www.medindia.net/news/Clinical-Trial-Result-Rilonacept-Significantly-Reduces-Gout-Flares-95738-1.htm Rilonacept, an inhibitor of the protein interleukin-1 (IL-1), significantly reduced acute gout flares that occur when initiating uric acid-lowering therapy, a phase II clinical trial found. Results of the trial-the first placebo-controlled study investigating IL-1 targeted therapy in prevention of gout flares-show rilonacept to be generally well tolerated with no serious infections or treatment-related serious adverse events reported. Full findings are published in iArthritis (and) Rheumatism/i, ...]]> http://www.medindia.net/news/Clinical-Trial-Result-Rilonacept-Significantly-Reduces-Gout-Flares-95738-1.htm http://www.medindia.net/news/CT-Scans-can-Help-Detect-Gout-93034-1.htm Computerized tomography scanning (CT scan) appears to help in the diagnosis of gout. The type of CT scan analyzed, dual-energy computed tomography, is also valuable for diagnosing people who cannot be tested with the typical method of drawing fluid from joints, researchers found. The study is being presented at the American College of Rheumatology/A annual scientific meeting in Chicago. The buildup of uric acid crystals in and around joints, causing inflammation and painful, potentially ...]]> http://www.medindia.net/news/CT-Scans-can-Help-Detect-Gout-93034-1.htm http://www.medindia.net/news/Poor-Footwear-Choices-Increase-Foot-Impairment-and-Disability-in-Gout-Patients-91547-1.htm Gout patients who make poor footwear choices experience higher foot-related pain, impairment and disability, a new study found. New research shows that use of poor footwear is common among patients with gout. According to the study published today in Arthritis Care (and) Research, a peer-reviewed journal of the American College of Rheumatology (ACR) gout patients also reported that comfort, fit, support and cost were the most important factors for selecting footwear. Gout is a type of inflammatory ...]]> http://www.medindia.net/news/Poor-Footwear-Choices-Increase-Foot-Impairment-and-Disability-in-Gout-Patients-91547-1.htm http://www.medindia.net/news/New-Gout-Drug-Proves-Effective-89261-1.htm Patients with chronic gout who received the medication pegloticase showed greater improvement in uric acid measures as well as physical function and quality of life, shows study. Long-term urate (a salt derived from uric acid) lowering therapy in gout aims to maintain concentrations of uric acid (UA) below a certain level. However, it is common for UA levels to exceed a recommended goal urate range during oral urate-lowering therapy among the 5 to 6 million U.S. patients with gout, according to background information in the article....]]> http://www.medindia.net/news/New-Gout-Drug-Proves-Effective-89261-1.htm http://www.medindia.net/news/Surge-in-Prevalence-of-Gout-in-US-Over-Last-Two-Decades-88391-1.htm The prevalence of gout among the Americans has risen over the last two decades with 8.3 million of the population suffering from it. Prevalence of increased uric acid levels (hyperuricemia) also rose, affecting 43.3 million (21%) adults in the U.S. Greater frequency of obesity and hypertension may be associated with the jump in prevalence rates according to the findings now available in IArthritis (and) Rheumatism/I, a journal published by Wiley-Blackwell on behalf of the American College of Rheumatology (ACR)....]]> http://www.medindia.net/news/Surge-in-Prevalence-of-Gout-in-US-Over-Last-Two-Decades-88391-1.htm http://www.medindia.net/news/Gout-Drug-Rejected-by-FDA-Panel-86786-1.htm A US Food and Drug Administration panel almost unanimously voted down the recommendation for approving a gout drug developed by Novartis over fears of safety and side effects. The drug was voted down 11-1 by the FDA panel for its usage in preventing gout attacks and also rejected it for using it to delay or reduce the frequency of future attacks. While the drug, known as Ilaris, proved itself to be effective among gout patients, the panel was concerned about the high incidence of infections and side effects....]]> http://www.medindia.net/news/Gout-Drug-Rejected-by-FDA-Panel-86786-1.htm http://www.medindia.net/news/Dual-Energy-CT-Can-Help-Diagnose-The-Severity-Of-Gout-84411-1.htm Duel energy CT has the potential to allow non-invasive diagnosis of gout, according to radiologists at the University of British Columbia. Gout is caused by the deposition of monosodium urate (MSU) monohydrate crystals that stimulate acute episodes of inflammation. Chronic tophaceous gout often presents as juxtarticular soft-tissue masses, distinct erosions, overhanging bony margins, and thickening of the synovium. Gout affects more than six million people in the U.S., and "a non-invasive ...]]