http://www.medindia.net/healthnews/combination-therapy-for-high-blood-pressure-news.asp Medindia largest health website in india. en-us Copyright 2013. All Rights Reserved. Wed, 19 Jun 2013 22:54:08 GMT http://www.medindia.net/news/lifestyle-factors-lack-of-awareness-key-reasons-behind-rise-of-hypertension-in-europe-120570-1.htm The European Society of Hypertension (ESH) and the European Society of Cardiology (ESC) have issued new guidelines for reducing the risk of hypertension and have identified lack of awareness among both patients and physicians, lifestyle factors, healthcare structural deficiencies and hesitancy in initiating and intensifying drug treatment as the key reasons for the increasing problem of high blood pressure in Europe. The Guidelines, which recommend several significant changes to hypertension ...]]> http://www.medindia.net/news/lifestyle-factors-lack-of-awareness-key-reasons-behind-rise-of-hypertension-in-europe-120570-1.htm http://www.medindia.net/news/volunteer-work-halves-risk-of-hypertension-in-older-adults-120507-1.htm A new study published in the journal Psychology and Aging reveals that older adults who do volunteer work can almost halve their risk of hypertension. The study was conducted by researchers at Carnegie Mellon University who followed more than 1,150 adults between 51 and 91 years of age in the United States. The participants were initially interviewed by the researchers in 2006 and were followed up once again in 2010 with the researchers asking questions about the participants' volunteerism and ...]]> http://www.medindia.net/news/volunteer-work-halves-risk-of-hypertension-in-older-adults-120507-1.htm http://www.medindia.net/news/citing-pill-mixup-france-recalls-diuretic-drug-120314-1.htm A diuretic used to control high blood pressure was recalled by the health regulator in France after some packets of the drug were found to contain sleeping pills. Stressing this was a precautionary measure, the ANSM regulatory agency urged people to return all boxes of Furosemide Teva 40 mg to their pharmacists. The agency suspended sales of two batches of the drug last Friday after a pharmacist reported sleepiness in a patient. Prosecutors opened a probe the following day after the ...]]> http://www.medindia.net/news/citing-pill-mixup-france-recalls-diuretic-drug-120314-1.htm http://www.medindia.net/news/patients-with-type-2-diabetes-or-hypertension-must-be-evaluated-for-sleep-apnea-american-academy-of-sleep-medicine-120087-1.htm Anyone with Type 2 diabetes or hypertension is being advised by the American Academy of Sleep Medicine (AASM) to be evaluated for sleep apnea by a board-certified sleep medicine physician. The recommendation comes as the group of international clinicians and researchers meets in Baltimore for SLEEP 2013, the foremost gathering of sleep experts annually. Overwhelming clinical evidence has shown that patients suffering from two very common illnesses - Type 2 diabetes and hypertension - are at ...]]> http://www.medindia.net/news/patients-with-type-2-diabetes-or-hypertension-must-be-evaluated-for-sleep-apnea-american-academy-of-sleep-medicine-120087-1.htm http://www.medindia.net/news/yoga-may-help-ease-hypertension-119772-1.htm Yoga could help decrease blood pressure in people with hypertension, says study. "So far it looks very promising that yoga might be a useful therapy for patients with mild-to-moderate hypertension who want to avoid using medication," study researcher Dr. Debbie Cohen, M.D., of the University of Pennsylvania, told MedPage Today. "This could also be used as an adjunct to other lifestyle modifications," she said. The study included 120 people with an average age of 50, 58 of whom completed the study....]]> http://www.medindia.net/news/yoga-may-help-ease-hypertension-119772-1.htm http://www.medindia.net/news/link-between-hypertension-and-better-quality-of-life-identified-118335-1.htm Teenagers with high blood pressure have less distress and enjoy a higher quality of life than those with normal blood pressure, says study published in iPsychosomatic Medicine: Journal of Biobehavioral Medicine. /i "This is the first report linking elevated blood pressure to quality of life and psychosocial adaptation in a large epidemiological study of adolescents," according to the report by Dr Angela Berendes of University of Gottingen, Germany, and colleagues. The authors speculate ...]]