http://www.medindia.net/healthnews/cystic-fibroris-news.asp Medindia largest health website in india. en-us Copyright 2012. All Rights Reserved. Fri, 25 May 2012 05:16:37 GMT http://www.medindia.net/news/danger-detected-in-standard-treatment-for-a-grave-lung-disease-101644-1.htm Three drugs combined and administered globally as the standard of care for a grave lung disease is fatally life-threatening to people, and must be refrained from using together to treat the disease, called idiopathic pulmonary fibrosis, states the startling results of a rigorous independent study. The study, which will appear online May 20 in the iNew England Journal of Medicine/i to coincide with a presentation at the annual meeting of the American Thoracic Society, was conducted by IPF ...]]> http://www.medindia.net/news/danger-detected-in-standard-treatment-for-a-grave-lung-disease-101644-1.htm http://www.medindia.net/news/tb-raises-lung-cancer-mortality-risk-in-elderly-101636-1.htm Elderly patients who have tuberculosis are at increased risk of dying from lung cancer, finds a new study. "There is a high incidence of both tuberculosis and lung cancer among the elderly in Hong Kong," said lead author Chi Chiu Leung, MBBS, consultant chest physician in the Tuberculosis and Chest Service of the Department of Health of Hong Kong. "In our prospective follow-up study of a cohort of 61,239 subjects aged 65 years or older, we found that active tuberculosis was an independent predictor ...]]> http://www.medindia.net/news/tb-raises-lung-cancer-mortality-risk-in-elderly-101636-1.htm http://www.medindia.net/news/prenatal-exposure-to-polluted-air-may-compromise-development-of-lung-function-101567-1.htm A new study conducted by researchers at University of California, Berkeley has found that exposure of asthmatic children to polluted air when still in the womb may harm the development of their lung function. The researchers used data from the US Environmental Protection Agency and also observed 162 asthmatic children aged between 6 and 15 years of age. All of the participants were from Fresno, California. The researchers found that those children who were exposed to nitrogen dioxide and other ...]]> http://www.medindia.net/news/prenatal-exposure-to-polluted-air-may-compromise-development-of-lung-function-101567-1.htm http://www.medindia.net/news/molecular-biomarkers-in-tissue-and-lining-of-lungs-provide-another-technique-for-lung-cancer-screening-101478-1.htm Using the molecular biomarkers present in the tissue and fluid lining of the lungs may be another technique that can be used in lung cancer screening, according to a new study published in the Journal of Thoracic Oncology. Since the National Lung Screening Trial found that 96.4 percent of the positive CT screening results were false positive, scientists have been looking for ways to more accurately diagnose patients. This research focused on a way to determine if the nodules detected by the CT screening, are in fact malignant or benign....]]> http://www.medindia.net/news/molecular-biomarkers-in-tissue-and-lining-of-lungs-provide-another-technique-for-lung-cancer-screening-101478-1.htm http://www.medindia.net/news/lung-cancer-screening-via-video-assisted-thoracic-surgery-101444-1.htm Video assisted thoracic surgery (VATS) is a valuable tool in managing lesions detected in a lung cancer screening program, according to the most recent research released in June's iJournal of Thoracic Oncology/i. The primary objective of lung cancer screening with low dose computer tomography (CT) is to detect lung cancer at an early stage and thus amenable to a complete surgical resection, the only established cure for lung cancer. Lung cancer currently has no standard screening program ...]]> http://www.medindia.net/news/lung-cancer-screening-via-video-assisted-thoracic-surgery-101444-1.htm http://www.medindia.net/news/response-to-lung-cancer-therapy-probably-resolved-by-molecular-subtypes-and-genetic-alterations-101281-1.htm Cancer therapies aiming precise molecular subtypes of the disease grants physicians to customise treatment to a person's individual molecular profile. But scientists are finding that in many types of cancer the molecular subtypes are more varied than previously thought and contain further genetic alterations that can affect a patient's response to therapy. A UNC-led team of scientists has shown for the first time that lung cancer molecular subtypes correlate with distinct genetic alterations and with patient response to therapy....]]