http://www.medindia.net/healthnews/asbestosis-news.asp Medindia largest health website in india. en-us Copyright 2012. All Rights Reserved. Fri, 25 May 2012 04:19:24 GMT http://www.medindia.net/news/danger-detected-in-standard-treatment-for-a-grave-lung-disease-101644-1.htm Three drugs combined and administered globally as the standard of care for a grave lung disease is fatally life-threatening to people, and must be refrained from using together to treat the disease, called idiopathic pulmonary fibrosis, states the startling results of a rigorous independent study. The study, which will appear online May 20 in the iNew England Journal of Medicine/i to coincide with a presentation at the annual meeting of the American Thoracic Society, was conducted by IPF ...]]> http://www.medindia.net/news/danger-detected-in-standard-treatment-for-a-grave-lung-disease-101644-1.htm http://www.medindia.net/news/bared-to-tobacco-fumes-children-run-into-long-term-respiratory-complications-study-101643-1.htm Over three decades, researchers have cautioned of latent health risks linked to exposure to environmental tobacco smoke (ETS), mainly among children whose parents smoke. Now a new study conducted by researchers from the University of Arizona reports that those health risks persist well beyond childhood, independent of whether or not those individuals end up becoming smokers later in life. The study will be presented at the ATS 2012 International Conference in San Francisco. "This study ...]]> http://www.medindia.net/news/bared-to-tobacco-fumes-children-run-into-long-term-respiratory-complications-study-101643-1.htm http://www.medindia.net/news/tb-raises-lung-cancer-mortality-risk-in-elderly-101636-1.htm Elderly patients who have tuberculosis are at increased risk of dying from lung cancer, finds a new study. "There is a high incidence of both tuberculosis and lung cancer among the elderly in Hong Kong," said lead author Chi Chiu Leung, MBBS, consultant chest physician in the Tuberculosis and Chest Service of the Department of Health of Hong Kong. "In our prospective follow-up study of a cohort of 61,239 subjects aged 65 years or older, we found that active tuberculosis was an independent predictor ...]]> http://www.medindia.net/news/tb-raises-lung-cancer-mortality-risk-in-elderly-101636-1.htm http://www.medindia.net/news/molecular-biomarkers-in-tissue-and-lining-of-lungs-provide-another-technique-for-lung-cancer-screening-101478-1.htm Using the molecular biomarkers present in the tissue and fluid lining of the lungs may be another technique that can be used in lung cancer screening, according to a new study published in the Journal of Thoracic Oncology. Since the National Lung Screening Trial found that 96.4 percent of the positive CT screening results were false positive, scientists have been looking for ways to more accurately diagnose patients. This research focused on a way to determine if the nodules detected by the CT screening, are in fact malignant or benign....]]> http://www.medindia.net/news/molecular-biomarkers-in-tissue-and-lining-of-lungs-provide-another-technique-for-lung-cancer-screening-101478-1.htm http://www.medindia.net/news/lung-cancer-screening-via-video-assisted-thoracic-surgery-101444-1.htm Video assisted thoracic surgery (VATS) is a valuable tool in managing lesions detected in a lung cancer screening program, according to the most recent research released in June's iJournal of Thoracic Oncology/i. The primary objective of lung cancer screening with low dose computer tomography (CT) is to detect lung cancer at an early stage and thus amenable to a complete surgical resection, the only established cure for lung cancer. Lung cancer currently has no standard screening program ...]]> http://www.medindia.net/news/lung-cancer-screening-via-video-assisted-thoracic-surgery-101444-1.htm http://www.medindia.net/news/response-to-lung-cancer-therapy-probably-resolved-by-molecular-subtypes-and-genetic-alterations-101281-1.htm Cancer therapies aiming precise molecular subtypes of the disease grants physicians to customise treatment to a person's individual molecular profile. But scientists are finding that in many types of cancer the molecular subtypes are more varied than previously thought and contain further genetic alterations that can affect a patient's response to therapy. A UNC-led team of scientists has shown for the first time that lung cancer molecular subtypes correlate with distinct genetic alterations and with patient response to therapy....]]