> http://www.medindia.net/news/link-between-hypertension-and-better-quality-of-life-identified-118335-1.htm http://www.medindia.net/news/researchers-suggest-new-drug-combination-therapy-to-treat-leukemia-117734-1.htm A new, pre-clinical study by researchers suggests that a novel drug combination could lead to profound leukemia cell death by disrupting the function of two major pro-survival proteins. The study took place at Virginia Commonwealth University Massey Cancer Center. The effectiveness of the therapy lies in its ability to target a pro-survival cell signaling pathway known as PI3K/AKT/mTOR, upon which the leukemia cells have become dependent. In the study, published in the journal iCancer ...]]> http://www.medindia.net/news/researchers-suggest-new-drug-combination-therapy-to-treat-leukemia-117734-1.htm http://www.medindia.net/news/who-says-hypertension-kills-15-million-each-year-in-south-east-asia-116995-1.htm In South-east Asia, nearly 1.5 million people die every year due to high blood pressure, a World Health Organisation (WHO) statement said. "High blood pressure or hypertension is the leading risk factor for deaths claiming 1.5 million lives each year. One in three adults has high blood pressure. Males have a slightly higher prevalence of high blood pressure than females in almost all countries," the statement said. WHO's theme for this year's World Health Day (April 7) is hypertension, or high blood pressure....]]> http://www.medindia.net/news/who-says-hypertension-kills-15-million-each-year-in-south-east-asia-116995-1.htm http://www.medindia.net/news/huge-disparities-in-hypertension-seen-across-us-counties-says-study-116912-1.htm One in five Americans are unaware that they are at an increased risk for high blood pressure, says recent study. In the first ever analysis of awareness, treatment, and control of hypertension for every county, the Institute for Health Metrics and Evaluation (IHME) at the University of Washington revealed significant differences across the US. The study found the largest burden of hypertension in the southeast, the lowest prevalence in Colorado, and differences among genders, ethnic groups and geographies....]]> http://www.medindia.net/news/huge-disparities-in-hypertension-seen-across-us-counties-says-study-116912-1.htm http://www.medindia.net/news/hypertension-could-up-alzheimers-disease-risk-115990-1.htm Hypertension earlier in life may increase the risk of Alzheimer's disease, suggests study. Dr. Karen Rodrigue, assistant professor in the UT Dallas Center for Vital Longevity (CVL), was lead author on a study that looked at whether people with both hypertension and a common gene associated with risk of Alzheimer's disease (the APOE-4 gene carried by about 20 percent of the population) had more build-up of the brain plaque (amyloid protein) associated with Alzheimer's disease. Based ...]]> http://www.medindia.net/news/hypertension-could-up-alzheimers-disease-risk-115990-1.htm http://www.medindia.net/news/who-india-may-get-monitoring-framework-for-hypertension-115973-1.htm India is exploring the possibility of having a national monitoring framework to help check hypertension cases, a WHO official said here Thursday. The national monitoring framework will try and amalgamate suggestions of the global monitoring framework for hypertension which will be adopted next month, the WHO official, who did not wish to be named, told reporters on the sidelines of workshop here. Officials of the health ministry met WHO officials and decided to explore the possibility of such a mechanism, she said....]]> http://www.medindia.net/news/who-india-may-get-monitoring-framework-for-hypertension-115973-1.htm http://www.medindia.net/news/combination-therapy-provides-similar-clinical-benefit-as-single-drug-treatment-in-ms-research-115774-1.htm According to an international research team, people with multiple sclerosis (MS) who were treated with combination therapy did not see significant clinical benefit over those treated with single drug therapy, but combination therapy did reduce the development of new lesions. The research team was led by The Mount Sinai Medical Center. The findings, part of the largest-ever MS trial sponsored by the National Institutes of Health, are published in the March 11 issue of iAnnals of Neurology/i....]]> http://www.medindia.net/news/combination-therapy-provides-similar-clinical-benefit-as-single-drug-treatment-in-ms-research-115774-1.htm http://www.medindia.net/news/risk-of-death-or-rehospitalization-not-reduced-by-combination-therapy-for-heart-failure-115748-1.htm Combination therapy is thought to help patients with heart failure avoid the risk of heart-related death or of rehospitilization. However a new study indicates otherwise. Among patients hospitalized for heart failure (HF) with reduced left ventricular ejection fraction (LVEF; a measure of how well the left ventricle of the heart pumps with each contraction), initiation of the medication aliskiren in addition to standard therapy did not reduce cardiovascular death or HF rehospitalization at 6 ...]]