> http://www.medindia.net/news/response-to-lung-cancer-therapy-probably-resolved-by-molecular-subtypes-and-genetic-alterations-101281-1.htm http://www.medindia.net/news/viruses-can-result-in-acute-attacks-of-chronic-lung-diseases-101187-1.htm Viral infection of the respiratory tract is linked to acute attacks of respiratory diseases like asthma, COPD and cystic fibrosis. Viruses are found everywhere and are responsible for some of the worst and incurable infections. Chronic obstructive pulmonary disease (COPD) is known to be the fourth leading cause of global mortality. Recent researches have revealed that by the year 2020, it will become the third leading cause. Rhinoviruses not only cause common cold but are also responsible for COPD exacerbations....]]> http://www.medindia.net/news/viruses-can-result-in-acute-attacks-of-chronic-lung-diseases-101187-1.htm http://www.medindia.net/news/persistent-cough-could-be-a-sign-of-lung-cancer-100989-1.htm Continuous cough could signal lung cancer, warns new government advertising drive. The campaign, which is being run in TV, radio, print and online media, recommends people with coughs lasting three weeks visit their GP. Research has shown that the public are much more aware that lumps and bleeding are warning signs of cancer than a cough, but the ads make clear persistent coughs should also raise alarm bells. The push is being backed by celebrities including comedian and actor ...]]> http://www.medindia.net/news/persistent-cough-could-be-a-sign-of-lung-cancer-100989-1.htm http://www.medindia.net/news/lung-cancer-risk-influenced-by-genetic-variants-and-tobacco-exposure-100646-1.htm Lung cancer risk is largely mediated by level of tobacco exposure as there is an association between the rs1051730-rs16969968 genotype and objective measures of tobacco exposure. These are the findings of a study published April 25 in the iJournal of the National Cancer Institute/i. The rs1051730-rs16969968 genotype is known to be associated with heaviness of smoking, lung cancer risk, and other smoking-related outcomes. Prior studies have generally depended on self-reported smoking behavior, ...]]> http://www.medindia.net/news/lung-cancer-risk-influenced-by-genetic-variants-and-tobacco-exposure-100646-1.htm http://www.medindia.net/news/gene-critical-to-development-and-spread-of-lung-cancer-identified-100546-1.htm Researchers have discovered a single gene that promotes initial development of most common form of lung cancer. The study, published in the journal on April 24, shows that MMP-10 is a growth factor secreted and then used by cancer stem-like cells to keep themselves vital. These cells then drive lung cancer and its spread, and are notoriously immune to conventional treatment. The findings raise hope for a possible treatment for non-small cell lung cancer, the leading cause of U.S....]]> http://www.medindia.net/news/gene-critical-to-development-and-spread-of-lung-cancer-identified-100546-1.htm http://www.medindia.net/news/opioids-improve-quality-of-life-in-obstructive-lung-disease-patients-100545-1.htm Opioids effective in relieving shortness of breath and thereby improving quality of life in chronic obstructive pulmonary disease (COPD) patients, reveals research published in Canadian Medical Association Journal. The prevalence of COPD in Canada is increasing, and shortness of breath (dyspnea) is a major symptom that is difficult to treat and can result in fear, anxiety and a decreased quality of life. Although opioids are often used to treat pain and dyspnea associated with malignant diseases, they are underused in COPD treatment....]]> http://www.medindia.net/news/opioids-improve-quality-of-life-in-obstructive-lung-disease-patients-100545-1.htm http://www.medindia.net/news/study-says-hispanic-lung-cancer-patients-tend-to-live-longer-than-blacks-and-whites-100519-1.htm Hispanic lung cancer patients live longer than white or black patients, shows study published in Cancer. Most studies that look at ethnic and racial disparities in lung cancer compare black patients with whites. To see how Hispanics compare with other ethnicities with regards to survival after a lung cancer diagnosis, Ali Saeed, an MD/PhD candidate, and Brian Lally, MD, of the University of Miami Miller School of Medicine, led a team that analyzed patient information from the Survival, ...]]