> http://www.medindia.net/news/response-to-lung-cancer-therapy-probably-resolved-by-molecular-subtypes-and-genetic-alterations-101281-1.htm http://www.medindia.net/news/persistent-cough-could-be-a-sign-of-lung-cancer-100989-1.htm Continuous cough could signal lung cancer, warns new government advertising drive. The campaign, which is being run in TV, radio, print and online media, recommends people with coughs lasting three weeks visit their GP. Research has shown that the public are much more aware that lumps and bleeding are warning signs of cancer than a cough, but the ads make clear persistent coughs should also raise alarm bells. The push is being backed by celebrities including comedian and actor ...]]> http://www.medindia.net/news/persistent-cough-could-be-a-sign-of-lung-cancer-100989-1.htm http://www.medindia.net/news/lung-cancer-risk-influenced-by-genetic-variants-and-tobacco-exposure-100646-1.htm Lung cancer risk is largely mediated by level of tobacco exposure as there is an association between the rs1051730-rs16969968 genotype and objective measures of tobacco exposure. These are the findings of a study published April 25 in the iJournal of the National Cancer Institute/i. The rs1051730-rs16969968 genotype is known to be associated with heaviness of smoking, lung cancer risk, and other smoking-related outcomes. Prior studies have generally depended on self-reported smoking behavior, ...]]> http://www.medindia.net/news/lung-cancer-risk-influenced-by-genetic-variants-and-tobacco-exposure-100646-1.htm http://www.medindia.net/news/gene-critical-to-development-and-spread-of-lung-cancer-identified-100546-1.htm Researchers have discovered a single gene that promotes initial development of most common form of lung cancer. The study, published in the journal on April 24, shows that MMP-10 is a growth factor secreted and then used by cancer stem-like cells to keep themselves vital. These cells then drive lung cancer and its spread, and are notoriously immune to conventional treatment. The findings raise hope for a possible treatment for non-small cell lung cancer, the leading cause of U.S....]]> http://www.medindia.net/news/gene-critical-to-development-and-spread-of-lung-cancer-identified-100546-1.htm http://www.medindia.net/news/opioids-improve-quality-of-life-in-obstructive-lung-disease-patients-100545-1.htm Opioids effective in relieving shortness of breath and thereby improving quality of life in chronic obstructive pulmonary disease (COPD) patients, reveals research published in Canadian Medical Association Journal. The prevalence of COPD in Canada is increasing, and shortness of breath (dyspnea) is a major symptom that is difficult to treat and can result in fear, anxiety and a decreased quality of life. Although opioids are often used to treat pain and dyspnea associated with malignant diseases, they are underused in COPD treatment....]]> http://www.medindia.net/news/opioids-improve-quality-of-life-in-obstructive-lung-disease-patients-100545-1.htm http://www.medindia.net/news/study-says-hispanic-lung-cancer-patients-tend-to-live-longer-than-blacks-and-whites-100519-1.htm Hispanic lung cancer patients live longer than white or black patients, shows study published in Cancer. Most studies that look at ethnic and racial disparities in lung cancer compare black patients with whites. To see how Hispanics compare with other ethnicities with regards to survival after a lung cancer diagnosis, Ali Saeed, an MD/PhD candidate, and Brian Lally, MD, of the University of Miami Miller School of Medicine, led a team that analyzed patient information from the Survival, ...]]> http://www.medindia.net/news/study-says-hispanic-lung-cancer-patients-tend-to-live-longer-than-blacks-and-whites-100519-1.htm http://www.medindia.net/news/risk-of-relapse-in-lung-cancer-patients-may-be-identified-by-gene-signature-100393-1.htm In a study presented at the 3rd European Lung Cancer Conference in Geneva, Spanish researchers revealed that they have identified a new genetic signature that could help doctors assess whether a patient with early stage lung cancer is at a greater risk of suffering from a relapse after surgery. Their work also opens new avenues for immunotherapy for lung cancer. Non-small cell lung cancer is a disease that is often not diagnosed until it has grown and spread throughout the body. Even those ...]]