> http://www.medindia.net/news/risk-of-death-or-rehospitalization-not-reduced-by-combination-therapy-for-heart-failure-115748-1.htm http://www.medindia.net/news/researchers-novel-combination-therapy-shuts-down-escape-route-killing-glioblastoma-tumor-cells-115080-1.htm Glioblastoma is the most common and lethal form of brain tumor in adults. It is challenging to treat because the tumors rapidly become resistant to therapy. As cancer researchers are learning more about the causes of tumor cell growth and drug resistance, they are discovering molecular pathways that might lead to new targeted therapies to potentially treat this deadly cancer. Scientists at the Ludwig Institute for Cancer Research in San Diego worked collaboratively across the laboratories of Drs....]]> http://www.medindia.net/news/researchers-novel-combination-therapy-shuts-down-escape-route-killing-glioblastoma-tumor-cells-115080-1.htm http://www.medindia.net/news/hypertension-in-pregnancy-may-signal-heart-disease-risk-114188-1.htm High blood pressure during pregnancy may be a risk factor for heart disease later in life, states study published in Circulation. "All of the later life risks were similar in pregnant women who could otherwise be considered low-risk - those who were young, normal weight, non-smokers, with no diabetes during pregnancy," said Tuija Mannisto, M.D., Ph.D., lead author of the study and a postdoctoral fellow at the National Institutes of Health, Eunice Kennedy Shriver National Institute of ...]]> http://www.medindia.net/news/hypertension-in-pregnancy-may-signal-heart-disease-risk-114188-1.htm http://www.medindia.net/news/hypertension-during-pregnancy-ups-kidney-disease-risk-113266-1.htm Hypertensive disorders in pregnancy increase the risk of chronic kidney disease and end-stage renal disease, finds study published in CMAJ. "We found that women with hypertensive disorders during pregnancy were at higher risk of end-stage renal disease than women without complicated pregnancies," writes Dr. I-Kuan Wang, Division of Nephrology, China Medical University Hospital, Taichung, Taiwan, with co-authors. Hypertensive disorders such as gestational hypertension and preeclampsia in ...]]> http://www.medindia.net/news/hypertension-during-pregnancy-ups-kidney-disease-risk-113266-1.htm http://www.medindia.net/news/avastin-shows-promise-in-treating-deadly-brain-cancer-as-part-of-combination-therapy-110258-1.htm Phase III clinical trials conducted by Roche revealed that combining Avastin with radiation and temozolomide chemotherapy could slow down the progression of cancer in patients who are newly diagnosed with glioblastoma. According to the results from the AVAglio study, providing a combination therapy of Avastin, radiation and temozolomide chemotherapy for over a six week period followed Avastin and temozolomide for up to six cycles after a four week break and then giving Avastin alone reduced the ...]]> http://www.medindia.net/news/avastin-shows-promise-in-treating-deadly-brain-cancer-as-part-of-combination-therapy-110258-1.htm http://www.medindia.net/news/hospital-admissions-and-deaths-due-to-pulmonary-hypertension-increased-in-the-last-decade-109016-1.htm American researchers have found that the number of hospital admissions and deaths due to pulmonary hypertension in the US has increased over the last decade. A research team from Howard University Hospital, Washington, DC, examined multiple cause of death mortality data from the National Vital Statistics System and hospital discharge data from the National Hospital Discharge Survey for 1999-2009. Results showed that since 1999, the number of deaths and hospitalizations, as well as death rates ...]]> http://www.medindia.net/news/hospital-admissions-and-deaths-due-to-pulmonary-hypertension-increased-in-the-last-decade-109016-1.htm http://www.medindia.net/news/combination-therapy-may-lead-to-greater-disease-burden-in-pah-patients-108929-1.htm In patients with pulmonary arterial hypertension (PAH) combination therapy with intravenous PG12 may lead to greater disease burden, finds study. Researchers from Massachusetts General Hospital and Novartis Pharma AG in Switzerland performed statistical tests on 446 patients with PAH, of which (a) 337 were receiving monotherapy; (b) 88 were receiving non-IV PGI2 combination therapy; and (c) 21 were receiving IV PGI2 combination therapy. Results showed that pulmonary vascular resistance, mean ...]]