> http://www.medindia.net/news/study-says-hispanic-lung-cancer-patients-tend-to-live-longer-than-blacks-and-whites-100519-1.htm http://www.medindia.net/news/lethal-bacterial-infection-in-cystic-fibrosis-patients-insight-100498-1.htm The reason for a certain type of bacteria, harmless in healthy people, is so deadly to patients with cystic fibrosis has been discovered by scientists. The bacterium, IBurkholderia cenocepacia,/I causes a severe and persistent lung infection in patients with CF and is resistant to nearly all known antibiotics. Cystic fibrosis is a chronic disorder characterized by a buildup of mucus in the lungs and other parts of the body, and various types of lung infection are responsible for about 85 percent of deaths in these patients....]]> http://www.medindia.net/news/lethal-bacterial-infection-in-cystic-fibrosis-patients-insight-100498-1.htm http://www.medindia.net/news/risk-of-relapse-in-lung-cancer-patients-may-be-identified-by-gene-signature-100393-1.htm In a study presented at the 3rd European Lung Cancer Conference in Geneva, Spanish researchers revealed that they have identified a new genetic signature that could help doctors assess whether a patient with early stage lung cancer is at a greater risk of suffering from a relapse after surgery. Their work also opens new avenues for immunotherapy for lung cancer. Non-small cell lung cancer is a disease that is often not diagnosed until it has grown and spread throughout the body. Even those ...]]> http://www.medindia.net/news/risk-of-relapse-in-lung-cancer-patients-may-be-identified-by-gene-signature-100393-1.htm http://www.medindia.net/news/use-of-erlotinib-in-advanced-non-small-cell-lung-cancer-may-be-guided-by-new-analysis-100392-1.htm Researchers have revealed that patients with advanced non-small cell lung cancer should only receive treatment with the drug erlotinib before receiving standard chemotherapy if their tumor is known to harbor EGFR mutations. The study was presented at the 3rd European Lung Cancer Conference in Geneva, Switzerland. The results of biomarker analyses of a recently reported clinical trial confirm that patients with unknown or negative mutation status should be treated with the standard chemotherapy first, they say....]]> http://www.medindia.net/news/use-of-erlotinib-in-advanced-non-small-cell-lung-cancer-may-be-guided-by-new-analysis-100392-1.htm http://www.medindia.net/news/new-studies-to-be-presented-at-lung-cancer-conference-in-geneva-100366-1.htm The 3rd European Lung Cancer Conference in Geneva will see experts present a number of studies that can help doctors to customize lung cancer treatment depending on the characteristics of the individual patients. "A major goal of lung cancer treatment is to tailor the treatment to the individual," says Dr Fiona Blackhall from The Christie NHS Foundation Trust in Manchester, UK. "The studies that will be presented at ELCC 2012 are important practical steps to achieving this in the clinic. Methods ...]]> http://www.medindia.net/news/new-studies-to-be-presented-at-lung-cancer-conference-in-geneva-100366-1.htm http://www.medindia.net/news/drug-added-to-customary-chemotherapy-does-not-offer-survival-benefit-for-older-lung-cancer-patients-100309-1.htm Drug bevacizumab (Avastin) added to the standard chemotherapy regimen for non-small cell lung cancer (NSCLC), an approach authorised by the FDA in 2006, did not lead to notably boost survival rates for patients over the age of 65 enrolled in Medicare, state findings by researchers of a new study by Dana-Farber Cancer Institute. The study is being published in the April 18 iJournal of the American Medical Association/i, a these issue on comparative effectiveness research. "Effectiveness ...]]> http://www.medindia.net/news/drug-added-to-customary-chemotherapy-does-not-offer-survival-benefit-for-older-lung-cancer-patients-100309-1.htm http://www.medindia.net/news/research-into-follow-up-care-for-lung-cancer-vital-100196-1.htm A new study published in the International Association for the Study of Lung Cancer's (IASLC) Journal of Thoracic Oncology underlines the importance of looking into all aspects of follow-up care provided to patients with lung cancer. After searching the published literature and databases, researchers analyzed four studies and could not determine that one method was preferred over another. "Thus it is clear that more prospective research is needed in this area, ideally in the form of well-designed ...]]> http://www.medindia.net/news/research-into-follow-up-care-for-lung-cancer-vital-100196-1.htm http://www.medindia.net/news/genetic-variations-linked-with-risk-of-lung-cancer-100177-1.htm A new study published in the Journal of Thoracic Oncology has confirmed that some genetic variations increase the risk of lung cancer. Researchers looked at the genetics of 716 Japanese patients with lung cancer and 716 without. They found, "the variants rs12914385, rs1317286 and rs931794 localized to the CHRNA5-CHRNA3-CHRNB4 cluster on chromosome 15q25 modified the impact of cigarette smoking on lung cancer risk, but showed no statistically significant major effect on the risk of lung cancer....]]