> http://www.medindia.net/news/risk-of-relapse-in-lung-cancer-patients-may-be-identified-by-gene-signature-100393-1.htm http://www.medindia.net/news/use-of-erlotinib-in-advanced-non-small-cell-lung-cancer-may-be-guided-by-new-analysis-100392-1.htm Researchers have revealed that patients with advanced non-small cell lung cancer should only receive treatment with the drug erlotinib before receiving standard chemotherapy if their tumor is known to harbor EGFR mutations. The study was presented at the 3rd European Lung Cancer Conference in Geneva, Switzerland. The results of biomarker analyses of a recently reported clinical trial confirm that patients with unknown or negative mutation status should be treated with the standard chemotherapy first, they say....]]> http://www.medindia.net/news/use-of-erlotinib-in-advanced-non-small-cell-lung-cancer-may-be-guided-by-new-analysis-100392-1.htm http://www.medindia.net/news/new-studies-to-be-presented-at-lung-cancer-conference-in-geneva-100366-1.htm The 3rd European Lung Cancer Conference in Geneva will see experts present a number of studies that can help doctors to customize lung cancer treatment depending on the characteristics of the individual patients. "A major goal of lung cancer treatment is to tailor the treatment to the individual," says Dr Fiona Blackhall from The Christie NHS Foundation Trust in Manchester, UK. "The studies that will be presented at ELCC 2012 are important practical steps to achieving this in the clinic. Methods ...]]> http://www.medindia.net/news/new-studies-to-be-presented-at-lung-cancer-conference-in-geneva-100366-1.htm http://www.medindia.net/news/new-drug-to-reduce-risk-of-respiratory-viral-infections-100324-1.htm Researchers at University of Southampton are currently developing a new drug that could reduce the risk of respiratory viral infections that lead to worsening of symptoms among asthmatics. Recent figures have revealed that over 80 percent of asthma-related emergency visits are due to respiratory viral infections, such as common cold, which spread to the lungs and cause worsening of asthma attacks. Researchers are currently conducting clinical trials of the drug, known as SNG001, which they hope ...]]> http://www.medindia.net/news/new-drug-to-reduce-risk-of-respiratory-viral-infections-100324-1.htm http://www.medindia.net/news/drug-added-to-customary-chemotherapy-does-not-offer-survival-benefit-for-older-lung-cancer-patients-100309-1.htm Drug bevacizumab (Avastin) added to the standard chemotherapy regimen for non-small cell lung cancer (NSCLC), an approach authorised by the FDA in 2006, did not lead to notably boost survival rates for patients over the age of 65 enrolled in Medicare, state findings by researchers of a new study by Dana-Farber Cancer Institute. The study is being published in the April 18 iJournal of the American Medical Association/i, a these issue on comparative effectiveness research. "Effectiveness ...]]> http://www.medindia.net/news/drug-added-to-customary-chemotherapy-does-not-offer-survival-benefit-for-older-lung-cancer-patients-100309-1.htm http://www.medindia.net/news/research-into-follow-up-care-for-lung-cancer-vital-100196-1.htm A new study published in the International Association for the Study of Lung Cancer's (IASLC) Journal of Thoracic Oncology underlines the importance of looking into all aspects of follow-up care provided to patients with lung cancer. After searching the published literature and databases, researchers analyzed four studies and could not determine that one method was preferred over another. "Thus it is clear that more prospective research is needed in this area, ideally in the form of well-designed ...]]> http://www.medindia.net/news/research-into-follow-up-care-for-lung-cancer-vital-100196-1.htm http://www.medindia.net/news/genetic-variations-linked-with-risk-of-lung-cancer-100177-1.htm A new study published in the Journal of Thoracic Oncology has confirmed that some genetic variations increase the risk of lung cancer. Researchers looked at the genetics of 716 Japanese patients with lung cancer and 716 without. They found, "the variants rs12914385, rs1317286 and rs931794 localized to the CHRNA5-CHRNA3-CHRNB4 cluster on chromosome 15q25 modified the impact of cigarette smoking on lung cancer risk, but showed no statistically significant major effect on the risk of lung cancer....]]