> http://www.medindia.net/news/combination-therapy-may-lead-to-greater-disease-burden-in-pah-patients-108929-1.htm http://www.medindia.net/news/chronic-kidney-disease-warning-sign-independent-of-hypertension-or-diabetes-107562-1.htm In patients without hypertension or diabetes, chronic kidney disease can be a strong indicator of the risk of death and end-stage renal disease (ESRD), states study. Both hypertension and diabetes are common conditions with chronic kidney disease with hypertension being the most prevalent. The studies were released online in advance of publication in iThe Lancet/i. Chronic kidney disease affects 10 to 16 percent of all adults in Asia, Europe, Australia and the United States. Kidney ...]]> http://www.medindia.net/news/chronic-kidney-disease-warning-sign-independent-of-hypertension-or-diabetes-107562-1.htm http://www.medindia.net/news/study-links-poor-sleep-quality-to-resistant-hypertension-107401-1.htm Insomnia can have dire consequences on people who already have been suffering from high blood pressure, finds a new study. Researchers studied the sleeping patterns of 234 people with high blood pressure. Most participants slept six or fewer hours, and those who also reported poor sleep quality were twice as likely to have resistant hypertension as those who slept well. Your blood pressure is considered resistant if you are taking three or more blood pressure medications but still have a blood pressure reading higher than 140/90 mmHg....]]> http://www.medindia.net/news/study-links-poor-sleep-quality-to-resistant-hypertension-107401-1.htm http://www.medindia.net/news/renal-artery-stent-helps-maintain-normal-blood-pressure-levels-in-renovascular-hypertension-patients-106421-1.htm Fitting a renal artery stent in uncontrolled renovascular hypertension patients could lead to a significant improvement of their blood pressure levels, a new study reveals. The multicenter HERCULES trial, evaluating the safety and effectiveness of the RX Herculink Elite Stent, found that patients with higher blood pressure levels at baseline had the most dramatic reduction in blood pressure following intervention. Trial details appear in iCatheterization and Cardiovascular Interventions/i, ...]]> http://www.medindia.net/news/renal-artery-stent-helps-maintain-normal-blood-pressure-levels-in-renovascular-hypertension-patients-106421-1.htm http://www.medindia.net/news/renal-sympathetic-denervation-may-improve-quality-of-life-in-resistant-hypertension-patients-106201-1.htm A new study presented by Saarland University Hospital's Dr Denise Fischer at ESC Congress 2012 reveals that patients with resistant hypertension can improve their anxiety, depression, quality of life and stress levels through renal sympathetic denervation. Arterial hypertension is often associated with several psychological comorbidities, such as anxiety and panic disorders, leading to impaired quality of life. Catheter-based renal sympathetic denervation (RDN) is a novel treatment option for ...]]> http://www.medindia.net/news/renal-sympathetic-denervation-may-improve-quality-of-life-in-resistant-hypertension-patients-106201-1.htm http://www.medindia.net/news/healthy-lifestyle-cuts-hypertension-risk-106140-1.htm Healthy behaviors reduce the risk of hypertension by two thirds, reveals recent study. According to the World Health Organization, hypertension is the leading cause of mortality in the world, contributing annually to over 7 million deaths (about 15% of all deaths). Therefore, prevention of hypertension is essential to improving health and preventing morbidity and mortality, both in developing and developed countries. The purpose of this study was to examine whether five major cardiovascular ...]]> http://www.medindia.net/news/healthy-lifestyle-cuts-hypertension-risk-106140-1.htm http://www.medindia.net/news/researchers-identify-new-genetic-target-for-diuretic-therapy-104870-1.htm A novel genetic target for diuretic therapy has been discovered by University of Cincinnati researchers. These results, being presented in the July 30 advance online edition of the journal iProceedings of the National Academy of Sciences/i (iPNAS/i), may lead to the first new diuretic therapy in 25 years and could help patients who experience diuretic resistance. Manoocher Soleimani, MD, professor and chief in the division of nephrology and hypertension, says the role of diuretics ...]]