> http://www.medindia.net/news/genetic-variations-linked-with-risk-of-lung-cancer-100177-1.htm http://www.medindia.net/news/proteomic-biomarker-analysis-of-lung-cancer-tissue-samples-100159-1.htm By means of proteomic assay technology researchers identified significant expression changes in lung cancer tissue samples. "Early detection of NSCLC can dramatically improve the prognosis for patients with the disease, as has been shown recently through the use of CT-scans in a high-risk population of heavy smokers," said Sheri Wilcox, Ph.D., Director of Discovery Sciences at SomaLogic. "However, this approach has a high false-positive rate, which can result in overdiagnosis and unnecessary treatment....]]> http://www.medindia.net/news/proteomic-biomarker-analysis-of-lung-cancer-tissue-samples-100159-1.htm http://www.medindia.net/news/acute-lung-injury-survivors-have-long-term-neuropsychological-impairment-99947-1.htm A new study has revealed that cognitive and psychiatric impairments are common among long-term survivors of acute lung injury (ALI). The study also stressed that these impairments can be assessed using a telephone-based test battery. "Neuropsychological impairment is increasingly being recognized as an important outcome among survivors of critical illness, but neuropsychological function in long-term ALI survivors has not been assessed in a multi-center trial, and evidence on the etiology of ...]]> http://www.medindia.net/news/acute-lung-injury-survivors-have-long-term-neuropsychological-impairment-99947-1.htm http://www.medindia.net/news/purified-lung-and-thyroid-progenitors-derived-from-embryonic-stem-cells-bu-researchers-99939-1.htm A population of pure lung and thyroid progenitor cells in vitro has been derived that successfully mimics the developmental milestones of lung and thyroid tissue formation. The study was by researchers at Boston University School of Medicine (BUSM) and Boston Medical Center (BMC). The research, which will be published in the April 6 edition of the journal ICell Stem Cell/I, identifies factors necessary for embryonic stem cells to differentiate into lung progenitor cells and provides key information ...]]> http://www.medindia.net/news/purified-lung-and-thyroid-progenitors-derived-from-embryonic-stem-cells-bu-researchers-99939-1.htm http://www.medindia.net/news/combination-therapy-may-help-patients-with-lung-cancer-who-are-ineligible-for-bevacizumab-99900-1.htm New research indicates that patients with non-small cell lung cancer ineligible for treatment with bevacizumab may be helped by a combination of nab-paclitaxel and carboplatin. The data was presented at the AACR Annual Meeting 2012. "The combination of carboplatin and nab-paclitaxel demonstrates promising efficacy with tolerable toxicity in patients with non-small cell lung cancer (NSCLC) ineligible for therapy with bevacizumab," said Gregory A. Otterson, M.D., professor of internal medicine, ...]]> http://www.medindia.net/news/combination-therapy-may-help-patients-with-lung-cancer-who-are-ineligible-for-bevacizumab-99900-1.htm http://www.medindia.net/news/treatment-with-new-lung-cancer-enhanced-with-drug-clinical-insight-99889-1.htm Men go through a distinct fall in their testosterone levels when taking a targeted therapy to control a particular type of lung cancer. That's according to a University of Colorado Cancer Center study published in the April issue of ICancer,/I the official journal of the American Cancer Society. Investigators at CU Cancer Center looked at the hormone levels in men with anaplastic lymphoma kinase (ALK) positive advanced non-small cell lung cancer (NSCLC) taking crizotinib, after a 35-year-old ...]]> http://www.medindia.net/news/treatment-with-new-lung-cancer-enhanced-with-drug-clinical-insight-99889-1.htm http://www.medindia.net/news/researchers-report-major-advance-against-cystic-fibrosis-99812-1.htm The possibility of discovering a drug in the near future to control cystic fibrosis (CF) has been given a major boost by Harvard stem cell researchers at Massachusetts General Hospital (MGH). Cystic fibrosis is a fatal lung disease that claims about 500 lives each year, with 1,000 new cases diagnosed annually. Beginning with the skin cells of patients with CF, Jayaraj Rajagopal, MD, and colleagues first created induced pluripotent stem (iPS) cells, and then used those cells to create human ...]]