> http://www.medindia.net/news/genetic-variations-linked-with-risk-of-lung-cancer-100177-1.htm http://www.medindia.net/news/proteomic-biomarker-analysis-of-lung-cancer-tissue-samples-100159-1.htm By means of proteomic assay technology researchers identified significant expression changes in lung cancer tissue samples. "Early detection of NSCLC can dramatically improve the prognosis for patients with the disease, as has been shown recently through the use of CT-scans in a high-risk population of heavy smokers," said Sheri Wilcox, Ph.D., Director of Discovery Sciences at SomaLogic. "However, this approach has a high false-positive rate, which can result in overdiagnosis and unnecessary treatment....]]> http://www.medindia.net/news/proteomic-biomarker-analysis-of-lung-cancer-tissue-samples-100159-1.htm http://www.medindia.net/news/combination-therapy-may-help-patients-with-lung-cancer-who-are-ineligible-for-bevacizumab-99900-1.htm New research indicates that patients with non-small cell lung cancer ineligible for treatment with bevacizumab may be helped by a combination of nab-paclitaxel and carboplatin. The data was presented at the AACR Annual Meeting 2012. "The combination of carboplatin and nab-paclitaxel demonstrates promising efficacy with tolerable toxicity in patients with non-small cell lung cancer (NSCLC) ineligible for therapy with bevacizumab," said Gregory A. Otterson, M.D., professor of internal medicine, ...]]> http://www.medindia.net/news/combination-therapy-may-help-patients-with-lung-cancer-who-are-ineligible-for-bevacizumab-99900-1.htm http://www.medindia.net/news/treatment-with-new-lung-cancer-enhanced-with-drug-clinical-insight-99889-1.htm Men go through a distinct fall in their testosterone levels when taking a targeted therapy to control a particular type of lung cancer. That's according to a University of Colorado Cancer Center study published in the April issue of ICancer,/I the official journal of the American Cancer Society. Investigators at CU Cancer Center looked at the hormone levels in men with anaplastic lymphoma kinase (ALK) positive advanced non-small cell lung cancer (NSCLC) taking crizotinib, after a 35-year-old ...]]> http://www.medindia.net/news/treatment-with-new-lung-cancer-enhanced-with-drug-clinical-insight-99889-1.htm http://www.medindia.net/news/lung-cancer-affects-many-shanghai-women-99757-1.htm Media reports indicate that lung cancer is affecting more women than men in the Chinese metropolis of Shanghai. The number of women with lung cancer rose 38.4 percent over the past five years while the growth rate for men was 16.9 percent, the Shanghai Daily reported. However, men were still far more likely to get the deadly disease. The incidence of lung cancer among men was 88 per 100,000 people and 30 among women. An expert said the rise in female cases has resulted due to many young women taking up smoking....]]> http://www.medindia.net/news/lung-cancer-affects-many-shanghai-women-99757-1.htm http://www.medindia.net/news/heart-disease-risk-for-asbestos-workers-99665-1.htm A British study has revealed that asbestos workers also run a greater danger of heart disease and stroke apart from the already known risk of cancer. Researchers looked into more than 15,000 deaths that occurred among nearly 99,000 workers in the British asbestos industry between 1971 and 2005. Almost 4,200 deaths were caused by heart disease and more than 1,000 by a stroke, particularly among women. Male asbestos workers were 63 percent likelier to die of a stroke and 39 percent likelier ...]]> http://www.medindia.net/news/heart-disease-risk-for-asbestos-workers-99665-1.htm http://www.medindia.net/news/ct-scans-more-effective-than-traditional-methods-in-detecting-lung-cancer-99527-1.htm CT scans are more effective in detecting lung cancer, than the traditional methods, at identifying aggressive lung cancers in their most treatable stages. The data, published online March 27 in the journal IRadiology/I, demonstrate that lung cancers found through annual CT screening are similar to those found in routine practice, both in terms of tumor growth rates and cell-type distribution. In fact, the report showed that 79 percent of the cases diagnosed through annual repeat CT scans ...]]