> http://www.medindia.net/news/researchers-identify-new-genetic-target-for-diuretic-therapy-104870-1.htm http://www.medindia.net/news/study-examines-use-of-diagnostic-tests-in-adolescents-with-hypertension-104672-1.htm Recommended diagnostic tests for hypertension in adolescents, including renal ultrasonography and echocardiograms, are being poorly used, a new study among teenagers with Michigan Medicaid program and published in Archives of Pediatrics (and) Adolescent Medicine reveals. Hypertension is a growing problem for adolescents because of the association between obesity and hypertension. Current pediatric guidelines recommend laboratory tests and renal ultrasonography for all pediatric patients with hypertension to rule out renal (kidney) disease....]]> http://www.medindia.net/news/study-examines-use-of-diagnostic-tests-in-adolescents-with-hypertension-104672-1.htm http://www.medindia.net/news/new-line-of-approach-for-combination-therapy-against-melanoma-identified-104537-1.htm Researchers have found a new line of approach for combination treatment against aggressive skin cancers. Their research offers a new angle for the development of medication and confirms that combination therapies - including those using the recently developed BRAF inhibitors - hold the promise of further improvement of the clinical response to a treatment. This study was published in the authoritative journal iNature Medicine/i and will undoubtedly be followed with interest by the pharmaceutical industry....]]> http://www.medindia.net/news/new-line-of-approach-for-combination-therapy-against-melanoma-identified-104537-1.htm http://www.medindia.net/news/potential-combination-therapy-for-breast-cancer-identified-103609-1.htm Researchers have identified an effective combination therapy for breast cancer cells. The findings, published in the July 2012 issue of iAnticancer Research/i, raise the possibility of using this type of combination therapy for different forms of breast cancer, including those that develop resistance to chemotherapy and other treatments. The study was led by researchers at the Boston University Cancer Center. Sibaji Sarkar, PhD, adjunct instructor of medicine at BUSM, is the study's corresponding author....]]> http://www.medindia.net/news/potential-combination-therapy-for-breast-cancer-identified-103609-1.htm http://www.medindia.net/news/link-between-insomnia-and-hypertension-102335-1.htm Insomniacs are at an increased risk of developing hypertension, claims study. Researchers at the Henry Ford Center for Sleep Disorders, Detroit, found that the prevalence of hypertension was greater in insomniacs compared to normal sleepers. "The cause of hypertension in insomniacs is due to the number of times the individual wakes during the night as well as their sleep latency - the length of time it takes to accomplish the transition from full wakefulness to sleep," Christopher Drake, lead author of this study, said....]]> http://www.medindia.net/news/link-between-insomnia-and-hypertension-102335-1.htm http://www.medindia.net/news/exercise-may-reduce-hypertension-risk-101304-1.htm Moderate exercise and increased cardiovascular fitness may help reduce risk of developing hypertension in people with family history, reveals study published in Hypertension. In a study of more than 6,000 people, those who had a parent with high blood pressure but were highly fit had a 34 percent lower risk of developing high blood pressure themselves, compared to those with a low-fitness level who had the same parental history. "Understanding the roles that family history and fitness ...]]> http://www.medindia.net/news/exercise-may-reduce-hypertension-risk-101304-1.htm http://www.medindia.net/news/combination-therapy-best-way-to-control-diabetes-in-children-100734-1.htm Researchers at University of Colorado have revealed that using a combination of two drugs instead of just one could be an effective way of keeping the blood sugar levels within normal range in children. The researchers said that combining metformin with Avandia, or rosiglitazone, could be more effective in reducing blood sugar levels compared to using metformin alone. However researchers added that they do not recommend using Avandia as it has been linked to increased risk of heart attacks. Around ...]]