> http://www.medindia.net/news/researchers-report-major-advance-against-cystic-fibrosis-99812-1.htm http://www.medindia.net/news/livers-part-in-averting-dissemination-of-lung-infection-busm-researchers-reveal-99770-1.htm Regulation and functional importance of the acute phase response during a lung infection found by researchers at Boston University School of Medicine (BUSM). The findings, which will be published in the May edition of the IJournal of Clinical Investigation/I, demonstrate that the liver responds in order to increase defenses in the blood that prevent localized infections from spreading throughout the body. The study was led by Joseph P. Mizgerd, Sc.D., professor of medicine, microbiology and biochemistry at BUSM, and Lee J....]]> http://www.medindia.net/news/livers-part-in-averting-dissemination-of-lung-infection-busm-researchers-reveal-99770-1.htm http://www.medindia.net/news/lung-cancer-affects-many-shanghai-women-99757-1.htm Media reports indicate that lung cancer is affecting more women than men in the Chinese metropolis of Shanghai. The number of women with lung cancer rose 38.4 percent over the past five years while the growth rate for men was 16.9 percent, the Shanghai Daily reported. However, men were still far more likely to get the deadly disease. The incidence of lung cancer among men was 88 per 100,000 people and 30 among women. An expert said the rise in female cases has resulted due to many young women taking up smoking....]]> http://www.medindia.net/news/lung-cancer-affects-many-shanghai-women-99757-1.htm http://www.medindia.net/news/multiple-genes-linked-to-differences-in-cystic-fibrosis-identified-99740-1.htm One in every 3,600 children born in Canada has cystic fibrosis, which is a debilitating disease caused by mutations in the CFTR gene. Researchers have long been puzzled as to how individuals who carry the same CFTR mutations can experience such different courses of disease. Patients with CF are affected in multiple organs such as the lungs, pancreas and liver, to varying degrees. An international team led by The Hospital for Sick Children (SickKids) and the University for Toronto (U of T) has found a potential answer to this puzzle....]]> http://www.medindia.net/news/multiple-genes-linked-to-differences-in-cystic-fibrosis-identified-99740-1.htm http://www.medindia.net/news/newborns-with-cystic-fibrosis-have-gene-variations-that-could-cause-intestinal-blockage-99626-1.htm Several regions of the genome that may predispose cystic fibrosis (CF) patients to develop an intestinal blockage even while in the womb have been identified by University of North Carolina at Chapel Hill researchers working as part of the International Cystic Fibrosis Consortium. A report of this international study appears online April 1, 2012 in the journal iNature Genetics/i. It was the work of the North America CF Gene Modifier Consortium, which brought together dozens of investigators ...]]> http://www.medindia.net/news/newborns-with-cystic-fibrosis-have-gene-variations-that-could-cause-intestinal-blockage-99626-1.htm http://www.medindia.net/news/observation-kids-with-lung-function-deficits-as-neonates-develop-asthma-99602-1.htm Kids who develop asthma by age seven have inadequacies in lung function and augmented bronchial responsiveness as neonates, suggests a new study from researchers in Denmark. "Previous research on the relationship between neonatal lung function and the development of asthma has been conflicting," said lead author Hans Bisgaard, MD, DMSci, professor of pediatrics at the University of Copenhagen and head of the Danish Pediatric Asthma Centre. "Our study shows that children with asthma by age seven ...]]> http://www.medindia.net/news/observation-kids-with-lung-function-deficits-as-neonates-develop-asthma-99602-1.htm http://www.medindia.net/news/survival-in-people-with-acute-lung-injury-increased-by-reducing-breath-size-from-icu-ventilator-99534-1.htm A study by critical care experts at Johns Hopkins has suggested that mortality risk is reduced by almost 8 percent by carefully adjusting mechanical ventilator settings in the intensive care unit to pump smaller breaths into very sick lungs. Study participants were evaluated for two years after their acute lung injury. "Adjusting the ventilator to keep the breath size and lung pressures lower can have a dramatic effect on whether or not a patient dies from their lung injury, even long after ...]]