> http://www.medindia.net/news/ct-scans-more-effective-than-traditional-methods-in-detecting-lung-cancer-99527-1.htm http://www.medindia.net/news/stigma-ups-depression-in-lung-cancer-patients-study-99313-1.htm Researchers link stigma to depression among patients with lung cancer, reveals study. Researchers at Moffitt Cancer Center in Tampa, Fla., found that these factors may contribute to depression at rates higher than experienced by patients with other kinds of cancer. "To the best of our knowledge, this is the first study to examine the relationship of perceived stigma to depressive symptomology in lung cancer patients," said study co-author Paul B. Jacobsen, Ph.D., Moffitt's associate center director for Population Sciences....]]> http://www.medindia.net/news/stigma-ups-depression-in-lung-cancer-patients-study-99313-1.htm http://www.medindia.net/news/rnai-could-enhance-lung-cancer-treatment-99150-1.htm Blocking the production of epidermal growth factor receptor using RNAi could enhance the effect of tyrosine kinase inhibitors on lung cancer cell death, shows study published in BMC Medicine. There are 1.2 million new cases of lung cancer worldwide every year and about 75-85% of these are NSCLC. 10% of cases with NSCLC have a mutation in the gene responsible for making EGFR, and three quarters of these patients respond well to TKIs. However others are unresponsive, and, even for the people ...]]> http://www.medindia.net/news/rnai-could-enhance-lung-cancer-treatment-99150-1.htm http://www.medindia.net/news/climate-change-raises-incidence-of-respiratory-diseases-98890-1.htm Global climate change magnifies the effects of pollution and will worsen the incidence of asthma, allergies, infections and cardiovascular diseases worldwide, says a study. "Since my research focuses on environmental air pollution and its impact on the respiratory system, my biggest concern has been with issues of air quality," said Kent Pinkerton, professor of paediatrics at the University of California, who co-authored the study. "These include more smoke and particulate matter from more ...]]> http://www.medindia.net/news/climate-change-raises-incidence-of-respiratory-diseases-98890-1.htm http://www.medindia.net/news/diesel-exhaust-increases-lung-cancer-risk-98314-1.htm A two-decade long study conducted by National Cancer Institute in the United States has found that diesel exhaust increases the risk of lung cancer. The researchers tracked more than 12,000 miners working in mines such as potash and lime where diesel powered equipments are widely used. In the report, published in the Journal of the National Cancer Institute, the researchers wrote that those who were the most exposed to harmful fumes were three times more likely to die due to lung cancer. While ...]]> http://www.medindia.net/news/diesel-exhaust-increases-lung-cancer-risk-98314-1.htm http://www.medindia.net/news/energy-poverty-creating-a-respiratory-disease-epidemic-97733-1.htm Energy poverty leads to severe respiratory diseases killing nearly two million people worldwide each year, say researchers. "Energy poverty is one of the biggest human welfare issues of our day," says Hisham Zerriffi, an assistant professor with the Liu Institute for Global Issues at UBC who is presenting his work at the 2012 Annual Meeting of the American Association for the Advancement of Science (AAAS) in Vancouver on Feb. 17. "We're talking about more people who die each year from cooking than from malaria....]]> http://www.medindia.net/news/energy-poverty-creating-a-respiratory-disease-epidemic-97733-1.htm http://www.medindia.net/news/elderly-lung-cancer-patients-may-not-get-survival-benefit-with-common-postoperative-radiotherapy-97581-1.htm Post-operative radiation therapy (PORT) may not prolong life in older people with locally advanced disease, according to researchers from Mount Sinai School of Medicine. PORT is a controversial yet frequently administered treatment for lung cancer, The findings appear in the February 13 online edition of ICancer/I, a peer-reviewed journal of the American Cancer Society. In patients with non-small cell lung cancer (NSCLC), the standard of care is surgery to remove the tumor. However, ...]]> http://www.medindia.net/news/elderly-lung-cancer-patients-may-not-get-survival-benefit-with-common-postoperative-radiotherapy-97581-1.htm http://www.medindia.net/news/risk-factors-associated-with-bleeding-in-lung-cancer-97267-1.htm bMassive acute bleeding in the lung, called pulmonary hemorrhage (PH), is a fatal complication seen in lung cancer patients treated with chemotherapy and/or radiotherapy./b A recent study has unveiled the risk factors that predispose patients to pulmonary hemorrhage; bmajor/b blung cavities and squamous cell variant of lung cancer are independently associated with PH./b Chemoradiotherapy, a combination of chemotherapy and radiotherapy, is a widely used mode of treatment for patients with lung cancer....]]