> http://www.medindia.net/news/combination-therapy-best-way-to-control-diabetes-in-children-100734-1.htm http://www.medindia.net/news/administration-of-second-generation-drug-for-hypertension-aids-heart-function-independent-of-blood-pressure-effect-100494-1.htm All over the world heart failure is the frequent cause of death, typically the result of chronic high blood pressure, also known as hypertension. As a result, research efforts have focused on an array of approaches aimed at preventing and treating high blood pressure. Recently, Japanese researchers examined the utility of an anti-hypertensive drug, moxonidine, which acts on the imidazoline receptors in the cardiovascular center of the brainstem. They found, using an animal model, that the drug ...]]> http://www.medindia.net/news/administration-of-second-generation-drug-for-hypertension-aids-heart-function-independent-of-blood-pressure-effect-100494-1.htm http://www.medindia.net/news/hypertension-study-treatment-with-raas-inhibitors-saves-lives-proven-100308-1.htm An ACE inhibitor employed treatment for lowering high blood pressure demonstrated a major mortality decline in patients with a high incidence of hypertension, states a report published in the iEuropean Heart Journal/i, the flagship journal of the European Society of Cardiology. In the study, 20 different trials including nearly 160,000 randomly selected patients with high blood pressure were treated with renin-angiotensin-aldosterone system (RAAS) inhibitors or control treatment, such as ...]]> http://www.medindia.net/news/hypertension-study-treatment-with-raas-inhibitors-saves-lives-proven-100308-1.htm http://www.medindia.net/news/combination-therapy-may-help-patients-with-lung-cancer-who-are-ineligible-for-bevacizumab-99900-1.htm New research indicates that patients with non-small cell lung cancer ineligible for treatment with bevacizumab may be helped by a combination of nab-paclitaxel and carboplatin. The data was presented at the AACR Annual Meeting 2012. "The combination of carboplatin and nab-paclitaxel demonstrates promising efficacy with tolerable toxicity in patients with non-small cell lung cancer (NSCLC) ineligible for therapy with bevacizumab," said Gregory A. Otterson, M.D., professor of internal medicine, ...]]> http://www.medindia.net/news/combination-therapy-may-help-patients-with-lung-cancer-who-are-ineligible-for-bevacizumab-99900-1.htm http://www.medindia.net/news/combination-therapy-may-not-help-in-treatment-of-endocrine-resistant-breast-cancer-cells-99744-1.htm Researchers at Georgetown Lombardi Comprehensive Cancer Center have warned that a new class of agents known as c-Src inhibitors should not be used in combination with estrogen to treat endocrine resistant breast cancer. That's because their new study, being reported at the American Association for Cancer Research (AACR) Annual Meeting 2012, shows that using estrogen and a c-Src inhibitor, PP2, cancel each other out. The benefit once seen in using estrogen was gone once PP2, an inhibitor of the ...]]> http://www.medindia.net/news/combination-therapy-may-not-help-in-treatment-of-endocrine-resistant-breast-cancer-cells-99744-1.htm http://www.medindia.net/news/antidepressant-use-may-boost-hypertension-in-pregnant-women-study-99154-1.htm Use of serotonin re-uptake inhibitor (SSRI) antidepressants may cause pregnancy hypertension, warns study. But a causal link has not been established and researchers behind the study said that pregnant women should not stop taking their prescribed medication; instead they should seek a consultation with their doctor if they are concerned. Pregnancy hypertension is sometimes linked with pre-eclampsia, a serious condition that can harm pregnant women and their unborn babies. Out of ...]]> http://www.medindia.net/news/antidepressant-use-may-boost-hypertension-in-pregnant-women-study-99154-1.htm http://www.medindia.net/news/new-combination-therapy-possible-via-molecules-role-in-cancer-98343-1.htm A molecule found at high levels in cancer cells protects them from the "cell-suicide" that is usually triggered by chemotherapy or radiation, according to researchers at the University of Illinois at Chicago College of Medicine. The study, published online in the journal IPLoS One/I on Feb. 29, suggests that two common cancer-fighting strategies may have "tremendous synergy" if used in combination, says Andrei Gartel, UIC associate professor of biochemistry and molecular genetics and medicine and principal investigator on the study....]]