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 Medindia » Blood test »  Molecular Test »  Breakpoint cluster region rearrangement in CML
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Breakpoint cluster region rearrangement in CML
Lab Test
Test Breakpoint cluster region rearrangement in CML
Indication This test characterize and monitor chronic myelogenous leukemia (CML)
Physiology CML is characterised by reciprocal translocation between chromosomes 9 and 22 producing the philadelphia chromosome. The translocation involves a gene rearrangement of the breakpoint cluster region gene located on chromosome 22 with c-abl oncogene on chromosome 9.
Normal Range Philadelphia chromosome has been found in 20% to 25% of patients with acute lymphoblastic leukemia and 2% of patients with acute myelogenous leukemia (AML)
Interpretation Chromosome analysis, Polymerase chain reaction
Sample No rearrangement observed
Test Method Nucleic acid technology
Related Tests Blood, bone marrow
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Member Comments ( 2 )
i have thyroid problem because of which i have gained weight i.e. obese, i am taking thyronorm 150 mcg...I have many problems as i said earlier i am obese, i am not having my menstruation properly...how to decrease weight and get back my periods...i have shown atleast to four to five doctors (gynecologist as well as endocrinologist) but all of them think me an experiment material and just give medicines and tell all will be normal....no one has cured my problems....only mint money and test on me...please help
(Posted by Suj113, India Date : 2/25/2011 )
If a patient of Bronchietasis comes with foul smelling breath then you must think and treat anaerobic infection. Patient becomes free of smell within 3 days of anti anaerobic therapy.
(Posted by ANWAR, Pakistan Date : 2/10/2010 )


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