> http://www.medindia.net/news/risk-factors-associated-with-bleeding-in-lung-cancer-97267-1.htm http://www.medindia.net/news/kicking-the-butt-can-help-relieve-respiratory-symptoms-caused-by-regular-smoking-97150-1.htm Symptoms of respiratory problems caused by incessant smoking among young adults improve within weeks after they manage to drop the habit, a new study published in the journal Pediatric Allergy, Immunology and Pulmonology. The study was conducted by researchers from the University of Texas who observed two groups of college students aged between 18 to 24 years. More than half of the students had smoked at least 5 cigarettes a day and had done so for over a period of five years. While one group ...]]> http://www.medindia.net/news/kicking-the-butt-can-help-relieve-respiratory-symptoms-caused-by-regular-smoking-97150-1.htm http://www.medindia.net/news/lung-cancer-testing-is-required-confirms-new-research-97098-1.htm Diverse types of lung cancer act in different ways, signifying they are essentially different diseases. According to a University of Colorado Cancer Center study published in ICancer/I, the official journal of the American Cancer Society, different subgroups of non-small cell lung cancer (NSCLC) show distinct patterns of spread in the body. The study looked at 209 patients diagnosed with stage IV non-small cell lung cancer separated into four different molecular subgroups using testing ...]]> http://www.medindia.net/news/lung-cancer-testing-is-required-confirms-new-research-97098-1.htm http://www.medindia.net/news/kicking-the-butt-reduces-respiratory-symptoms-within-weeks-97067-1.htm A new study has found that young smokers who quit smoking for at least two weeks report fewer respiratory symptoms, especially coughing. For the finding, Karen Calabro, DrPH and Alexander Prokhorov, MD, PhD, The University of Texas MD Anderson Cancer Centre, Houston, compared self-reported respiratory symptoms among two groups of college students who participated in programs designed to motivate them to stop smoking. One group achieved smoking cessation for two weeks or longer and the other group failed to stop smoking....]]> http://www.medindia.net/news/kicking-the-butt-reduces-respiratory-symptoms-within-weeks-97067-1.htm http://www.medindia.net/news/lung-cancer-may-be-combated-in-a-better-manner-with-combination-drug-therapy-97039-1.htm A study by the Translational Genomics Research Institute (TGen) and Van Andel Research Institute (VARI) has stressed that combination drug therapy may be needed to combat non-small cell lung cancer (NSCLC). The study, "STAT3 is Activated by JAK2 Independent of Key Oncogenic Driver Mutation in Non-Small Cell Lung Carcinoma," was published online today, Feb. 2, 2012, by the IPublic Library of Science (PLoS) ONE/I. The study found that in NSCLC - the most common form of lung cancer - that ...]]> http://www.medindia.net/news/lung-cancer-may-be-combated-in-a-better-manner-with-combination-drug-therapy-97039-1.htm http://www.medindia.net/news/new-genetic-subtype-of-lung-cancer-defined-by-massachusetts-general-study-97011-1.htm The Massachusetts General Hospital (MGH) Cancer Center's investigators' report has defined the role of a recently keyed gene abnormality in a lethal form of lung cancer. Tumors driven by rearrangements in the ROS1 gene represent 1 to 2 percent of non-small-cell lung cancers (NSCLC), the leading cause of cancer death in the U.S. The researchers show that ROS1-driven tumors can be treated with crizotinib, which also inhibits the growth of tumors driven by an oncogene called ALK, and describe the ...]]> http://www.medindia.net/news/new-genetic-subtype-of-lung-cancer-defined-by-massachusetts-general-study-97011-1.htm http://www.medindia.net/news/bronchoalveolar-lavage-and-lung-clearance-index-may-help-detect-early-cystic-fibrosis-lung-disease-96736-1.htm A new study from Australian researchers has revealed that the lung clearance index (LCI) is a sensitive non-invasive marker of early lung disease in young children with cystic fibrosis (CF). "We found that LCI is elevated early in children with CF, especially in the presence of airway inflammation and Pseudomonas aeruginosa," said Yvonne Belessis, MBBS, MPH, PhD, respiratory staff specialist at the Sydney Children's Hospital. "LCI may not only be a marker of early CF lung disease, but may be ...]]