> http://www.medindia.net/news/Dual-Energy-CT-Can-Help-Diagnose-The-Severity-Of-Gout-84411-1.htm http://www.medindia.net/news/Risk-of-Gout-in-Women-Increased-by-Fructose-rich-Beverages-76560-1.htm New research has indicated that consumption of fructose-rich beverages, such as sugar-sweetened sodas and orange juice is associated with an increased risk of gout among women. However their contribution to the risk of gout in the population is likely modest because of the low incidence rate among women, according to a study that will appear in the November 24 print edition of IJAMA/I. The study is being released early online to coincide with its presentation at the American College of Rheumatology annual scientific meeting....]]> http://www.medindia.net/news/Risk-of-Gout-in-Women-Increased-by-Fructose-rich-Beverages-76560-1.htm http://www.medindia.net/news/Caffeinated-Drinks-Increase-Risk-Of-Recurrent-Gout-Attacks-76494-1.htm People who drink caffeinated drinks are at an increased risk of recurrent gout attacks, suggests a new study. Long-term caffeine intake has been associated with a decreased risk for gout attacks. However, in the short-term, caffeine has been found to increase uric acid, which can potentially trigger an attack. In a study, researchers studied 633 participants who had experienced a gout attack within one year of the study to compare the amount of caffeinated beverage consumption during ...]]> http://www.medindia.net/news/Caffeinated-Drinks-Increase-Risk-Of-Recurrent-Gout-Attacks-76494-1.htm http://www.medindia.net/news/Gout-Patients-Find-Urate-Lowering-Therapy-Beneficial-76467-1.htm Patients with gout would find urate lowering therapy beneficial since it could prevent death from cardiovascular disease, states research presented in Atlanta. The research presented at the American College of Rheumatology Annual Scientific Meeting brought out that hyperuricemia is an abnormally high level of uric acid in the blood that can lead to gout - a painful and potentially disabling form of arthritis that has been recognized since ancient times. Initial symptoms of gout usually consist ...]]> http://www.medindia.net/news/Gout-Patients-Find-Urate-Lowering-Therapy-Beneficial-76467-1.htm http://www.medindia.net/news/Sugar-sweetened-Soft-Drinks-Raise-Gout-Risk-in-Women-76403-1.htm A study has revealed that sweetened drinks can increase the risk of gout in women. Women who consume fructose-rich beverages, such as sugar-sweetened soft drinks and orange juice, are at an increased risk for gout, according to research by University of British Columbia. Gout is a painful and potentially disabling form of arthritis, which manifests itself in the form of intense episodes of painful swelling in single joints, most often in the feet. Gout occurs ...]]> http://www.medindia.net/news/Sugar-sweetened-Soft-Drinks-Raise-Gout-Risk-in-Women-76403-1.htm http://www.medindia.net/news/Four-Cups-of-Coffee-a-Day-Keeps-Gout-at-Bay-73902-1.htm All it takes for women to more than halve their risk of gout is, a new research reveals, to down four cups of coffee a day. Researchers found that women who drink that amount or more were 57 per cent less likely to suffer from a gout attack than those who drank none. Two to four cups lowered the chances of gout by about 22 per cent but one a day only by three per cent. Researchers from Boston University and Harvard Medical School conducted a long-term study of almost 90,000 female nurses in the U....]]> http://www.medindia.net/news/Four-Cups-of-Coffee-a-Day-Keeps-Gout-at-Bay-73902-1.htm http://www.medindia.net/news/Gout-Drug-Shows-Promise-72130-1.htm BCX4208, a new gout drug, is showing promise. BioCryst Pharmaceuticals Inc, US, developing the drug, reported significant reductions in uric acid blood levels. It also said there were no major safety issues on completion of the first phase of the study it was conducting. The drug was discovered in a collaboration between Industrial Research Limited STRONG(/STRONGIRL) and Professor Vern Schramm, Ruth Merns Chair of Biochemistry at the Albert Einstein College of Medicine, New York.A severe and ...]]