> http://www.medindia.net/news/survival-in-people-with-acute-lung-injury-increased-by-reducing-breath-size-from-icu-ventilator-99534-1.htm http://www.medindia.net/news/ct-scans-more-effective-than-traditional-methods-in-detecting-lung-cancer-99527-1.htm CT scans are more effective in detecting lung cancer, than the traditional methods, at identifying aggressive lung cancers in their most treatable stages. The data, published online March 27 in the journal IRadiology/I, demonstrate that lung cancers found through annual CT screening are similar to those found in routine practice, both in terms of tumor growth rates and cell-type distribution. In fact, the report showed that 79 percent of the cases diagnosed through annual repeat CT scans ...]]> http://www.medindia.net/news/ct-scans-more-effective-than-traditional-methods-in-detecting-lung-cancer-99527-1.htm http://www.medindia.net/news/extensive-study-probes-new-concerns-on-antibiotic-use-for-cystic-fibrosis-99477-1.htm When concerning treating cystic fibrosis, the existing standard of aggressive antibiotic treatments may not at all times be the best answer, discovers a decade-long study led by researchers at the University of Michigan. Traditionally, bacteria-blasting antibiotics are used to suppress infection in CF patients'' lungs to the lowest level possible, but maintaining a diversity of bacterial communities may help some patients stay healthy longer, says the study''s senior author, John J. LiPuma, M....]]> http://www.medindia.net/news/extensive-study-probes-new-concerns-on-antibiotic-use-for-cystic-fibrosis-99477-1.htm http://www.medindia.net/news/blocked-lung-blood-vessels-novel-drug-in-pill-form-safer-than-standard-approach-99452-1.htm A new study has revealed that a novel oral anti-coagulant outperformed the injected standard therapy on important safety measures for the treatment of pulmonary embolism. These are the findings from the EINSTEIN-PE trial presented today at the American College of Cardiology's 61st Annual Scientific Session. The Scientific Session, the premier cardiovascular medical meeting, brings cardiovascular professionals together to further advances in the field. Pulmonary embolism (PE) and deep vein ...]]> http://www.medindia.net/news/blocked-lung-blood-vessels-novel-drug-in-pill-form-safer-than-standard-approach-99452-1.htm http://www.medindia.net/news/radiation-exposure-reduced-by-lower-dosage-ct-guided-lung-biopsy-protocol-99448-1.htm Radiation exposure is significantly reduced by new guidelines for CT-guided biopsies of lung nodules, thus allowing individuals to benefit from the procedure. This research is being presented at the Society of Interventional Radiology's 37th Annual Scientific Meeting in San Francisco, Calif. "The published early results of a trial using computed tomography to detect lung nodules demonstrated that screening with low-dose CT reduced mortality from lung cancer by 20 percent compared to screening ...]]> http://www.medindia.net/news/radiation-exposure-reduced-by-lower-dosage-ct-guided-lung-biopsy-protocol-99448-1.htm http://www.medindia.net/news/study-says-pill-works-as-well-against-lung-clots-as-injection-99376-1.htm A new study has found that a new kind of blood thinner that comes in a pill form works as well as injection therapy to ward off blood clots in the lungs. The drug is made by German drug giant Bayer. Xarelto, or rivaroxaban, was tested in an international phase III clinical trial as a treatment to treat or prevent a recurrence of venous thromboembolism, the third most common kind of cardiovascular disease, which can strike the legs or the lungs. Pulmonary embolism, or clots in the lungs, are third leading cause of death in US hospitals....]]> http://www.medindia.net/news/study-says-pill-works-as-well-against-lung-clots-as-injection-99376-1.htm http://www.medindia.net/news/stigma-ups-depression-in-lung-cancer-patients-study-99313-1.htm Researchers link stigma to depression among patients with lung cancer, reveals study. Researchers at Moffitt Cancer Center in Tampa, Fla., found that these factors may contribute to depression at rates higher than experienced by patients with other kinds of cancer. "To the best of our knowledge, this is the first study to examine the relationship of perceived stigma to depressive symptomology in lung cancer patients," said study co-author Paul B. Jacobsen, Ph.D., Moffitt's associate center director for Population Sciences....]]