> http://www.medindia.net/news/bronchoalveolar-lavage-and-lung-clearance-index-may-help-detect-early-cystic-fibrosis-lung-disease-96736-1.htm http://www.medindia.net/news/new-test-accurately-predicts-death-risk-from-lung-cancer-96661-1.htm A new gene-based test may help to predict the death risk in patients with lung cancer more accurately than the standard methods, according to researchers. The findings, from two independent clinical trials in the United States and China, published in the British medical journal The Lancet, should help doctors to make more accurate prognoses and better choices for treatment, the scientists said. Lung cancer is the most lethal type of the disease worldwide, claiming some 1.4 million lives ...]]> http://www.medindia.net/news/new-test-accurately-predicts-death-risk-from-lung-cancer-96661-1.htm http://www.medindia.net/news/Scientists-Report-Another-Advance-in-Lung-Cancer-Treatment-96426-1.htm An advance in the treatment of a specific kind of lung cancer is being reported by scientists from the University of Colorado Cancer Center. The team has documented how anaplastic lymphoma kinase (ALK) positive advanced non-small cell lung cancer (NSCLC) becomes resistant to a drug targeting the abnormal protein in the cancer. It's the first time scientists have analyzed the frequency and type of drug resistance in ALK positive patients taking crizotinib. Crizotinib, a tablet, shrinks tumors ...]]> http://www.medindia.net/news/Scientists-Report-Another-Advance-in-Lung-Cancer-Treatment-96426-1.htm http://www.medindia.net/news/Ganetespib-in-KRAS-Mutant-Non-Small-Cell-Lung-Cancer-96020-1.htm Research has revealed that the investigational drug ganetespib slowed the growth of cancer cells taken from non-small cell lung cancer tumors with a mutation in the KRAS gene. Ganetespib is a synthetic second-generation Hsp90 inhibitor. The drug was even more active when combined with traditional lung cancer treatments and other investigational targeted therapies, according to preclinical study data. David A. Proia, Ph.D., and Jaime Acquaviva, Ph.D., scientists at Synta Pharmaceuticals Corp....]]> http://www.medindia.net/news/Ganetespib-in-KRAS-Mutant-Non-Small-Cell-Lung-Cancer-96020-1.htm http://www.medindia.net/news/Tracing-Method-Studies-Circulating-Tumour-Cells-in-Lung-Cancer-Patients-95981-1.htm Technique to examine circulating tumour cells in the blood of patients with non-small cell lung cancer has been devised by researchers. This method, which can analyze a sample size as small as three cells, may allow clinicians to track cancer progress and treatments and could help them develop new therapies. "We have developed an extremely sensitive test that could be able to detect mutations present in circulating tumor cells (CTCs), and we are hoping that from their characterization, we would ...]]> http://www.medindia.net/news/Tracing-Method-Studies-Circulating-Tumour-Cells-in-Lung-Cancer-Patients-95981-1.htm http://www.medindia.net/news/Potential-Genetic-Origins-Pathways-of-Lung-Cancer-in-Never-Smokers-Mapped-95966-1.htm In never smokers, researchers have identified mutations and pathway changes that lead to lung cancer. Never-smokers (defined as an individual who smoked fewer than 100 cigarettes in his or her lifetime) are estimated to account for 10 percent of lung cancer cases. However, in the past, researchers have not examined this patient population as extensively as they have studied patients with lung cancer who smoked, according to Timothy G. Whitsett, Ph.D., senior postdoctoral fellow in the cancer ...]]> http://www.medindia.net/news/Potential-Genetic-Origins-Pathways-of-Lung-Cancer-in-Never-Smokers-Mapped-95966-1.htm http://www.medindia.net/news/Non-Small-Cell-Lung-Cancer-Patients-may-Not-Get-Survival-Benefit-With-Sorafenib-95921-1.htm Data presented at the AACR-IASLC Joint Conference on Molecular Origins of Lung Cancer: Biology, Therapy and Personalized Medicine reveals that sorafenib was effective in patients with non-small cell lung cancer and a KRAS mutation, but survival rates were reportedly "unsatisfactory". Patients with lung cancer and a KRAS mutation are believed to have a poor prognosis and may not benefit from treatment with epidermal growth factor receptor tyrosine kinase inhibitors, according to study author Wouter W....]]