> http://www.medindia.net/news/Gout-Drug-Shows-Promise-72130-1.htm http://www.medindia.net/news/Kidney-Patients-May-Benefit-from-Gout-Drug-69957-1.htm A new research has suggested that a drug commonly used to treat gout may help maintain kidney disease patients' health. The study is the first to show that allopurinol treatment in patients with chronic kidney disease (CKD) decreases inflammation, slows the progression of kidney disease, and reduces patients' risk of experiencing a cardiovascular event or being hospitalized. Allopurinol is a drug used primarily to treat individuals with excess uric acid in their blood (hyperuricemia). (The ...]]> http://www.medindia.net/news/Kidney-Patients-May-Benefit-from-Gout-Drug-69957-1.htm http://www.medindia.net/news/Cheap-Gout-Drug-Found-Effective-Against-Angina-69821-1.htm A drug used for more than 40 years to treat gout can also relieve angina, say researchers. Compared to other angina drugs, allopurinol is inexpensive and appears to work by reducing the energy needs of the heart, reports the Lancet. The severe chest pain of angina occurs when the heart muscle is deprived of blood, and therefore oxygen. In the Dundee University study, 65 angina patients took part. And after analyses, boffins found that those on allopurinol could exercise for longer without getting chest pain....]]> http://www.medindia.net/news/Cheap-Gout-Drug-Found-Effective-Against-Angina-69821-1.htm http://www.medindia.net/news/Survey-Reveals-Rise-in-Number-of-Women-Suffering-from-Gout-67379-1.htm A new survey has revealed that gout is on the rise among elderly women in Britain thanks to increased cases of high blood pressure and obesity along with alcohol use. While the disease has been always associated with older men, the survey carried out by the Boston University School of Medicine revealed that 3.5 percent of women between 60 to 69 years of age suffered from gout, a number that increased to 5.6 percent among women older than 80 years. More than 2,400 women and 1,900 men were studied ...]]> http://www.medindia.net/news/Survey-Reveals-Rise-in-Number-of-Women-Suffering-from-Gout-67379-1.htm http://www.medindia.net/news/Women-With-Gout-Must-Beware-Heart-Attacks-More-Then-Men-64870-1.htm Women with gout are more likely to have a heart attack than their male counterparts with the disease, say experts. Researchers based their study on more than 9500 gout patients and 48, 000 people without the disease, aged 65 and older. Boffins followed the cardiovascular health of all the participants for an average of seven years during which as many as 3268 fatal and non-fatal heart attacks took place. The team found women with gout were 39 percent more likely to have a heart attack ...]]> http://www.medindia.net/news/Women-With-Gout-Must-Beware-Heart-Attacks-More-Then-Men-64870-1.htm http://www.medindia.net/news/Women-With-Gout-at-Greater-Risk-of-Heart-Attack-Than-Men-64778-1.htm New research published ahead of print in the IAnnals of the Rheumatic Diseases/I says that women with gout are at greater risk of a heart attack than men with the disease. Gout is known to boost the risk of a heart attack in men. But to date, little has been known about the impact of gout on women's cardiovascular health. Gout is common and caused by inflammation in the joints as a result of excess uric acid deposits. Uric acid is a by-product of purines, which are abundant in a Western diet....]]> http://www.medindia.net/news/Women-With-Gout-at-Greater-Risk-of-Heart-Attack-Than-Men-64778-1.htm http://www.medindia.net/news/Dosage-Should-Be-Increased-To-Make-Gout-Drug-Effective-60261-1.htm Dosage should be increased to make gout drug effective, say New Zealand researchers. They have established that thousands of gout sufferers may have been taking too lower dose of the most commonly used drug to effectively manage or cure this form of arthritis. Research by rheumatologist, Dr Lisa Stamp, from the University of Otago, Christchurch has found that by increasing the dose of allopurinol, the frontline drug for gout, above the current medical guidelines, 86 per centof gout sufferers reduce ...]]