> http://www.medindia.net/news/new-combination-therapy-possible-via-molecules-role-in-cancer-98343-1.htm http://www.medindia.net/news/combination-therapy-ups-gemcitabine-activity-study-98147-1.htm Combination of gemcitabine and nab-paclitaxel works in patients with pancreatic cancer, shows study published in ICancer Discovery/I. David Tuveson, M.D., Ph.D., a professor of pancreatic cancer medicine at the University of Cambridge, utilized a laboratory model to test the combination of gemcitabine and nab-paclitaxel in pancreatic cancer. "The combination has shown promise in an early clinical trial, and clinical results from a pivotal phase III trial will be reported in 2013," said Tuveson....]]> http://www.medindia.net/news/combination-therapy-ups-gemcitabine-activity-study-98147-1.htm http://www.medindia.net/news/Combination-Therapy-Benefits-Children-With-ADHD-95973-1.htm While pharmacologic agents have a proved effective in children with Attention-deficit/hyperactivity disorder (ADHD), some children have suboptimal response to a single pharmacologic agent. A recent study by Dr. Timothy E. Wilens and colleagues, published in the January 2012 issue of the IJournal of the American Academy of Child and Adolescent Psychiatry/I (JAACAP), is the first randomized placebo-controlled trial designed to assess efficacy and safety of guanfacine extended release (GXR) ...]]> http://www.medindia.net/news/Combination-Therapy-Benefits-Children-With-ADHD-95973-1.htm http://www.medindia.net/news/Novel-Combination-Therapy-For-Asthma-Found-To-Be-Safe-And-Fast-Acting-95969-1.htm The novel fixed-dose drug combination of mometasone furoate and formoterol fumarate (MF/F) may have the same efficacy as that of the commonly prescribed fluticasone propionate/salmeterol (FP/S) combination in the treatment of asthma. MF/F has a quicker onset of action compared with FP/S. bAsthma is a chronic inflammatory disease that causes the airways to swell and narrow. It /bbresults in recurrent coughing, chest tightness, wheezing, and breathlessness. /bMore than 300 million ...]]> http://www.medindia.net/news/Novel-Combination-Therapy-For-Asthma-Found-To-Be-Safe-And-Fast-Acting-95969-1.htm http://www.medindia.net/news/Hypertension-Treatment-in-People-With-Diabetes-95861-1.htm Middle-aged people diagnosed with diabetes and hypertension have time to learn how to control blood pressure without drugs, but not too much time, because as the delay gets longer, the damages multiply, shows study. The consequences of delaying effective hypertension treatment for up to a year were small-a two-day reduction in quality-adjusted life expectancy-according to a study by University of Chicago researchers published online for the iJournal of General Internal Medicine/i. A ...]]> http://www.medindia.net/news/Hypertension-Treatment-in-People-With-Diabetes-95861-1.htm http://www.medindia.net/news/Pollution-Ups-Diabetes-and-Hypertension-in-African-American-Women-95760-1.htm An increase in the incidence of type 2 diabetes and hypertension with cumulative levels of exposure to nitrogen oxides, was observed in a new study led by researchers from the Slone Epidemiology Center (SEC) at Boston University. The study, which appears online in the journal ICirculation/I, was led by Patricia Coogan, D.Sc., associate professor of epidemiology at the Boston University School of Public Health and the SEC. While it is well established that air pollution increases the ...]]> http://www.medindia.net/news/Pollution-Ups-Diabetes-and-Hypertension-in-African-American-Women-95760-1.htm http://www.medindia.net/news/Bristol-Myers-and-Johnson-Johnson-to-Study-Combination-Therapy-for-Hepatitis-C-94292-1.htm Bristol-Myers Squibb Co. will collaborate with a unit of Johnson (and) Johnson to study a potential combination therapy for chronic hepatitis C.The companies will test the potentially positive effects of combining Johnson (and) Johnson's drug TMC435 with Bristol-Myers Squibb's daclatasvir. The clinical trials will begin in the first half of 2012 and will include a combination of the two drugs, the drugs plus pegylated interferon and ribavirin, and the drugs plus ribavirin.The terms of their partnership were not disclosed....]]> http://www.medindia.net/news/Bristol-Myers-and-Johnson-Johnson-to-Study-Combination-Therapy-for-Hepatitis-C-94292-1.htm http://www.medindia.net/news/Hypertension-Cases-in-Canada-93808-1.htm By 2012/13 more than one-quarter of Canadians projected to have high blood pressure (hypertension), shows study in CMAJ (Canadian Medical Association Journal). Older women were more likely to be diagnosed with high blood pressure compared with men, and people in the Atlantic provinces had the highest rates of hypertension. Canadian researchers looked at data on 26 million adults aged 20 years and over between 1998 and 2007/08 to determine how common hypertension was in the population (prevalence) ...]]