> http://www.medindia.net/news/Non-Small-Cell-Lung-Cancer-Patients-may-Not-Get-Survival-Benefit-With-Sorafenib-95921-1.htm http://www.medindia.net/news/Lung-Cancer-may-be-Prevented-by-Estrogen-Targeting-Drug-Combo-95911-1.htm In mice, a combination of estrogen-targeting drugs significantly reduces tobacco carcinogen-induced lung tumors, reveals clinical study. "Antiestrogens have been shown to prevent breast cancer in some women," said Jill M. Siegfried, Ph.D., professor in the department of pharmacology and chemical biology at University of Pittsburgh Cancer Institute. "If antiestrogens can prevent lung cancer as well, this would be a major advance, because these drugs are safe to give for long periods and there are no approved ways to prevent lung cancer....]]> http://www.medindia.net/news/Lung-Cancer-may-be-Prevented-by-Estrogen-Targeting-Drug-Combo-95911-1.htm http://www.medindia.net/news/Researcher-Hopes-To-Develop-a-Test-to-Detect-Lung-Cancer-Early-95507-1.htm Sai Yendamuri, MD, FCCP, a researcher from Roswell Park Cancer Institute (RPCI) hopes to develop a screening test that may help to diagnose lung cancer in patient. Lung cancer claims more lives in the United States each year than breast, prostate and colon cancers combined due to the fact that it often goes undetected until the disease has reached an advanced and more difficult-to-treat stage. Currently, biopsies are the only sure way to detect lung cancer, and they are highly involved and invasive for patients....]]> http://www.medindia.net/news/Researcher-Hopes-To-Develop-a-Test-to-Detect-Lung-Cancer-Early-95507-1.htm http://www.medindia.net/news/Coming-Soon-Biosensors-to-Detect-Lung-Cancer-95288-1.htm Researchers are in the process of developing biosensors to detect tumor markers of lung cancer in exhaled breath. This will be possible because of the changes produced within the organism of an ill person, changes reflected in the exhaled breath of the patient and which enable determining the presence of this type of marker during the initial stages of the disease. Tecnalis, through the Interreg project Medisen, is contributing to develop biosensors with lung cancer patients, treated ...]]> http://www.medindia.net/news/Coming-Soon-Biosensors-to-Detect-Lung-Cancer-95288-1.htm http://www.medindia.net/news/Gene-Fusion-Linked-to-Lung-Cancer-Identified-95283-1.htm Gene fusion that could explain a significant proportion of lung cancer cases in never-smokers has been identified by researchers. Recent strides have been made to identify gene mutation events driving cases of lung adenocarcinoma in never-smokers, but the underlying genetic events leading to these lung cancers still remain unknown in a large number of cases. In this report, using a combination of genome sequencing and RNA sequencing, a team of researchers in South Korea has characterized ...]]> http://www.medindia.net/news/Gene-Fusion-Linked-to-Lung-Cancer-Identified-95283-1.htm http://www.medindia.net/news/BP-Drug-Limits-Lung-Disease-95030-1.htm Lostartan - a drug widely used to treat high blood pressure reduces cigarette smoke-induced lung disease in mice, shows study. The discovery by Enid Neptune and colleagues, at Johns Hopkins University, Baltimore, provides hope for the development of therapies for chronic obstructive pulmonary disease (COPD). COPD is among the most common causes of death in the US. It is a smoking-related disease for which there are currently no disease-altering therapies. Losartan blocks the protein ...]]> http://www.medindia.net/news/BP-Drug-Limits-Lung-Disease-95030-1.htm http://www.medindia.net/news/Breath-Test-Can-Detect-Lung-Cancer-94935-1.htm A new study by Metabolomx, a diagnostic company, have found that breath test can help in identifying and differentiating between the types of lung cancer in humans. The seminal study, conducted at the Cleveland Clinic and led by Dr. Peter Mazzone, used Metabolomx' first-generation colorimetric sensor array, and reported accuracy exceeding 80% in lung cancer detection, comparable to computerized tomography (CT) scan. Further, the study found that Metabolomx' first-generation colorimetric sensor ...]]> http://www.medindia.net/news/Breath-Test-Can-Detect-Lung-Cancer-94935-1.htm http://www.medindia.net/news/Australian-Actor-Harold-Hopkins-Dies-from-Mesothelioma-94642-1.htm ...]]> http://www.medindia.net/news/Australian-Actor-Harold-Hopkins-Dies-from-Mesothelioma-94642-1.htm