> http://www.medindia.net/news/Dosage-Should-Be-Increased-To-Make-Gout-Drug-Effective-60261-1.htm http://www.medindia.net/news/Scientists-Identify-Malfunctioning-Gene-Behind-Gout-53314-1.htm Johns Hopkins scientists have found that a malfunctioning gene they helped uncover last year can lead to high concentrations of blood urate that forms crystals in joint tissue and causes inflammation and pain, the hallmark of gout. The ABCG2 gene's discovery sprang from a survey of the genomes of 12,000 individuals, which was conducted to find a genetic cause for gout. Using frog egg cells genetically engineered with human DNA, the researchers have now discovered that the gene makes a ...]]> http://www.medindia.net/news/Scientists-Identify-Malfunctioning-Gene-Behind-Gout-53314-1.htm http://www.medindia.net/news/Vitamin-C-Lowers-Risk-of-Gout-in-Men-48461-1.htm Men with higher vitamin C intake appear less likely to develop gout, a painful type of arthritis, according to a report in the March 9 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. "Gout is the most common type of inflammatory arthritis in men," the authors write as background information in the article. "Epidemiologic studies suggest that the overall disease burden of gout is substantial and growing. The identification of the risk factors for gout that are modifiable ...]]> http://www.medindia.net/news/Vitamin-C-Lowers-Risk-of-Gout-in-Men-48461-1.htm http://www.medindia.net/news/New-genes-that-could-lead-to-gout-identified-42504-1.htm A new study has identified two new genes that increase the risk of higher levels of uric acid in the blood, which can lead to gout. Gout is a common, painful form of arthritis. A third gene has also been linked to the condition. All three genetic variations, taken together, are linked with up to a 40-fold increased risk in developing gout, reports Lancet. According to the findings, genetic testing could one day be used to identify individuals at risk for gout before symptoms develop, as ...]]> http://www.medindia.net/news/New-genes-that-could-lead-to-gout-identified-42504-1.htm http://www.medindia.net/news/Gout-Linked-to-Higher-Risk-of-Death-Due-to-Heart-Disease-37565-1.htm According to a new study men with risk factors for heart disease, have a greater risk of dying from heart problems if they have the arthritic condition gout. Researchers studied over 9000 middle-aged men at higher-than- average risk of heart disease, and found that those with gout were more likely to die of a heart attack or other cardiovascular causes such as stroke over 17 years. Lead researcher Dr. Eswar Krishnan, an assistant professor at Stanford University School of Medicine observed that ...]]> http://www.medindia.net/news/Gout-Linked-to-Higher-Risk-of-Death-Due-to-Heart-Disease-37565-1.htm http://www.medindia.net/news/Genetic-Variation-may-Raise-the-Risk-of-Gout-33964-1.htm Gout has long been believed to be caused by unhealthy lifestyles, but now researchers at the MRC Human Genetics Unit, in Edinburgh have found that a gene variant may also raise the risk of this painful joint condition. The researcher team, led by Professor Alan Wright, analysed more than 12,000 people and said that new gout drugs may one day target the gene, called SLC2A, and the protein it controls. The susceptibility of Gout can vary from person to person- some people may have higher or lower ...]]> http://www.medindia.net/news/Genetic-Variation-may-Raise-the-Risk-of-Gout-33964-1.htm http://www.medindia.net/news/Soda-and-Sugary-Drinks-Blamed-for-Surge-in-Gout-Amongst-Men-32498-1.htm A surge in the painful joint condition called gout among American men is linked to a rise in drinking sodas and other sugary soft drinks, a study published Friday suggests. In an unusually long-term study, more than 51,000 male dentists, pharmacists and veterinarians aged 40 years or more in the United States and Canada filled in questionnaires on their health, weight, medications and diet, and updated the information every two years thereafter. Those who were already diagnosed with gout ...]]> http://www.medindia.net/news/Soda-and-Sugary-Drinks-Blamed-for-Surge-in-Gout-Amongst-Men-32498-1.htm http://www.medindia.net/news/Prevalence-of-High-Rates-of-Gout-in-Pacific-Island-Linked-to-Hereditary-29707-1.htm The high rates of gout reported among Maori and Pacific Island males could be an ailment inherited over thousands of years to the time when Polynesia and Melanesia were being colonized from South East Asia. According to Dr. Hallie Buckley, a biological anthropologist working for the University of Otago, and colleagues from the Australian National University and CNRS in Paris, Pacific Island males suffered from possible gouty arthritis. Dr. Buckley and her other colleagues based their findings ...]]