> http://www.medindia.net/news/Hypertension-Cases-in-Canada-93808-1.htm http://www.medindia.net/news/Clinical-Worsening-in-Pulmonary-Hypertension-can-be-Predicted-by-Heart-Rate-Recovery-93716-1.htm A new study says that heart rate recovery at one minute after a six-minute walking distance (6MWD) test is highly predictive of clinical worsening and time to clinical worsening in patients with idiopathic pulmonary arterial hypertension (IPAH). "Ours is the first study to show that heart rate recovery at one minute of rest (HRR1) following a 6MW test is a strong predictor of clinical worsening in IPAH patients," said Omar A. Minai, MD, staff physician in the Department of Pulmonary, Allergy, ...]]> http://www.medindia.net/news/Clinical-Worsening-in-Pulmonary-Hypertension-can-be-Predicted-by-Heart-Rate-Recovery-93716-1.htm http://www.medindia.net/news/Pregnant-Women-With-History-of-Hypertension-At-Depression-Risk-93656-1.htm Women with high blood pressure before pregnancy are at an increased risk of developing depression than those who develop pregnancy-related hypertension, finds a new study. "Depression during pregnancy is associated with postpartum depression, problems bonding with the baby, and overall, has a large and detrimental impact on both mom and baby," said lead author Wayne Katon, M.D., of the Department of Psychiatry and Behavioural Sciences at the University of Washington. The study looked at ...]]> http://www.medindia.net/news/Pregnant-Women-With-History-of-Hypertension-At-Depression-Risk-93656-1.htm http://www.medindia.net/news/In-Preclinical-Studies-Combination-Therapy-Shows-Potent-Tumor-Growth-Inhibition-93379-1.htm New research has revealed that combining the investigational agents REGN910 and aflibercept yielded statistically significant improvements in anti-tumor effects in animal models compared with either agent alone. The findings were presented at the AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics. "These preclinical findings suggest that combining REGN910 (SAR307746) and aflibercept in the clinic could be an attractive approach for future clinical research," said Alshad S....]]> http://www.medindia.net/news/In-Preclinical-Studies-Combination-Therapy-Shows-Potent-Tumor-Growth-Inhibition-93379-1.htm http://www.medindia.net/news/Lives-of-Those-With-Pulmonary-Hypertension-Being-Enhanced-by-LA-BioMeds-Dr-Ronald-Oudiz-92907-1.htm Research has indicated that a condition called pulmonary arterial hypertension (PAH) affects between 500-1,000 people each year. Furthermore, most of the patients are young women between the ages of 20 and 40. While the numbers may not seem significant, the disease itself has been a paradox for physician-researchers since in many cases, the causes of PAH remain unknown. As the month of November kicks off PH Awareness Month, Dr. Ronald Oudiz - lead investigator at the Los Angeles Biomedical ...]]> http://www.medindia.net/news/Lives-of-Those-With-Pulmonary-Hypertension-Being-Enhanced-by-LA-BioMeds-Dr-Ronald-Oudiz-92907-1.htm http://www.medindia.net/news/Hypertension-Increases-Risk-of-Birth-Defects-in-Babies-92196-1.htm Expectant mothers with hypertension must be aware that the condition can cause birth defects such as congenital heart disease in their children. Researchers also found that the risk of malformation and birth defects in children looms large even if expectant women took anti-hypertension medication. The risk is present because of the underlying condition of hypertension, researchers said. Earlier studies had indicated the risk of birth defects with some of the anti-hypertension drugs employed to regulate blood pressure in expectant mothers....]]> http://www.medindia.net/news/Hypertension-Increases-Risk-of-Birth-Defects-in-Babies-92196-1.htm http://www.medindia.net/news/Study-Explores-Use-of-Hypertension-Drugs-to-Treat-Dementia-92169-1.htm A new study explores if certain types of drugs used to treat high blood pressure, also called hypertension, might have beneficial effects in reducing the increasing number of new cases of Alzheimer's disease each year. Within the next 20 years it is expected the number of people with Alzheimer's disease (AD) will double from its current figure of half a million to one million. The team of researchers from the University of Bristol have looked at whether drugs already being used to treat hypertension, ...]]> http://www.medindia.net/news/Study-Explores-Use-of-Hypertension-Drugs-to-Treat-Dementia-92169-1.htm