> http://www.medindia.net/news/stigma-ups-depression-in-lung-cancer-patients-study-99313-1.htm http://www.medindia.net/news/rnai-could-enhance-lung-cancer-treatment-99150-1.htm Blocking the production of epidermal growth factor receptor using RNAi could enhance the effect of tyrosine kinase inhibitors on lung cancer cell death, shows study published in BMC Medicine. There are 1.2 million new cases of lung cancer worldwide every year and about 75-85% of these are NSCLC. 10% of cases with NSCLC have a mutation in the gene responsible for making EGFR, and three quarters of these patients respond well to TKIs. However others are unresponsive, and, even for the people ...]]> http://www.medindia.net/news/rnai-could-enhance-lung-cancer-treatment-99150-1.htm http://www.medindia.net/news/impact-of-wine-on-lung-function-98624-1.htm Moderate wine consumption can have a positive effect on lung function, suggest researchers. The research team from the Netherlands also looked at genetic factors and mechanisms by which resveratrol might be absorbed by the body and its possible effect on longevity of life. They found that pure resveratrol intake was associated with higher lung volumes and that white wine intake (but not red wine intake) and was associated with lower risk of airway obstruction. They also report that ...]]> http://www.medindia.net/news/impact-of-wine-on-lung-function-98624-1.htm http://www.medindia.net/news/latest-treatment-with-inhaled-interferon-may-boost-lung-function-in-pulmonary-fibrosis-98368-1.htm While treating for diopathic pulmonary fibrosis (IPF), a chronic and progressive form of lung disease caused by excessive formation of fibrotic, or scar tissue, in the lungs, inhaled interferon-gamma may be effective, states an article published in iJournal of Aerosol Medicine and Pulmonary Drug Delivery/i. Normally, systemic delivery of interferon-gamma can cause substantial side effects; however, delivery of aerosolized interferon-gamma directly into the lungs was shown to be safe and ...]]> http://www.medindia.net/news/latest-treatment-with-inhaled-interferon-may-boost-lung-function-in-pulmonary-fibrosis-98368-1.htm http://www.medindia.net/news/diesel-exhaust-increases-lung-cancer-risk-98314-1.htm A two-decade long study conducted by National Cancer Institute in the United States has found that diesel exhaust increases the risk of lung cancer. The researchers tracked more than 12,000 miners working in mines such as potash and lime where diesel powered equipments are widely used. In the report, published in the Journal of the National Cancer Institute, the researchers wrote that those who were the most exposed to harmful fumes were three times more likely to die due to lung cancer. While ...]]> http://www.medindia.net/news/diesel-exhaust-increases-lung-cancer-risk-98314-1.htm http://www.medindia.net/news/what-causes-lung-injury-in-severe-flu-98224-1.htm On the one hand some scientists report engineering a super virulent strain of the H5N1 influenza virus, which has the potential to wipe out a significant percentage of the human population. On the other hand another group of researchers from the United Kingdom now report a discovery that may one day help mitigate the deadly effects of all flu strains. This report, appearing in the March 2012 print issue of the http:www.jleukbio.org"IJournal of Leukocyte Biology/I, describes findings that ...]]> http://www.medindia.net/news/what-causes-lung-injury-in-severe-flu-98224-1.htm http://www.medindia.net/news/elderly-lung-cancer-patients-may-not-get-survival-benefit-with-common-postoperative-radiotherapy-97581-1.htm Post-operative radiation therapy (PORT) may not prolong life in older people with locally advanced disease, according to researchers from Mount Sinai School of Medicine. PORT is a controversial yet frequently administered treatment for lung cancer, The findings appear in the February 13 online edition of ICancer/I, a peer-reviewed journal of the American Cancer Society. In patients with non-small cell lung cancer (NSCLC), the standard of care is surgery to remove the tumor. However, ...]]> http://www.medindia.net/news/elderly-lung-cancer-patients-may-not-get-survival-benefit-with-common-postoperative-radiotherapy-97581-1.htm http://www.medindia.net/news/scientists-identify-potential-therapeutic-target-for-tobacco-related-lung-cancers-97410-1.htm The immune response regulator IKBKE (serine/threonine kinase) plays two roles in tobacco-related non-small cell lung cancers, say researchers. Tobacco carcinogens induce IKBKE and, in turn, IKBKE induces chemotherapy resistance. "IKBKE is a newly identified oconogene, a gene linked to cancer," said study lead author Jin Q. Cheng, Ph.D., M.D., who studies genetic alterations and their molecular mechanisms in cancer. "In our study, we demonstrated that IKBKE is a STAT 3 target gene and is induced by tobacco....]]