> http://www.medindia.net/news/Prevalence-of-High-Rates-of-Gout-in-Pacific-Island-Linked-to-Hereditary-29707-1.htm http://www.medindia.net/news/Incapacity-Benefit-Claimants-in-UK-Cite-Tiredness-and-Gout-as-Reasons-29526-1.htm People in the UK cite tiredness, gout and acne as key reasons for being unable to work and seeking government doles. According to a Department of Work and Pensions(DWP) document disclosed under the Freedom of Information Act, people of working age mention 480 different problems for their unemployability. The incapacity benefits are estimated to cost the government 7.5bn annually. Thus far it had been believed that a huge proportion of them actually suffer from mental illnesses and alcoholism....]]> http://www.medindia.net/news/Incapacity-Benefit-Claimants-in-UK-Cite-Tiredness-and-Gout-as-Reasons-29526-1.htm http://www.medindia.net/news/Phase-III-Study-Reveals-Potential-New-Therapy-for-Gout-29231-1.htm Rilonacept (IL-1 Trap) may substantially decrease both disease activity and pain in patients with chronic active gout, according to research presented this week at the American College of Rheumatology Annual Scientific Meeting in Boston, Mass. Gout is a painful and potentially disabling form of arthritis that has been recognized since ancient times. Initial symptoms usually consist of intense episodes of painful swelling in single joints, most often in the feet, especially the big toe. Rilonacept, ...]]> http://www.medindia.net/news/Phase-III-Study-Reveals-Potential-New-Therapy-for-Gout-29231-1.htm http://www.medindia.net/news/Four-Cups-of-Coffee-a-Day-may-Cut-Down-the-Risk-of-Gout-21292-1.htm Coffee is widely consumed beverage and is regularly investigated and debated for its impact on health conditions from breast cancer to heart disease. Among its complex effects on the body, coffee or its components have been linked to lower insulin and uric acid levels on a short-term basis or cross-sectionally. These and other mechanisms suggest that coffee consumption may affect the risk of gout, the most prevalent inflammatory arthritis in adult males. To examine how coffee consumption might ...]]> http://www.medindia.net/news/Four-Cups-of-Coffee-a-Day-may-Cut-Down-the-Risk-of-Gout-21292-1.htm http://www.medindia.net/news/view_news_main.asp?x=15883 Climatic factors such as heat and humidity that lead to dehydration can signal a future attack for gout sufferers, according to research presented this week at the American College of Rheumatology Annual Scientific Meeting in Washington DC. Gout, caused by deposits of monosodium uric crystals, causes severe pain and swelling of the joints. The attacks, which typically affect one joint over a period of a few days, most often the big toe, can also generate fever, chills, a general feeling of malaise and rapid heartbeat....]]> http://www.medindia.net/news/view_news_main.asp?x=15883 http://www.medindia.net/news/view_news_main.asp?x=13082 Gout increases the risk of suffering a heart attack, according to new research from University of Pittsburgh School of Medicine.The study is published in the August edition of the journal Arthritis (and) Rheumatism and the full article is available on line at http:www3.interscience.wiley.com/cgibin/jhome/76509746 This is the first time that researchers have demonstrated that people having no risk of coronary heart disease could be at risk for heart attack due to gout. Gout is a metabolic disease ...]]> http://www.medindia.net/news/view_news_main.asp?x=13082 http://www.medindia.net/news/view_news_main.asp?x=6183 A new drug called febuxostat has been found to reduce plasma levels of uric acid more effectively in Gout than the currently used drug allopurinol. If the results of the clinical trial are successful, then it would mean the end of a 40 year search for successful treatment of Gout. Gout is characterized by accumulation and deposition of needle shaped uric acid crystals in the joints, thereby leading to inflammation and pain. Progressively, it leads to a condition called 'Gouty arthritis' and is ...]]> http://www.medindia.net/news/view_news_main.asp?x=6183 http://www.medindia.net/news/view_news_main.asp?x=2687 http://www.medindia.net/news/view_news_main.asp?x=2687 http://www.medindia.net/news/view_news_main.asp?x=2597 http://www.medindia.net/news/view_news_main.asp?x=2597 http://www.medindia.net/news/view_news_main.asp?x=622 http://www.medindia.net/news/view_news_main.asp?x=622