> http://www.medindia.net/news/scientists-identify-potential-therapeutic-target-for-tobacco-related-lung-cancers-97410-1.htm http://www.medindia.net/news/maintenance-of-spinal-mobility-improves-lung-function-in-ankylosing-spondylitis-97272-1.htm bPatients with ankylosing spondylitis suffer from reduced lung function. A recent study emphasizes the importance of maintaining spinal mobility in the management of this disease. /b Ankylosing spondylitis is a chronic inflammatory disease of joints that causes pain and stiffness in and around the spine. The spine is made up of individual bones called the vertebrae that are stacked over one another. Spondylitis refers to inflammation of the joints between two vertebrae; over time ...]]> http://www.medindia.net/news/maintenance-of-spinal-mobility-improves-lung-function-in-ankylosing-spondylitis-97272-1.htm http://www.medindia.net/news/risk-factors-associated-with-bleeding-in-lung-cancer-97267-1.htm bMassive acute bleeding in the lung, called pulmonary hemorrhage (PH), is a fatal complication seen in lung cancer patients treated with chemotherapy and/or radiotherapy./b A recent study has unveiled the risk factors that predispose patients to pulmonary hemorrhage; bmajor/b blung cavities and squamous cell variant of lung cancer are independently associated with PH./b Chemoradiotherapy, a combination of chemotherapy and radiotherapy, is a widely used mode of treatment for patients with lung cancer....]]> http://www.medindia.net/news/risk-factors-associated-with-bleeding-in-lung-cancer-97267-1.htm http://www.medindia.net/news/lung-cancer-testing-is-required-confirms-new-research-97098-1.htm Diverse types of lung cancer act in different ways, signifying they are essentially different diseases. According to a University of Colorado Cancer Center study published in ICancer/I, the official journal of the American Cancer Society, different subgroups of non-small cell lung cancer (NSCLC) show distinct patterns of spread in the body. The study looked at 209 patients diagnosed with stage IV non-small cell lung cancer separated into four different molecular subgroups using testing ...]]> http://www.medindia.net/news/lung-cancer-testing-is-required-confirms-new-research-97098-1.htm http://www.medindia.net/news/lung-cancer-may-be-combated-in-a-better-manner-with-combination-drug-therapy-97039-1.htm A study by the Translational Genomics Research Institute (TGen) and Van Andel Research Institute (VARI) has stressed that combination drug therapy may be needed to combat non-small cell lung cancer (NSCLC). The study, "STAT3 is Activated by JAK2 Independent of Key Oncogenic Driver Mutation in Non-Small Cell Lung Carcinoma," was published online today, Feb. 2, 2012, by the IPublic Library of Science (PLoS) ONE/I. The study found that in NSCLC - the most common form of lung cancer - that ...]]> http://www.medindia.net/news/lung-cancer-may-be-combated-in-a-better-manner-with-combination-drug-therapy-97039-1.htm http://www.medindia.net/news/new-genetic-subtype-of-lung-cancer-defined-by-massachusetts-general-study-97011-1.htm The Massachusetts General Hospital (MGH) Cancer Center's investigators' report has defined the role of a recently keyed gene abnormality in a lethal form of lung cancer. Tumors driven by rearrangements in the ROS1 gene represent 1 to 2 percent of non-small-cell lung cancers (NSCLC), the leading cause of cancer death in the U.S. The researchers show that ROS1-driven tumors can be treated with crizotinib, which also inhibits the growth of tumors driven by an oncogene called ALK, and describe the ...]]> http://www.medindia.net/news/new-genetic-subtype-of-lung-cancer-defined-by-massachusetts-general-study-97011-1.htm http://www.medindia.net/news/state-of-lung-transplantation-system-96884-1.htm The current system for allocating donated lungs skips over the patients who are most in need, say researchers. Using data provided by the United Network for Organ Sharing (UNOS), study author Mark J Russo, MD, MS, and colleagues at the University of Chicago and Columbia University found that donor lungs were routinely allocated to less urgent, local candidates even when there were patients within the region but outside the local donor service who were in much greater need. Among the ...]]> http://www.medindia.net/news/state-of-lung-transplantation-system-96884-1.htm